Thanks everyone for your replies - you've all been so helpful, and I really appreciate it.
Holly - thanks. I am accepting all the invites I get although I was pretty tied to the flat we live in to start with so I wasn't getting out and meeting people. But, yep, will definitely do that. Have to be honest and say I'm not too good at inviting myself to stuff, but know I need to work on that.
mummytime - I've not really experienced the church influence as yet. I lived in a few towns in the UK but there's just more around because the UK is (obviously!) so much smaller. The town I come from was smack bang in the middle of the midlands, so I could get pretty much anywhere, and I liked that. In comparison, I do feel out in the sticks a bit. I knew it was going to be different, and was open to it, but it is not something I particularly enjoy. As for moving (and I know dreaming and hop covered this too): I have discussed this with my husband as I would like us to be open to living elsewhere (closer to Columbus, for instance). Initially, he was very against this, but I think (although we haven't talked about it for a while) he was coming around to the idea that there is more to consider than just him - he got very used to that when he was single, so it's an adjustment for both of us. We have also discussed the fact that we may have to move back to the UK at some point depending on what happens with family, etc., but I guess I wonder if that will happen. He's not lived outside of Ohio, so not sure about how he'd feel when it actually came to moving.
Sittingbull - I wonder if there are any new people here! And, if so, I'm not sure how I'd find them. There doesn't appear to be much social activity going on here, so it's difficult to know. I know I need to look into this more - I was a bit discouraged when I looked at meetup and found the closest things were all in Columbus, which is not far but not that close either!
Hop - know what you mean about Chilicothe! I live closer to Columbus than that, thank goodness, but really wouldn't want to live there (and don't want to offend anyone with that - just not for me).
Natasha - definitely will.
Anewstart - I know what you mean about your 'real' friends. I have a best friend over in the UK and I wonder if I'll find anyone like that here. The people I've met so far want to hear my accent but not anything else about me, which I find frustrating. The whole 'oh, your accent sounds great, I could listen to it all day' thing has gotten old for me too. And, don't get me started on the healthcare issue! I hope your return back to the UK goes really well.
dreaming - I know what you mean being miserable. I don't want to be miserable, but I feel a bit trapped at the moment as I know that we can't move out of Ohio anytiime soon. I'm not trashing Ohio, but I think there are other places to explore. Have to wait and see what happens in the next year or so.
Thanks, everyone, for your responses. It's been great to hear that I'm not the only one having an issue, and you've given me lots to think about!