Mounjaro triggered anxiety? To stay or to go

[ForOchreCrab]

Hey all,

I'm looking for some non-judgmental advice please.
I'm on week 5 of the injection and suppose to take the next dose today but I've had incredible anxiety. Now this is not like me at all! I've stopped going out, seeing people, all the things I use to enjoy now fill me with dread and if I can, I will get out of them.

I know this isn't me so I've already gone to my GP to see if there is something else going on and a bunch of bloods have been taken.

But I'm wondering if it is the injection, its the only thing thats changed.
I did try to post in a facebook group I'm part of for advice but both posts got rejected by admin. I don't doubt this injection is doing wonders for weight loss but I'm weighing up whether it comes at a cost of mental health. Appreciate this doesn't effect everyone the same.

It might also sound ridiculous but these pens are expensive, I've got three doses left in mine and I'm not sure I can comfortably put it in the bin.

Advice: ride it out and take the next injection or pause/stop and bin the pen?

I think in my heart I know what to do, I think "what would I tell a friend" but I kinda need to know others thoughts who are going on the same journey.

I've just completed my first month of sertraline as I tried herbal meds, meditation, breathing techniques and CBT but I just couldn't overcome the panic attacks or severe anxiety. It really was affecting every part of my life, it's an awful awful feeling. I've never suffered from mental health like this before. I do thankfully finally feel like I'm slowly getting back to me, I'm on CBT stage 2 and as said, sertraline.

That was me as well. I’m entering 5th week of sertraline now and feel so much better, anxiety is still lingering though so am seeing my GP today but it is nowhere near as crippling as it was before.

The poster who stopped sertraline it does have awful side effects when you go on it and I was starting and stopping until I just said to myself I had to stick with it. It was terrible but the side effects subsided three weeks in. I also think that mounjaro interferes with the sertraline somewhat until it leaves our bodies.

wishing everyone a speedy recovery.

I felt the same way but stick it through. I was also panicking about taking the sertraline and the side effects were terrible but stick with it. Mine settled about three weeks in but not every day was bad with regards to the side effects. Sertraline really works. My GP advised taking it in the morning to get the full effects of it. I truly understand how you are feeling, it’s awful. I’m supposed to be upping my dose to 100mg from next week and my GP advised staying on that dose for a year to get the full therapeutic effect.

What side effects did you notice with sertraline? I noticed the first couple of weeks anxiety was actually worse and very shaky hands

Have been off Mumsnet a while, so just saw this thread again. Hope you lovely ladies are doing ok, and starting to feel better. I just wanted to give a little update - I was someone that had really really bad anxiety, panic attacks and palpitations caused by mounjaro from the very first dose. I’ve now been on mj since October (9 months), and have found that as long as I keep my dose low, the anxiety symptoms have gone and my body got used to it. I know that isn’t the case for everyone, but this is my experience. I’ve now been on the same dose for months, and whilst I’m sure I could lose more going up, just cannot face all those symptoms returning!! X

my anxiety also worsened for a while but I kept reassuring myself to stick with it and that this would evenirslky subside. I also had headaches which were a weird sensation / migraine-ish and sometimes like a pressure feeling. This was not everyday - I had good days as well amongst all the side effects. When I started I was taking them at night which made me feel anxious to sleep so the GP suggested I take them in the morning which has helped. Stick with it and it’s normal to be fearful and panic about the actual taking of the sertraline. I am now starting to feel like myself again.

Mounjaro caused my antidepressant to stop working last October. I’m still very ill now and trying my second antidepressant this year.

I’m so sorry you experienced and I really hope the second antidepressant works.

I have pre-existing occasional anxiety which is managed very well through medication and therapy. I decided to start taking Mounjaro and was fine for the first week. Then second week bam! Horrific panic attacks, extreme anxiety and suicidal thoughts that scared the shite out of me. I knew it was from Mounjaro. I decided to throw the rest of the pen in the bin as I really could not continue mentally. Shame as it really helps with weight loss but at what cost???? It does not really seem to be documented too much with is really scary for people like me that want to start on the journey. Honestly I have never felt so mentally unwell in my life it was very very scary.

I help your feeling better soon. It took me 5 months to realise its was the Mounjaro triggering panic attacks and crippling anxiety, stopped taking it in jun/July last year and still struggling now.
I have gone back on Ozempic and recently been changed to wygovy - same drug as Ozempic however wygovy is licensed for higher doses. So far so good! Though from a weight loss point of view not as good as Mounjaro.
However my Mental health had to come first.
You can report your side effects to the BNF - if your UK. Not sure who it is in other countries?!

Saxender gave me terrible anxiety. Just horrific. Fortunately it was a daily jab.

Wegovy made me calmer.

Havent tried MJ.

as this is not on a list of common side effects i would encourage you all to report this under the yellow card reporting system . this is a new drug and new SE this needs to be logged.I am a diabetes nurse and prescribe for pts and only a very few have reported anxiety /palpitations as a side effect. it does seem to pass as the body gets used to the drug so please bear with it.

Sertraline almost always works within about 10-14 days. It’s like a switch flips and all your anxiety is gone. Well it was for me!

You can ask your GP for Propranolol in the meantime to stop the physical panic side effects.