Wegovy is changing my personality

[almondmilk123]

Wegovy is changing me. it's making me a lot less caring. it's improved my mood, made me less ADHD, but also has made me disinhibited and less sensitive. Maybe this is a good thing, the real me minus inflammation, but its unnerving. I'm blurting out stuff and find myself curiously not-giving-a-shit about serious problems that were previously eating me up.

this seems a serious side effect akin to a psychiatric medication. I've taken antidepressants, this is much subtler, but its similar.

I can think more clearly, but am I me?

Note, I'm only on 0.25 - the starter dose!

Anyone else?

I have expressed similar thoughts on Mounjaro!

I think its reduced dopamine - so food noise goes, but so does my shopping drive! Christmas? Can’t be doing with that this year! 🫣

My anxiety has reduced too. And I think this makes one less inhibited - not hand wringing over social matters etc.

I think I am still me, personally. I still don’t want to upset people, or be mean, I just care less about things that shouldn’t matter so much!

That's a very positive take on it. Maybe I'm too wedded to neurosis. But I dislike chemicals
Doing this I want it to come
From within

Also I have a friend who's on it and she was always insensitive but now she's off the scale. It's quite unbearable. But maybe not linked

I hear ya, but it is a chemical and that’s what MJ does?? It works on the brain, not the stomach? It literally tricks you into thinking your stomach is fuller than it is.

I may be projecting but you sound like you think maybe its a failing of some kind to have to take something that works on your hormones/brain? Its not. And I think the fact that you feel so different on it is testement to the fact that the reason so many of us can’t keep weight off/lose weight without it suggests its so much more than simple will power.

I was under the impression that MJ at least does slow your stomach emptying - it's not an illusion.

Ah sorry I've looked it up:
Wegovy, at least, does both: makes your brain feel like you are fuller, and makes your stomach empty more slowly.

Yes it does but it doesn’t magically shrink your stomach without working in your brain, sorry I was not fully clear - that’s what I was referring to. Loads of us eat without being hungry and thats why we are overweight - and what i’m responding to when OP says ‘wanting it to come from within’.

I don't mind about the losing weight coming from a drug. I'm cool with that. I just don't want it changing my personality too. Even if some of its positive.

I totally agree that weight gain is not a failure of willpower, it's a sympton of a toxic food environment.

I kind of see what you mean but I see it more as I'm not stressing over the small things.

Also in terms of not liking chemicals well the majority of behaviour from cognitive function to thirst to sex to love/ affection is driven by hormones. Hormones are chemicals. Now we make them in our body but they drive almost every aspect of mammlian behaviour. So if you had thyroid disease and needed therapy would you consider it a failing. In terms of the one targeted here, GLP-1 expression is dimished in obesity ( ref bellow) so my view is previous to taking the drug you are suffering from a deficit which among other things affects eating behaviour but also mood. So by fixing this imbalance you are not pumping your body with a chemical but rather giving it something it is missing, like taking iron for anemia.

"Both fasting and post-prandial GLP-1 levels are lower in people with obesity as compared with those in normal-weight subjects, as obesity is characterized by a blunted post-prandial GLP-1 increase 11]"
https://www.nature.com/articles/s41366-024-01461-2#:~:text=Both%20fasting%20and%20post%2Dprandial,%2D1%20increase%20%5B11%5D.

If you remove the concept of beating yourself up do you think the changes in your mood may also be a good thing. Stressing about something isn't actually productive. Clarity from a lack of anxiety is actually better for solving problems.

Well I have an update. On pen 2 the psychological effects seemed to dissipate and I had a massive depressive crash - crying all the time. Also didn't lose weight so maybe a duff pen.

Can I just stress I'm not interested in any kind of moral judgement - I agree this is a medicine like any other. Would we refuse penecillin? And obesity is deadly. Etc.

I'm just frustrated that there's this whole other side of mood and personality changes

I just want the weight loss

Historically I'm a bit of a super-responder to anything psycho active aka a lightweight and I'm used to finding nobody shares my sensitivity, not one. It could be all in my head, it could be real, nobody will ever know, not me but not anyone else either