I thought I would be a fast responder – but I am not!

[PinkPin]

I assumed this because I am unusually sensitive to any medication and have to start really at a very low dose.

I have been on Mourjana for two months now, currently at 5 mg, and my average weight loss is less than a pound a week. For a few weeks, I lost nothing at all.

So, it turns out I may be in fact a slow responder, or just an average responder! Can anyone relate?

PS. I didn’t get much in the way of side-effects either, which was a surprise, although I have been very conservative in terms of micro-dosing.

Are you taking 2 x 2.5mg on the same day to use up a pen, or 2.5mg twice a week?

If taking twice a week it is not the same effect as taking 5mg and taking an odd dosing schedule makes it difficult for others to relate to or comment on.

What do you mean you are sensitive to other medications - do you mean they work well for you in a positive way in low doses, or you get negative side effects. Are they similar medications to Mounjaro that makes you think you would have a similar reaction?

Did you attempt to take Mounjaro as prescribed first to see how you reacted or go straight to odd doses and schedules?

I don't really get this people 'thinking they would be a quick responder' based on what? and then sort of being disappointed they aren't losing much on a really low dose?

Take it as prescribed for a start. You also don't have that much to lose so sounds like a reasonable, steady weight loss. How much were you able to lose in a week before starting on it?

What a pointless waste of money though.

She’s less than a pound a week and nothing for the last few. That’s not steady and reasonable, she’s not even hitting a pound average.

OP what is the reason for you taking lower doses instead of titrating? Are you struggling with side effects?

It makes sense to titrate up more slowly if you are experiencing severe side effects, but if I have understood correctly that you are taking 2 half doses each week, then you are unlikely to benefit from the action of the drug as it is intended. Your practitioner will be able to explain this to you unless they are an online muppet or hairdresser buying on the grey market.

People who have had big reactions to medicines in the past tend to be conservative and err on the side of safety. I’m very cautious with antidepressants, but ask for extra anaesthetic at the dentist as I don’t seem to respond to that at all!

OP says she thought she would be a fast responder because of her previous experiences. That’s fair enough. A few weeks in she feels she isn’t going to be a fast responder after all.

OK she isn’t taking it weekly but spreading the dose so that could be affecting how it works- and asking here is a good way to find out.

Pouring scorn on someone is unreasonable.

I’m the same so I feel your pain. Some months I haven’t even lost a pound a week. If it’s any consolation it adds up over time. Think it was about April I started and I have lost just 2stone and 5lbs and dropped 2 dress sizes. I got up to 15mg as quick as I could hoping for faster loss and never saw an improvement at a higher dose sadly.

You’ve only got a couple of stone to lose? It’s not really designed for you and you are not using it as intended so it’s not remotely surprising that you’re losing at a slower rate than someone who is starting from a very obese position and taking it properly.

I am also on MJ and find it very effective, but you can't expect to take it and have it fix your weight issues on it's own.

Are you tracking calories?
Have you upped your water intake?
Do you walk or take gentle exercise each day?

You need to use it to change habits and it will support with that in my experience, but on it's own you can still decrease what you eat but not lose weight as you are consuming excess calories.

what was your bmi to start off and height /weight

you say you want to lose 2/3 stone. Which is it

take mj as you are meant to. One dose a week not 2 small doses

if on 5 now and been 2mths time to go to 7.5

it can take a few doses to find the right one

not a lot happened to me till 10 then was good for a few weeks then needed to go up again as hungry /snacking etx

now on 15

I don’t get suppression the way some do on here but I have lost weight - 4st since April - not all of it on mj

you also need to make sure eat the right foods and have a calorie loss to lose weight

it’s not a magic cure in the fact you do jab and nothing and loss

you need to overhaul your life as well

The only reason I lost over 3 stone was because I worked out my tdee and stuck most of the time to 1200 calories a day. If you aren't eating in a calorie deficit you won't lose weight no matter what dosage you're on. If you aren't taking it correctly, you're wasting your money.

You might be better looking a thread for your month of starting MJ. They are generally very supportive and open to discussion about how your journey is going.

I thought I'd be a super responder with no real evidence and that I'd stay on very low doses. But I'm a slow loser but that's ok. It takes how long it takes but I do feel I will get to where I want to be.

Micro-dosing is still very new and not recognised by the main private pharmacies. But it's clear from articles I've read that private clinics are moving forward with this. And there's lots of evidence in this board that people are altering dosages to work out what suits them. I think it's a very interesting space and imagine weight loss treatments will become much more flexible and bespoke. Probably at a cost!

She said 2 to 3 stone and depending on her height she could be obese. So why make a judgement like that??

You have to be really short or have a high goal weight for you to be obese with only 2 stone to lose. I can make whatever judgements I like, she’s already said she’s not following usage guidelines.

Yes that’s true she is wasting her money, tik tok has a lot to answer for.

but she said 2 to 3 and she didn’t say what bmi she wished to get to or what her height was, so sure be judgey but it’s highly feasible you’re wrong.

Well said..!

My starting weight of 13s 10 puts me in the obese category (just - admittedly). 2.5 loss takes me into the healthy range. I’m 5’7” so hardly short.

You can’t make a claim of being a slow responder when you arnt using the medication as prescribed. At no point has your body received a full 5mg dose.

MJ has a half life, therefore each day the amount you have in your system decreases.. at best at any given time you’ve probably only had may 3-3.5 in your system.

what you are doing falls outside of the highly strict trials of MJ where such statements are made, if you’re not taking it as prescribed ( which you should and unless your qualified provider told you to do so, is questionable) you can’t make any such statement.

if you are taking it twice a week because of intense symptoms or some other health related issues, you should seek the advice and counsel from the qualified provider.

as for your weigh loss, or lack of. Who could say.. you’re not using the meds as prescribed and we don’t have a daily food diary or your water intake , so any input from this boards members is based on incomplete information and pointless.

speak to a qualified prescriber and let them tell you what’s wrong - I suspect the first thing they will suggest is : TAKE AS PRESCRIBED!

I lost 4lb in a month on 2.5mg. I was disheartened. Tbh because of all the success stories I read on SM. Then I got real with myself and carried on. No micro dosing. On 5mg I lost 7lb in 2 months. Ive followed cal def, high protein, high water consumption etc etc. Then I went on 7.5mg for month 4 for 2 months then now on wk2 of 1st 10mg, ive consistently lost approx 2lb a week on 7.5 and 10. Im very happy, id rather be slow and steady. You're body needs a chance to get used to the drug. 2.5mg and some say 5mg too, are starting doses. It's a marathon not a sprint

It sound like you will need to keep increasing the dose. No need to split if you haven’t had side effects. Come and join us in the slow losers club. There a a few of us losing 1-2 lb per week (when we are not plateauing). It works differently for everyone.