NK cells and Recurrent Miscarriage Trial at LWH

[sue10]

Hello ladies,
i have received the Autumn 2008 newsletter from the miscarriage association and in it it talks about some trials that are going to start looking t recurrent mc's.
One of them is with Dr Siobhan Quenby whereby she is testing for uterine nkcells and usiong prednisolone as part of the treatment. The number to call if you are interested is:
01517024271. The criteria is that you are between 20 and 40 and have 3 or more consecutive mc's and have all the standard investigations without any problems being identified.

The other trial is with Dr Raj Rai at St Marys aswellas 7 other university hospitals whereby they are again looking at recurrent mc's and the use of progesterone.

Just thought i'd share this info with you all.
Takecare everyone.
sueXXX.

Hi amelied,
all the info i have is really from other peeps who are going through similar situations as ourselves. After so many mc's and little if any info from dr's etc i just thought i can't go on like this thus the research began!!! I only wish i had started researching and questionning things a few years before now but hey 'in hind sight' is a great thing!

Dr Alan Beer was (sadly passed away in 1996)is considered the main person really who spent many years looking into reasons as to why we mc and why some woman can not conceive, immune issues being his main theory. Look up the link:
repro-med.net/

You could phone the following clinic and ask for info pack, this contains up to date latest tests/theories/treatments etc,
CARE at Nottingham Dr George Ndukwe Tele:
0115 8528100

Im afraid i dont know of any clinics in Scotland but do know of some girls who travel to Nottingham to see Dr Ndukwe, some go to London the ARGC, another clinic that deals with immune issues. Also you could always phone Dr Quenby's secretary at Liverpools Womans Hospital and ask for Dr Quenby's email add to ask if she could recommend a clinic and or consultant nearer to you, Tele: 01517024271. She is at present doing trials using steroids to help lower the nk cells.

Hope this helps a little.
Takecare.
XXX.

Hi All,

This is my first post, and i am really hoping that i can get some advice from women in the same situation or have being through this traumatic experience?

For the past 5 years my husband and myself have had 4 miscarriages, i have being through the whole NHS tests at both our local hospital, we then fought to get referred to St Mary's and had another round of tests, with yet again 'nothing found'. During all this I searched on 'reasons' and did alot of research on NK Cells, so off we went to Lister as we had some cash available for testing. We had the CD69 (level 2), ana, aoa, X deletions and cystic carrier..phew! I have just being told by the nurse that i have NK cells at a high level, we await the rest of the results back.

Basically i was hoping to find out if anyone has had this testing done and your experience of it please? And your experience of Lister (Dr Thum) in particular

Thank you

Hi, I had 3 m/cs at around 8 weeks before my daughter (now 2) was born. We would like a sibling for her but I had a 'missed m/c' which I found out about at my 12 week scan in Sept 08, then just over a week ago I miscarried at 16 weeks. I haven't had the results from the post-mortum and tests yet but I'm not hopeful that they will find anything. Tests after my 3rd m/c showed a chromosomal abnormality which my consultant told me suggested it was sporoadic and mainly due to my age (I will be 40 this year).

I really don't know if I can try again without doing something different and was thinking of going for pre-implantation genetic screening (PGS) at Notthingham and tests for NK cells at Liverpool. Although I haven't had difficulty conceiving, I am starting to wonder if IVF may be the way forward? I spoke to the secretary at Liverpool and she said that although other places (like Nottingham) may offer screening for NK cells, these places only use blood tests and dont test the endometrium as they do at Liverpool.

Has anyone else been told that they are having repeated sporadic m/cs? How can they know that they are all sporadic if they only test once? Can anyone out there help me decide about PGS?

Thanks xxx

Hi Ladies, I'm taking part in the trial for uNK cells.
I have had 5 miscarriges. I am currently 6 weeks and we got a heartbeat a few days ago! We've not reached that before. Still a long way to go before we're home and dry but we've got hope and that's more than we've ever had.
Dr. Quemby and her team are fantastic, the care and advice we've received from The Womens Hospital in Liverpool has been spectacular.
There is hope, my advice is to keep on at your GP/ hospital until they refer you. Baby dust to all xxx

Hi Ladies, I'm taking part in the trial for uNK cells.
I have had 5 miscarriges. I am currently 6 weeks and we got a heartbeat a few days ago! We've not reached that before. Still a long way to go before we're home and dry but we've got hope and that's more than we've ever had.
Dr. Quemby and her team are fantastic, the care and advice we've received from The Womens Hospital in Liverpool has been spectacular.
There is hope, my advice is to keep on at your GP/ hospital until they refer you. Baby dust to all xxx

I realise this is a very old thread but it came up through some googling and I was wondering how everyone got on? Might not have a chance to find some of you now...

I am being treated for very high NK cells and doing a lot of my own research on it. Would love to know how some of you got on!