I've not lived with anyone since I leave shared housing, and I haven't had a boyfriend for years.
About a decade ago, I wrote off my car, and had to work from home for 3 weeks until I replaced it. Weekends at home were fine - I could walk in to town, to the library, to the supermarket and so on. But I struggled in the week - I had to work, not go out and see people. It wasn't good for my mental state.
It seems different this time. I think this is partly because I have been very busy with a deadline, which is a time I would have probably cut down on contact anyway. But also, I'm not missing out on my usual exercise classes, because they have been cancelled. My evening class is continuing by Skype. I've been on a couple of virtual "pub" sessions. At work, my manager is running teabreak meetings and it is increasing our sense of being a team - we're spread over different locations/countries anyway, but he's aware it could be harder for some people than others and is checking how people are doing, whereas my old manager didn't care.
But it's still not the same as seeing people face to face, whether in the office or the street. I can often go weeks or months without anyone physically touching me, so in some ways there's really no change - that must be harder for those who are only recently single. You do get inured to it over time, but I don't think it's good long-term. I still have the usual worries about what will happen if I get I'll, or fall down the stairs, will anyone notice, who could help? They're probably a bit higher up my mind than usual just now, but it's always in the background anyway.
I am very good at filling my time with things to do (and as I am still working full time, I envy all the posts about how people can learn new things and so on.) But it's still not the same as sometimes seeing people face-to-face. I am finding it easier this time, though. So far. I full understand why others might not be.