4 miscarriages, now found out why!

[Vicki469]

Hi all, I’m new to this but here goes!

I’ve had 4 miscarriages now, starting back in 2018 where I didn’t know I was pregnant till I had the miscarriage, then 1 November 2020 and 3 in 2021 already! So as you can tell, I’m more then stressed about it!
I have been back and forth to the hospital to seen the consultant, tests and scans etc…. I had a phone call from the consultant on Monday to say that I actually have a desire called FAK-TUR 5 mutation, which is a blood clotting disorder, which is cause by trauma or surgery. But can also be hereditary. I have never heard of this before. He told me that when I get a positive pregnancy test, he will start me on a few things, aspirin, 5mg folic acid, progesterone injection do the whole pregnancy and to stop 6 weeks after the birth and also cyclogest pessaries. Has anyone else been put on all of these medications to help stop a miscarriage and if so, how did it go and was the pregnancy completed? I’m really scared about trying again but now we know why I feel a little better about it, but that thought is always going to be there. Thanks

Sorry to hear about your miscarriages. Clotting disorders are the most common cause of recurrent miscarriage and normally once diagnosed and treatment is started in subsequent pregnancies there is a good result. Some good information about Factor V here

www.stoptheclot.org/wp-content/uploads/2014/02/FactorVLeiden-lw.pdf

Yes, this type of treatment is very common in recurrent miscarriage cases (I'm an RMC patient too). They often suggest it to women not only with clotting disorders but also to those whose reason for MCs cannot be found at present, as a precaution Tommy's research shows progesterone can be helpful to recurrent MC patients. In reality it all depends on the underlying cause for your MCs, sounds like yours may have been identified which is a positive sign for the future let's hope

Also do you mean Factor V Leiden OP?

Aspirin worked for me

No personal experience but my mother lost so many pregnancies I believe I was going to be her 'last try'. This was back in the 70s and I understand her obstetrician put her on low dose thyroid hormone to try to help. Current knowledge and experience has developed protocols that do make a real difference. Fingers crossed for you for next time.

I have factor V - it can cause little blood clots in the placenta which prevent the baby from getting what it needs. The meds will help, and are often prescribed even when they haven't identified the cause of recurrent miscarriages. I'm currently pregnant on my first, and my mum and nanna (who also had it) each had five kids - once it's diagnosed, it's easily managed! Just make sure after pregnancy you are not prescribed any contraception that increases the risk of blood clots.

Yes I have Factor V Leiden. Its surprisingly common but one of those conditions that unless you have a problem such a clots or miscarriages its not picked up or s
Routinely. Mine was picked up when I was 18 after I had a vein occlusion in my foot. It doesn't really affect your life day to day but basically you are at higher risk of clots and DVTS so be careful with long travel, take aspirin in advance and wear flight socks. I was warned in the future that I should start blood thinners by 12 weeks with any pregnancy, you self inject something like fragmin or clexane until 6 weeks post baby. Its not fun having to inject everyday they do sting a bit but its more than worth it to have two lovely DDs. DM if you want any more info

I’ve never been tested for anything, but have had 2 miscarriages and went on aspirin and progesterone this time in case it might help.

I’m almost 20 weeks so I would say it’s working, my other pregnancies ended before 12 weeks.

Good luck 🌈

Hi OP, I had 3 miscarriages before my first child and 2 before my second.

For the second I had progesterone from CD 21 until week 12 and then heparin injections from 5/6 week scan also until 12 weeks... She is now 6 yo...

Good luck!

When I looked it up yeah it's the V Leiden one. I've never heard of it before tho so was really confused. Just hope that all this treatment will work cause I don't think I can mentally and emotionally go through it all over again. I just couldn't get past 6 weeks so fingers crossed, I'm really nervous and a little apprehensive if I'm honest tho.

This may well be the cause OP, but please don't put more pressure on yourself. I'm speaking from experience, I'm currently 28 weeks with my little boy after 3 losses and it is hard, but you have to keep the negative thoughts away whilst staying realistic about things. Unfortunately MCs happen for different reasons - your next pregnancy could be absolutely fine with or without meds, or it can be affected by something else, for example a chromosomal issue. In my personal experience, this journey has become a lot easier once I've accepted I really do not have any control over the outcome. Remember that that your chances are still very good and especially now once you have a diagnosis, they will likely be even better. And there are other things that you could still explore, such as natural killer cells which aren't tested on the NHS. It's not an easy road by any measure but you will get there & I wish you all the luck and strenght ❤🌈

I'm currently on cyclogest pessaries. Not fun putting them in there and a bit messy but other than that had no issues with them

Willithappen- if you don't mind me asking, what's your history and why are you on them? I've just not spoken to anyone that's been on them so would just like a little bit more info. I've googled and googled but it's just getting to much and I don't know what's true and what isn't

And can anyone tell me how to work this site properly? Lol how do you DM someone? I can't do anything on here!

@Vicki469 conceived via IVF and I think it's standard protocol to go on them when doing IVF :)
I'm 'unexplained' infertility
I'm also on oestrogen tablets too. Taking both of these up until 12 completed weeks of pregnancy

@Vicki469 I used them rectally as it’s less messy, nothing leaks out of there. I put one in in the morning and one before bed, you just have to time your poos! All that matters is that the progesterone gets into the blood stream, and the rectum is very effective for that apparently!

To DM someone just copy their name and then go to your profile top right - then go to private messages and you can send from there xx

[quote Cafeaulait27]@Vicki469 I used them rectally as it’s less messy, nothing leaks out of there. I put one in in the morning and one before bed, you just have to time your poos! All that matters is that the progesterone gets into the blood stream, and the rectum is very effective for that apparently!

To DM someone just copy their name and then go to your profile top right - then go to private messages and you can send from there xx[/quote]
On the app on web browser?

@willithappen sorry to hear that. Are things going well for you k on n the IVF tho?

Definitely rectally, if you go via the front door it might irritate your cervix - I had that after several weeks and yes agreed it is more messy, you'd need to wear pads. However, rectal use wrecked havoc on my digestive system, you might have some unpleasant sude effects. But that's pregnancy and hormones for you I suppose. Cyclogest is really not an issue at all.

It's well yeah :) well hopefully. I'm 7 weeks tomorrow and have a scan so hoping everything is okay!
I do mine vaginally. Can't hold in a poo if needed haha. I don't find too much mess, just wear a panty liner

@willithappen I must admit I found the poo thing challenging! Apparently if you wait an hour it should’ve all absorbed so I just tried to hold it as long as poss when I needed to go just after putting one in hahaa. I mainly did it rectally as I was worried about some of the medicine leaking out and therefore not being absorbed by the body xx

@willithappen well good luck to you! Hope it all goes well. I don't think I could do it rectally! Even just the thought of it is making me feel wheezy! I've had to use pessaries before but never with side effects, I've ready up on them and heard there not nice.

@PurplePansy05 did you get many side effects? The main one I'm worried about is bleeding? Like should that even be happening? I have a read that about something else? 🤦🏻‍♀️

No, bleeding is very uncommon if you're on Cyclogest, although not impossible.

I have had zero side effects with the pessaries if that helps? :) think it affects women all differently.