Please or to access all these features

Infertility

Our Infertility Support forum is a space to connect with others in the same position, discuss causes, treatment and IVF, and share infertility stories of hope and success.

Anyone starting IVF soon? Join me.

999 replies

Shellster52 · 06/03/2014 03:35

After 3 full failed IVF's last year, I am about to embark on my second last attempt. I started an IVF thread during my last IVF, and everyone got pregnant but me. So I swore I wouldn't do that again this time. But I find myself wanting to chat with people going through what I am, so I am starting the thread again. Join me as I seem to be a BFP magnet!

OP posts:
happylass · 08/09/2014 17:09

Hi all. Would you mind if I joined in please? I'm 36 and we've been TTC #1 for just over 2 years. Got married 3 weeks ago and after a lovely honeymoon it's now down to business! Have a baseline scan tomorrow ready to start our first cycle of short protocol ICSI as DH has antibodies in his sperm which make it more difficult although apparently not impossible to get pg naturally. We are going down the private route this time as we are on the NHS waiting list but its 18 months long here and at our age I don't think we can afford to wait. Wishing you all good luck with whatever stage you're at - ill try to get up to speed with the thread as soon as I can.

purplemeggie · 08/09/2014 19:52

Hello, Happylass - do come and join us. We're a mixture of old-timers and newbies, so hopefully someone to understand and empathise with all aspects! Good luck with the baseline scan....and the journey overall.

Noooo, Shellster - that's really bad news - so sorry. I can so sympathise with the "everyone else can do this, why can't I?" sentiment. My BIL and his wife had their second baby last month (their first was born on the due date of the last one we lost, which was also really hard) - and have done nothing but complain about how hard it is having a newborn and how she doesn't sleep....I know it's hard, but I really don't want to hear it at the moment! One of my colleagues announced her pregnancy today....oh, and William and Kate to boot, so there will be baby talk on the news for the next six months, too!

None of this is particularly helpful - just keeping my fingers crossed that this cycle isn't a write-off for you. It's just too cruel. xxxx

Shellster52 · 09/09/2014 05:27

Well the nurse phoned and just said to keep injecting and come back Thursday/day 9 for review. But actually Purple, I will be much happier once this cycle is officially written-off so I can finish grieving and move forward. As Blue says, I know going ahead this cycle will be a waste of $$$. By Thursday, the 3 biggies will be over mature and the smaller ones won't have grown. I know my body well by now so surely they will have to cancel me then.

Your logic makes sense Blue. I can learn from my failures and perfect things for next time. But this is my 8th IVF and I am running out of ideas! I actually got 5 eggs the first time I tried estrogen priming protocol last year when I only started with 8 follicles when I was on Puregon alone. Since then I start with 15-19 follicles but less eggs and have been adding Menopur. So now wondering if this isn't helping and I should not take it? Actually found a research article online last night showing Menopur is better at producing a single dominant follicle. Not sure if this is my problem since I am also taking Puregon, but I am going to ask to just take Puregon next time and hope this is the difference.

I am planning on having a one cycle break for ovaries to recover, start estrogen day 20 the following cycle and then IVF the cycle after. So starting late November just in time to have a melt down before Christmas. Really hoping my theory is right and I get more eggs but there are no guarantees so it's going to be a long anxious wait.

Hi happylass. Sorry to welcome you with my long IVF rant. What a way to start a marriage - the roller coaster of IVF. Hope it goes smooth for you.

OP posts:
bluemoonday · 09/09/2014 14:37

Hi Shellster. I was intrigued by your problem so I did a bit of googling on your behalf.....yes I am addicted to google, and yes I need a distraction from my hellish 2ww!!

It does seem as though your issue might be related to medication. How frustrating. I found this post about dominant follicles online - www.fertilethoughts.com/forums/ivf-and-high-tech/709750-any-success-after-cycle-s-dominant-follicles-what-changed.html

And I thought this article was interesting regarding 'types' of follicle. I wonder which type yours are? I hadn't heard of this before
radiopaedia.org/articles/follicular-monitoring

Anyway probably not particularly helpful but I do hope you are able to find a way to salvage this cycle, instead of having to start again from scratch.

Shellster52 · 09/09/2014 19:33

Well it's 4.20am here and I can't sleep. I still have that gut wrenching feeling in my stomach. So I thought a vent here might help. Blue, that is so very sweet and kind of you t be researching for me. I did actually find that first website myself in my search for answers. The woman is complaining about a dominant follicle - Not sure if it gives you any ideas about what medications cause dominant follicles, but I don't seem to be able to get any answers from it though to help me fix this problem for next cycle.

The second article says that once a dominant follicle is decided, it suppresses the growth of the other follicles. That confirms what I think I will see at my ultrasound tomorrow - the dominant three that were already mature at day 6 will be over mature and the little couple won't have grown. Hoping I'll feel better once I get that confirmation and can finish processing the loss of this cycle and start moving forward.

