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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Weight gain after Mounjaro

18 replies

peebles32 · 13/06/2024 15:49

Well I have lost 12lb after using one pen and about to go up to 5mg.
However, after this one I really can't afford it and this next pen will be the last one.
Once stopped, I am hoping my sugar craving has gone. However, how likely is it to put the weight back on. My friend used Ozempic and started putting the weight back on. Is it a case of back to square one again or does your brain adapt and the cravings go?

OP posts:
lizzardos · 13/06/2024 16:30

My friend lost lots of weight after gastric band operation. Because she couldn't eat lot in one go she started to have small snacks often and piled some weight. She is now in the middle of the staring weight and goal weight. She looks good now. Her face looked awful when she was in her thinnest.

AhBiscuits · 13/06/2024 21:24

It is very likely that your cravings will return. Use this time to start planning strategies to deal with them. A couple of months is not much time to bed in new habits, I think you need to be on them at least 6 really.

Cerialkiller · 13/06/2024 21:31

The studies on mounjaro were relatively promising on this with only about 20% regaining all the weight within 18months. Many regain some but not all but It's certainly seems to be no worse then any other weight loss method. As with other strategies it's the maintenance that is the difficult part.

justasmalltownmum · 13/06/2024 21:37

The cravings come back. The food noise/ chatter whatever you want to call it, comes back.

If you want it to stay off, you have to actively keep it off by exercising etc

unsync · 13/06/2024 21:53

What else have you done? Overhauled your eating? Exercise regime? It's not a magic solution and you do still need to work at food and exercise. Hopefully these should be starting to bed in now if you are on your 2nd pen, so loss may be slower, but still achievable.

CoastalCalm · 07/07/2024 04:09

I expect it will depend on whether or not you have changed habits , I see so many on Mounjaro who are living on snacks , protein bars etc and having very few actual meals - it’s not designed to be like a slim fast or meal replacement plan

3wDavid · 07/07/2024 05:45

Once you stop, the sugar cravings will most certainly come back. It doesn’t alter your habits or brain chemistry (at least in such a short term usage). As with any other diet, if you go back to your old ways the moment you stop, the weight will come back on. The way MJ helps you really, is while on it, it makes it easier to learn new dietary habits because it takes away the cravings/food noise. So you’re more successful sticking to a healthy diet. Use this time to do just that. And be realistic - it’s not realistic to expect to never have cravings or sweet tooth but figure out healthier/lower calorie options for when those times come.

DailyCake · 07/07/2024 06:02

To manage sugar cravings:

Take chromium picolinate
Try sucking one sugar-free hard sweet
Slowly sip a cup of Options chocolate (approx 40 cal)
For a cold drink - lemon juice, fresh mint leaves and xylitol in a blender with ice cubes to make a frappe which takes longer to drink

chaosmaker · 06/04/2025 10:55

Did you manage to keep the weight off @peebles32 ?

user1471503652 · 06/04/2025 12:25

I took my last dose in August after losing 2.5 stone taking me from a size 14 to a 10 and I have only gained 2 pounds. A month or so before my last dose I started thinking about dealing with cravings. So, I'd encourage soon to be stoppers to develop a plan.

I have no scientific evidence to say this but I honestly think my stomach has shrunk and I don't need as much food now.

It also did something to my brain in terms of the constant snacking and shovelling everything into my mouth, I'm much more conscious of calories.

However, you have to have the will power to keep it off. The financial investment was also a big driver, 6 months at 170 quid a pop was not something I'd want to see go to waste.

Weighing daily is also a great tip, remove the fear of weighing yourself by doing it as part of your morning routine so you can link any gains to eating behaviour or activity.

