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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Scared about weight loss drugs

98 replies

Nicecuppatea2025 · 12/01/2025 00:14

I need to lose weight. 5 stone. I’m very fat. Would love to be able to tie my shoe laces without puffing.

I’ve read in the news about people dying from weight loss drugs. I’d love to give it a try but I’m shit scared very nervous about it.

Any thoughts? (Apologies for yet another weight loss jabs thread). And do I have to be referred by a doctor (I’m in the uk).

OP posts:
Snozzlemaid · 12/01/2025 18:11

MrTiddlesTheCat · 12/01/2025 17:32

I had gallstones and my gallbladder removed in 2016 with just an ultrasound for diagnosis.
And my dd had her gallbladder removed a few weeks ago again following an ultrasound.

Snozzlemaid · 12/01/2025 18:13

Whilst there may be other ways to diagnose, the usual way is just a quick ultrasound.

marshmallowfinder · 12/01/2025 18:30

Haven't rtft, but I went with Wegovy as looked safer, been out longer and BHF approve, which was reassuring.

IsItSnowing · 12/01/2025 22:12

I had a CT with dye injected done in A&E when I was admitted for infected gallbladder. Didn't know I had gallstones until then.
They did an MRI a few weeks after my surgery to make sure there were no stones in the bile duct.

Jabtastic · 12/01/2025 22:14

marshmallowfinder · 12/01/2025 18:30

Haven't rtft, but I went with Wegovy as looked safer, been out longer and BHF approve, which was reassuring.

Did you have any side effects?

I'm going to get my gall bladder checked and then I may try Wegovy instead of Mountjaro it was too strong for me.

BookishType · 12/01/2025 22:20

I think you’re risking your health more by being morbidly obese. Mounjaro is a miracle drug and you should try it, if you’re suitable.

MissyPants · 12/01/2025 22:36

@lovealongbath weight loss is different. You can control it by what you put in your mouth and through exercise.

lovealongbath · 12/01/2025 22:39

MissyPants · 12/01/2025 22:36

@lovealongbath weight loss is different. You can control it by what you put in your mouth and through exercise.

aye right!

MissyPants · 12/01/2025 22:43

? @lovealongbath
So weight loss is not associated with diet and exercise? What are you going on about?

jellybeanlover2 · 12/01/2025 22:55

Retiredearly61 · 12/01/2025 00:48

Same here,exactly the same people joining year after year. And all the discussion amongst members about saving up sins for weekend blow outs and alcohol. It was dysfunctional

It’s a successful business model isn’t it? People just join/fail to lose weight/leave/rejoin, and a small number actually lose weight and keep it off

Undrugged · 12/01/2025 23:16

Nicecuppatea2025 · 12/01/2025 00:14

I need to lose weight. 5 stone. I’m very fat. Would love to be able to tie my shoe laces without puffing.

I’ve read in the news about people dying from weight loss drugs. I’d love to give it a try but I’m shit scared very nervous about it.

Any thoughts? (Apologies for yet another weight loss jabs thread). And do I have to be referred by a doctor (I’m in the uk).

You’re probably much more at risk of very serious and catastrophic health conditions being obese, in the longer run, than from Mounjaro/Ozempic. At least if you’re in mid life: if you’re 21 it might be different!

Undrugged · 12/01/2025 23:32

From personal experience however, I will say that the jabs are not the answer to all our prayers unless we either stay on them for life, or completely remodel our diet and excercise while one them and stick to it.

if you remove the appetite suppressant effect and eat to appetite in future, that’s alright as long as you have a calorie in/out balance. If you’re predisposed to really, really loving unhealthy food (me, and about 80% of the population) then watch out when the jabs stop. They give you a huge security blanket because they make the good/bad stuff much less desirable and pleasurable. When the chemical cosh comes off, it’s harder.

Im a super responder to this class of drugs, for what it’s worth -to the point I have to take multivitamins and lift weights otherwise I’d probably be deficient in many things and lose muscle mass.

I think this class of drug is really transformational but there is the thorny issue of what happens after. It reminds me a bit of the SSRI revolution, which changed many peoples’ lives. Getting off them after long term treatment is challenging. At least with MJ/Oz there is no psychological withdrawal when you stop - just a resurgence in desire for cheese/crisps/cream cakes 🍰

marshmallowfinder · 13/01/2025 03:31

Jabtastic · 12/01/2025 22:14

Did you have any side effects?

I'm going to get my gall bladder checked and then I may try Wegovy instead of Mountjaro it was too strong for me.

A little bit of gassy burping and occasional slight constipation but fine otherwise.

Gettingslimmer · 13/01/2025 07:42

Undrugged · 12/01/2025 23:32

From personal experience however, I will say that the jabs are not the answer to all our prayers unless we either stay on them for life, or completely remodel our diet and excercise while one them and stick to it.

if you remove the appetite suppressant effect and eat to appetite in future, that’s alright as long as you have a calorie in/out balance. If you’re predisposed to really, really loving unhealthy food (me, and about 80% of the population) then watch out when the jabs stop. They give you a huge security blanket because they make the good/bad stuff much less desirable and pleasurable. When the chemical cosh comes off, it’s harder.

Im a super responder to this class of drugs, for what it’s worth -to the point I have to take multivitamins and lift weights otherwise I’d probably be deficient in many things and lose muscle mass.