Blue, I've lost all track of your dates. What day are you at? When are you officially testing? Thank you again. The support on here means so much.

OP posts:
EmmaGH · 09/09/2014 19:47

Hi everyone! I've missed so much while I've been gone!! The holiday was excellent, however: really relaxing and a marvellous way to press the reset button (desperately needed, I might add).

Anniehoo and happylass (congratulations!), hallo! I am a relative newbie as well, as I've only had one IVF cycle. Good luck starting the process! I found it both hugely stressful and relieving. It was nice to have someone else take control over making sure the sperm and egg were in the right place at the right time. (Having sex for pleasure rather than purpose?! Heavens!)

Shellster, what frustrating news! It's so hard when you know your body, but feel you have to trust the professionals (and even harder when you're pretty sure they're making a misstep). I've got my fingers crossed that they are right this time and you're growing some excellent quality eggs.

Blue, I was thinking about you on my way home and wondering how far into this round you've got -- how are you feeling this time round? Any different? I would find it so hard not to analyse every twinge! I hope you're succeeding in letting them pass unnoticed. Thanks for the links, too. Very informative.

So far being fibroid-free is significantly better. AF descended the day after we arrived in Costa Rica, but, admittedly with the help of a little tranexamic acid, I was able to travel from San Jose to Cahuita on the Caribbean coast with no disasters -- that's a FOUR-HOUR bus ride! My last cycle I couldn't have taken a twenty-minute bus ride across London. I still had two sleepless nights, but that was born of being in a B&B and not wanting to have to explain any accidents to the owner! I understand it takes a couple of cycles to regulate, so it's possible it will get even better!

Purple, let's health-kick together!! After two weeks of taking advantage of Happy Hour whenever it was on offer (re: every night), I really need to get myself back on the health wagon.

A belated note on the swimming controversy: King's didn't say anything about swimming pools; in fact, they were keen for me to continue swimming once the initial two weeks were up. Perhaps I misinterpreted them, but it seemed to me they figured the exercise, plus the meditation it provides, would be beneficial. I'll ask about this properly, however, when we're next there.

Carrie, I'm so sorry to hear your news, how are you feeling? The post-cycle hormone crash is vile, but I hope you've been able to take some time to grieve and be kind to yourself. Be selfish, yes? Whatever you do right now is the right thing to do if it makes you feel better. (Except for crack. I'd avoid that.) Seriously, though, making yourself a priority is likely what you need most right now.

On our front, besides the holiday, there's nothing to report. We don't have our follow-up appointment with the NHS consultants until 3 October, so we're basically kicking our heels till then. I think this cycle is probably a write-off, too, despite having been on holiday. We managed to time it so that I likely as not ovulated on the plane or as we were going through customs -- and although there are ways of circumnavigating that particular obstacle, for the good of our fellow passengers, it was probably best that we didn't.

bluemoonday · 09/09/2014 21:20

Hi all, Emma, good to see you again. Glad you had a nice holiday, Dominican Republic sounds fab.

My official test date is this Friday.... I'm going for a blood test at the hospital. Very official - I just had to pee on a stick last time. Anyway I've decided to POAS Thursday morning because I can't stand it anymore... I'll be 9dp5dt be then so surely I'll get a proper result. I'm not feeling very hopeful. I've been getting twingy cramps for the last couple of days, feels like AF is on its way. Progesterone is making me feel really fed up and sad too... not helping!

Shellster52 · 10/09/2014 10:02

Emma. Your back! Hello :)

Oh Blue. I really had high hopes for you - You seem to make such good embryos and if one implanted last time and you had two this time, surely I thought it would work. Do you recall those twingy cramps last IVF or are they typical before your period arrives?

Just have this crap on my mind so wanting to post. No new news at my end though. I have a scan tomorrow morning so will have an update then. Really not wanting to go to EC this cycle knowing that the first few follicles to mature are the ones that your body is naturally trying to select and contain the best egg but mine are all overmature. So just hoping none of the littlies kept growing so they have no choice but to cancel me.

OP posts:
bluemoonday · 10/09/2014 14:08

Hi all - bad news from me. Period started today, I hoped it was just spotting but no...definite full flow. We're really disappointed. I had a feeling this has happened though - I've just felt 'normal' for the last few days, not bloated, cranky or pregnant in any way. It's frustrating. I guess it was an implantation problem again - everything else went well during the cycle.

Need to decide whether to try again straight away on the next cycle or take a month off. Also need to find out if there's anything we can do to mitigate against implantation issues. Going to the hospital for blood test on Friday morning so I'll ask some questions. Consultant seemed pretty unfazed last time, as though everything had 'gone well' and I shouldn't be worried about anyway. Well....now I am worried!! One chemical preg, one failure.

Anyway - sigh.

purplemeggie · 10/09/2014 17:11

Oh Blue - so disappointing. Sending a big hug. If it's implantation, might be worth seeing if your clinic offers this?

