Sorry, this might have been asked before but I'm 48 and started HRT 3 weeks ago. I really haven't stopped crying since, am anxious and irritable. I'm going to ring the GP this morning and request a call as I just want to stop it. I'm already on sertraline for years but feel this is undoing everything. Has anyone had a reaction like this? I'm on oestrogel and progesterone tablet. Thanks, feel like I'm losing my mind