Just for the record, although it is not in direct response to this thread, but I cannot seem to find the original one I was on, I have had extensive NK cell tests and treatment as I have EXTREMELY high NK levels. I have had 9 miscarriages. The point is, if you want to get this fully tested in London the only place offering the full tests is the ARGC who get the tests done at the late Dr Beers clinic in Chicago. Although Shehata will offer you the full steroid treatment, he only does a couple of elements of the tests and my results were borderline with him. Lister also does not do the full testing.
Once you know what you have, Dr Shehata is the only Dr I know of in London who can be relied upon to give you the treatment. Raj Rai etc at St Mary's won't give you a commitment beforehand to offer the treatment. The "safe" treatment is recognised to be 25 mg prednislone, 75 mg aspirin and 400 mg progesterone. Oh, and when you get your results at the ARGC they push you really hard to have the IVIG treatment which is unproven and HUGELY expensive (I spent over £20k there on one IVF treatment where I miscarried, albeit due to chromosomal aneuploidy). If, I'd just used steroids, I could have shaved £8k off that bill.
It is probably too late for me know as I am nearly 44 yo but it is immensely encouraging to see that Dr Siobhan Quenby is offering that trial in Liverpool now and I would strongly advise anyone who is is the higher numbers of misc (i.e. at least 5 or 6) to go for it. It is really, really, really hard and frustrating to get this treatment you need anywhere else in London and Shehata's clinic won't provide the emotional support which is vital if we RPL suffers are not to go completely mad with the stress. Don't be put off by what Dr Winston says in the press today, as the Hammersmith is notoriously conservative in its approach and geared more to research papers and surgery.
Incidentally, Raj Rai put me on the progesterone during my 8th pregnancy and although I still lost it, it lasted 5 weeks longer than any of my previous pregnancies. Again St Mary's is v. conservative and if you have the NK prob, you need at lot more than 400g once a day, i.e. at least 2-4 times that if you are not getting any other NK treatment.
I hope this post is useful to people and cannot stress stongly enough how important it is for you to be pushy and pursue the treatment you want. Don't be advised by these London hospital clinics or you will get nowhere (but they will still happily take you money - my consultant put me forward for ivf AFTER i'd already had 3 miscarriages when the correct approach would have been a specialist repeaat miscarriage centre, but of course they don't get paid to make that referal). What did I know back then, 6 years ago?
I now need to have donor egg and NK treatment (2 x the stress, anybody?), so please don't ignore this advice if you have had a lot of miscarriages.