Cafog · 07/04/2025 07:36

2.5mg obviously worked well for you. Could you consider extending your next pen by a couple of doses by sticking with 2.5 or only going up to 3.75? Just to give you a couple more weeks for the good habits to bed in. Good luck x

northerneast · 07/04/2025 07:41

It’s not the Mounjaro that causes the weight loss, it’s the food you eat so if you can keep up a healthy diet without the support of MJ you will keep the weight off.

hopeishere · 07/04/2025 07:45

This is my worry. I’ve lost three stone one more to go. I’m trying to work out why I got so fat - when and what was I eating, listening to my body and asking myself am I actually hungry or am I eating just because it’s lunchtime.

chaosmaker · 09/04/2025 09:57

It's why I won't take it in the first place. I need to go back to the blood sugar diet I think, Michael Moseley. I lost 2 stone in 2 months and kept it off for a long time. Diagnosed T2 diabetic just as I started that diet and was managing it on diet alone for years. I think a jab won't help me re-reform my eating habits.

northerneast · 09/04/2025 10:02

chaosmaker · 09/04/2025 09:57

It's why I won't take it in the first place. I need to go back to the blood sugar diet I think, Michael Moseley. I lost 2 stone in 2 months and kept it off for a long time. Diagnosed T2 diabetic just as I started that diet and was managing it on diet alone for years. I think a jab won't help me re-reform my eating habits.

It’s certainly helped me. I eat better than I ever have because it has removed any desire to snack or eat ‘bad’ foods. I only take the lowest dose and still get hungry - I’m not after full suppression as I think that does stop you from being able to reframe your habits permanently. I have lost 4 stone but by far the bigger benefit for me has been the fact that I now eat 3 very good meals a day, I’m getting everything my body needs just from.

chaosmaker · 09/04/2025 16:42

Glad it worked for you :)

stealthsquirrelnutkin · 09/04/2025 19:58

My best advice is to do everything possible to improve your gut microbiome.

Add a portion of kimchi and a glass of kombucha to your breakfast. Have nuts, fruit (fresh or dried) with dark chocolate and black coffee for lunch. Serve a dollop of sauerkraut with your evening meal and get in the habit of eating kefir yogurt with berries for dessert. Aim to eat a minimum of thirty different plants each week including beans, choose healthy fats, and eat more protein and fibre.

Read the ingredient list on every item you pick up in the supermarket, and don't buy things that contain methyl cellulose, mono and diglycerides of fatty acids, artificial sweeteners or other crap you wouldn't find in your cupboards at home.

Try to leave at least 14 hours between your last meal and breakfast the next day (important for gut microbes who proliferate when the gut is empty and feed off the gut lining, making it stronger and less leaky, and producing short chain fatty acids as a bi product which improve your mood, sleep quality, mental equilibrium and cardio vascular health, and mop up particles that cause chronic inflammation (and trigger autoimmune reactions).

I wish I'd known about the importance of a healthy gut microbiome 40 years ago when I was first diagnosed with diabetes. I made the changes three years ago in an attempt to mitigate a crippling bout of rheumatoid arthritis. The effortless weight loss and ability to sleep at normal times instead of lying in bed staring at the ceiling till dawn came as a completely unexpected bonus.

It's possible to make lab rats fat by giving them gut bacteria from obese rats. It's also possible for one genetically identical twin to be obese, and the other to be slim, and the gut microbes in the obese twin will be completely different and of varieties that are associated with obesity.

Also avoid ibuprofen, I was shocked to learn that ibuprofen is a detrimental to a healthy gut microbiome as a dose of antibiotics. I think there ought to be warnings on the packet. I used to take it in rotation with paracetamol for months when my rheumatism flared up.

Avoiding UPFs means the vast majority of supermarket cakes, biscuits and breads become things to avoid. There are still some options that don't have the non-food ingredients, but you have to look carefully. A cheap bread maker might pay for itself quite quickly, and it is nice to wake to the smell of freshly baked bread, or turn your fresh pizza dough out and create your own with all your favourite toppings.

Same with most cereals and a load of breakfast bars and "healthy" drinks and yogurts that are full of artificial sweeteners. Nearly all packet and jar sauces seem to contain modified starch, but it is incredibly easy to knock together your own sauces, just like we all used to do in the olden days.

Then you pass the time thinking about what extra plants you can scoff to keep the total rising all through the week. Frozen okra? Artichoke hearts? Dragon fruit? Green nori sprinkles? Instead of feeling deprived of all your UPF laden favourites your food noise will be completely taken up with devising new ways to squeeze in yet another new plant to boost the weekly total.

JoM5958 · 08/06/2025 11:37

It’s all about the mindset. Having had gastric by pass and 10 yrs later having gained 1/3 of the lost weight back on, I’ve now been able to change the way I think about food, eating healthier and smaller portions. I’d advise seeing a CBT consultant or have some hypnotherapy. Your mind over rules your stomach

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