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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Original poster

Sobering (depressing?!) studies on life after MJ and worth consideration?

257 replies

RoastedPickleAndChips · 20/12/2024 14:31

I'm at my target weight more or less after 8 months on MJ. Lost 5 stone and am now 9 stone 12 so quite happy with all that

As most of us are aware, there's not huge amounts of information surrounding maintenance, mainly because people are only just getting there on the whole due to MJ being relatively new to the UK for weight loss

So I've been doing some reading and digging and it makes for pretty depressing discoveries

I always knew that I didn't need to 'educate myself about heathy eating and portion control etc etc.' I could practically qualify as a dietician tbh Grin and I always felt that the MJ does far far more than just suppress appetite

Have a look at this study .... https://jamanetwork.com/journals/jama/fullarticle/2812936 .... it shows that for a fact pretty much everyone will regain the weight they have lost once coming off MJ

I also read this comment from someone well informed ....

MJ is not for suppression. That’s not ever been a planned target effect.

It’s a physical, mechanical, method of action. What the drug DOES do is increase insulin sensitivity, suppresses glucagon secretion, and slows gastric emptying. These are known as the target effects.

Once you stop taking the drug, the body reverts back to higher insulin resistance, high glucagon secretion, and faster gastric emptying.

And the studies show this. There’s lots and lots of information if people spend half an hour reading the studies and trials.

SURMOUNT-4 proves that “changing behaviour” alone doesn’t work. And SURMOUNT-3 applied the drug AFTER people tried to change behaviour - and we see clear massive difference in subjects there too. So the clinical effect is clear. It’s not a tool to help you get over a hill or learn how to be healthy. No more than wearing body armour makes your skin thicker.

Anyway, thoughts? Of course I want to believe that I'll be the exception, that this time I'll keep the weight off, that of course just 'eating less and moving more' is the key

But it's not is it? MJ seems to be more than just a tool - it looks like the effects on the body are far more than I'd realised and understood

So is the answer a dose for life? (Currently not available to my knowledge?)

Thoughts? I'd love to be told the above is a load of shit Grin Thought it might be interesting to discuss anyway

OP posts:
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squidgymum · 29/12/2024 11:05

beckaellen · 21/12/2024 06:24

My plan for maintaining my weight loss is complete abstinence from all junk food. My diet is whole plant foods. I'm not eating any fatty food, added sugar or refined carbohydrates. I'm enjoying my healthy food but I don't get the big dopamine hit and craving and withdrawal that I get with junk/sugar. I know if I ever eat junk/processed food I will instantly crave more and the healthy foods I'm currently eating will seem rubbish in comparison.
Over several years I've gradually managed to get my weight down from 19 stones to 13, and now 10 stones with Mj. The longest I ever managed to diet was 3 months at a time and then I would fall off and return to bad eating and regain a chunk of the weight but usually not all so that very gradually my weight tracked down. I mean to continue tracking all calories daily for a good while into maintenance, good days and bad, and continue daily exercise for the much needed continuity and routine as well as health benefits, and continue daily weighing too. Basically, I mean to carry on making diet, sleep and exercise my main priority in life long term.
I have high food noise, I love junk food and I binge eat. I consider myself an addict and need complete abstinence to have hopes of keeping the weight off. Even now on Mj I have a high appetite and food noise, I binged 3 times in the last month but not on junk because I don't have any in the house. I try to eat my biggest, most satiating meal for breakfast, and eat lots of fibre and beans/ lentils, I get enough protein.
I'm reading a book called 'How not to diet' that approaches weight loss from a whole plant foods direction and plan to use the advice if my weight starts rising in maintenance.
I've read that insulin resistance is caused by fat clogging up our muscles so that they can't take up the glucose in the blood, so you feel tired and hungry all the time and your body doesn't burn fat. And that's why losing a lot of weight/ body fat and eating a healthier diet can reverse insulin resistance and put diabetes into remission (usually only if the diabetes is more recent).

Im exactly like you, have been eating a whole food plant based diet with minimal oil for over 3 years, I lost 5 stone but in the last year the weight plateaued a bit and then I found MJ, Im 3 weeks in. I find it difficult on MJ to eat wfpb because suppression is so high and my usual foods are difficult to get down but Im really hoping that I can eventually maintain weight loss eating a wfpb diet, one of the plant based doctors says if you eat this way you will never be obese again, and I hold on to that. Im in my 50s, I cant afford diet related illnesses. Another pb doctor says he wants to live long and die fast (he is now 91), that is how it is meant to be but so many people live long agonising deaths due to diet related illnesses.

MjMadness · 29/12/2024 23:13

Well I know I might put it all back on. I hope not and I'll try my damn hardest not to. But if I do, i won't have regretted this.

I'm late 40s. To have had some time, even if brief, where I don't have to constantly think about food, and to fulfil a life long dream of being able to wear a bikini!! (as ridiculous as that sounds!) and to feel like a slim person, even if only for a day. Well, it's worth it. 100% worth it.

I'll have experienced being slim. I'll have the memories of being slim. And that is something I don't think I could ever have without this. It is worth it, just for one day in a bikini or one day feeling free of battling cravings and hunger.

missfliss · 01/01/2025 07:58

KrankyKumquat · 21/12/2024 22:54

@financialcareerstuff
I think a lot of us like the idea of micro-dosing but in the UK, we hit the problem of the 30 day open pen issue. The Americans do it a lot but they have single dose pens which avoids this issue (but they are insanely expensive). I'm planning on trying one month on, one month off when I get down to 2.5 - which my prescriber supports.

Who is your prescriber please? Is it one of the main ones?

Lukedid · 01/01/2025 08:18

@missfliss Cloud Pharmacy is the provider that's known to offer one month on, one month off but maybe other providers are now doing it too.

KrankyKumquat · 01/01/2025 09:59

missfliss · 01/01/2025 07:58

Who is your prescriber please? Is it one of the main ones?

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It's Oushk.

missfliss · 01/01/2025 10:22

Thanks very much for answering both - appreciate it

Chewii · 01/01/2025 23:18

PinkArt · 20/12/2024 19:08

And cornflakes were created to prevent masturbation. Products evolve.
If you don't want to use WLI then don't you use them but there is no reason that the millions of people who are using it to reverse their obesity should stop.

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I can say from my lived experience that eating corn flakes does not prevent mastubation

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