I think this class of drug is really transformational but there is the thorny issue of what happens after. It reminds me a bit of the SSRI revolution, which changed many peoples’ lives. Getting off them after long term treatment is challenging. At least with MJ/Oz there is no psychological withdrawal when you stop - just a resurgence in desire for cheese/crisps/cream cakes 🍰

I agree with you you need to transform your eating habits or stay on. But I don’t agree that doesn’t mean they are the answer to our prayers.

firstly, of course you need to transform how you eat and exercise, it is the same for maintenance after any diet. If you go back to what you did before, it will have the same result, getting fat. Madness, as they say, is doing the same thing over and over and expecting a different result.

but if you can’t do that, stick to the changes, then yes you need to stay on them. And we can. I will. I accept that it is very likely I will maintain for a period, a year, maybe five, and then it will pile back on. I’m in this for the long haul. So will stay on a maintenance dose. The drugs have multiple benefits for our health, past weight loss, so for me, that’s the route I will take.

im also aware over the next couple of years, the price will drop, as 8 more drugs hit the market, and a pill becomes available .

doisnore · 13/01/2025 13:35

Undrugged · 12/01/2025 23:32

From personal experience however, I will say that the jabs are not the answer to all our prayers unless we either stay on them for life, or completely remodel our diet and excercise while one them and stick to it.

if you remove the appetite suppressant effect and eat to appetite in future, that’s alright as long as you have a calorie in/out balance. If you’re predisposed to really, really loving unhealthy food (me, and about 80% of the population) then watch out when the jabs stop. They give you a huge security blanket because they make the good/bad stuff much less desirable and pleasurable. When the chemical cosh comes off, it’s harder.

Im a super responder to this class of drugs, for what it’s worth -to the point I have to take multivitamins and lift weights otherwise I’d probably be deficient in many things and lose muscle mass.

I think this class of drug is really transformational but there is the thorny issue of what happens after. It reminds me a bit of the SSRI revolution, which changed many peoples’ lives. Getting off them after long term treatment is challenging. At least with MJ/Oz there is no psychological withdrawal when you stop - just a resurgence in desire for cheese/crisps/cream cakes 🍰

I wish we could see a massive revolution in the food industry.

It doesn’t seem right that modern food has got us so hooked that a large chunk of people will be on these meds for life to avoid obesity.

Luminousalumnus · 13/01/2025 13:44

snowsjoke · 12/01/2025 11:22

I'm also worried about taking this although I'd love to.. How would you know if you had gallstones or pancreatitis? I've had random stomach upsets and have diverticuloses too. I'd love to try Mounjaro but am too scared yet the obesity leads to a high risk of other conditions.

I wish they would roll this out on the NHS for anyone with a BMI over 33 so we could be properly supervised and have pre-tests to rule out gallstones/pancreatic issues.

Hahaha as if the NHS pretest you for gallstones and pancreatitis!

Geranyums · 13/01/2025 13:49

People who have lost with weight loss injections are less likely than others to put it back on tho

Really? Do you have any evidence for that?

I had thought that most people unfortunately do put that weight back on after stopping the injections

Gettingslimmer · 13/01/2025 13:55

Geranyums · 13/01/2025 13:49

People who have lost with weight loss injections are less likely than others to put it back on tho

Really? Do you have any evidence for that?

I had thought that most people unfortunately do put that weight back on after stopping the injections

You can google surely. As it’s all out there?

lovealongbath · 13/01/2025 14:13

Geranyums · 13/01/2025 13:49

People who have lost with weight loss injections are less likely than others to put it back on tho

Really? Do you have any evidence for that?

I had thought that most people unfortunately do put that weight back on after stopping the injections

Evidence suggests people who diet and regain weight can regain 100% and more of the weight lost. I have been in this category many times.
Evidence suggests that losing weight on WLI you will regain 10% of what you have lost. It’s a no brainer for me 🤩

Geranyums · 13/01/2025 14:15

That sounds hopeful - thanks!

lovealongbath · 13/01/2025 14:20

Geranyums · 13/01/2025 14:15

That sounds hopeful - thanks!

have you watched the YouTube video I posted on page 2 of this thread? It’s very informative and everyone thinking about taking WLI should watch it.
All based on research.

DecayingRelic · 13/01/2025 14:20

I have read about the irreversible blindness risk of these injections and no I would not take them under any circumstances

I need to lose about one and half stone I think, I am going to just try and get more exercise and cut out the chocolate

SilenceInside · 13/01/2025 14:26

DecayingRelic · 13/01/2025 14:20

I have read about the irreversible blindness risk of these injections and no I would not take them under any circumstances

I need to lose about one and half stone I think, I am going to just try and get more exercise and cut out the chocolate

There is no general risk of irreversible blindness. That is a specific risk for people who are already diabetic and taking insulin who already have diabetic retinopathy or macular oedema, who should speak to their doctor before taking Mounjaro. Even then, the benefits for those patients in controlling their diabetes and weight may outweigh the risks, depending on their specific circumstances.

If you are not diabetic and taking it for weight loss only, there is no risk of this happening.

SilenceInside · 13/01/2025 14:38

So, that's about semaglutide which is Wegovy/Ozempic and it is a tentative link to the NAION condition that has not yet been fully studied or confirmed. The patient information for Wegovy/Ozempic has not yet listed this as a known rare side effect.

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