Going to go against the grain here. DH used to do this occassionally. Never missed a weekend away - but certainly the odd event coloured by the too much the night before.
I used to get really het up about it. Stressing before DH even went out that he'd miss the train/end up at a random station/be hungover.
We got into a viscious cycle of me nagging/expecting the worst of him...and him reacting (as he agreed afterwards) like a petulant teenager and drinking even more.
It wasn't an alcohol problem in the true sense...more a relationship problem.
We sat down when sober and I told him I felt anxious and worried and could not relax/sleep until he was home safe. Even though 80% of the time he'd have a few beers, be bit merry on arriving home but that would be it. But that in some ways the worry/nagging etc was my reaction to him going out.
He felt like he was being treated like a child and admitted that this sometimes made him think he may as well carry on drinking if he was going to get me going on at him when he got home. He also admitted that then, once he'd had 3 or 4 beers he struggled to not carry on. Maybe an alcohol problem - yes, slightly worrying - but to be honest, I could be the same.
The MN massive would have had me LTB. Instead, we agreed that
I would try and not instantly assume 1 beer = drunk
He would stick to 2 max if it was going to be "a quick drink"
He would arrange to stay in a hotel/get an Uber home if he was going to have more than 2 drinks (obviously letting me know). That was I would not worry about him ending up in the arse end of no-where/walking along a country road back from the station etc etc.
It worked.
The Uber/hotel thing meant I was relaxed. DH didn't feel the pressure from me nagging him. He realised the true expense of a night out (added £ for the hotel etc) and they became less frequent. He no longer had a few extra as a "May as well be hung for a sheep as for a lamb" mentality.
I will be honest - once the viscious cycle of drink/worry/hangover/nag went he went out and drunk a lot less.
He was being painful and childish - but my reaction was not helping.
Anyway this may all be irrelevant to you - I am just trying to say, please do not let the "This is a deal-breaker" brigade make you do something you may not need to do. If he is generally OK and this is really just a once a blue-moon then yes, have a conversation. Agree a way forward. But it doesn't have to mean the end of your marriage.