Emma - holiday sounds amazing - I'm glad you got to let your hair down. Your post made me laugh out loud - not something that happens very often on this thread!!! Yes to supportive health-kicks Smile. I've been SO saintly and good for the last week, it has to have had some effect.

So, I'm back on the rollercoaster. I called the clinic to make plans for the next cycle -starting short protocol after next AF - and I've just picked up my meds for endo-scratch on Friday. I'm expecting AF on 23rd September, so it's coming round quickly...

ireallyshouldgeton · 10/09/2014 21:31

Hello can I join?

I start down reg injections tomorrow for my frozen cycle. I have one child from our successful fresh cycle. Fresh cycle was short protocol so no down reg with injections. I'm not looking forward to being a pin cushion again but keen to get started. We tried to do a frozen cycle with just tablets recently initially but they didn't stop me ovulating so we had to abandon that cycle.

All being well this time, ET will be around 6th-13th October!!

Sending lots of luck to everyone on here!

EmmaGH · 10/09/2014 22:42

Blue, I'm so sorry, that's so disappointing. How are you coping? I really thought it was going to work for you too. It's great that the cycle itself was good, I'm just so sorry it didn't work. I hope you can take a few days to be with Mr Blue. Look after yourself. Heaps of hugs xx

Purple, I have saintly ambitions, but I discovered that the caramel chocolate Rice Krispie Squares contain no gelatine or eggs and are vegetarian friendly (but contain milk), so I'm afraid I had a bit of a bad-vegan day... I was doing so well, too. Tomorrow, I swear I'll start right tomorrow. Good luck on Friday!

Shellster, all fingers crossed for tomorrow. I hope it goes well!

ireallyshouldgeton, hallo! It's really rather lovely to hear success stories! Do you have a few frozen embryos? I hope it all goes well this cycle!

bluemoonday · 11/09/2014 12:26

Hi all - thanks for the good wishes. I'm ok. Disappointed and a bit fed up. Just to add insult to injury, AF is really heavy and gross.

Shellster let us know how it goes today.

Purple thanks for the link to the embryo glue. I'll mention it to my consultant - however, Prof Robert Winston (my favourite IVF scientist) thinks it's a load of rubbish
www.genesisresearchtrust.com/Blog/womb-scratching

I really like Prof Winston's blog. His advice seems very sensible and rational to me. I wish he still did IVF treatment!

purplemeggie · 11/09/2014 22:27

Hi Blue - the stuff I linked to isn't embryo glue, it's an alternative growth medium that they culture the embryos in for women who have had implantation failure/mc. Might be worth asking about it? My clinic doesn't offer it as standard, but sometimes the embryologist recommends it - I haven't been able to get to the bottom of why. Prof Winston is a bit of a legend, isn't he? I know someone who was lucky enough to be treated by him, 16 years ago, resulting in twin boys.

What's the news, Shellster? Hoping you're okay.

Welcome, Ireallyshouldgeton - we'll be doing EC/ET around the same time, I think, as I'll be on a short protocol, so I'll catch up.

I was thinking that I'd get a lie-in tomorrow as I normally get up at 6 to go to work and I'm working from home tomorrow because of having my scratch. But no - clinic phoned to say I'm scheduled for 7.30 and it's nearly an hour's drive, so it's going to be early o'clock!

Shellster52 · 12/09/2014 03:04

So very warm and welcoming to not post yesterday and to log in today and find you asking about me. I can't express enough how supportive you guys are.

My scan was a bit bizarre. Here's my day 6 and yesterdays (day 9) results so you can see what you think:
Day 6: 19, 17, 15, 14, 11, 8, 7 and two small follicles not measured.
Day 9: 26, 11, 11, 10, 10, and four small follicles not measured.
It isn't possible that the follicles have reduced in size!?!?

So I no longer have the concern about all my follicles being over mature, but I am just concerned about the low numbers. EC is the big cost for me and wondering if it is worthwhile for just 4 eggs at 10-11. Don't think the 8 and 7 will catch up (based on IVF history). Wondering if I should continue. If it were free, no probs, but at $6000 for 4 eggs?

I usually start with 15-19 follicles at day 2 but this time I didn't have a day 2 scan, and due to a cyst found on my day 6 scan, I only have 9 follicles. So I am sure if I tried again, I could have 15-19 follicles instead of the 9 I have this cycle and therefore get more mature eggs. On the other hand, if I cancel, wait for my body to recover, down reg and try again, my eggs are only aging and at 37, time is against me.

Having a repeat scan Monday. We shall see. Sorry for the long post. Just wanting to give you the details as any objective opinions are welcome instead of my irrational emotional roller coaster IVF thoughts.

Blue. I am shocked. I was even preparing myself for you BFP as I opened this thread. I just don't understand how two perfect embryos that make it all the way to day 5 don't implant. I recall you had a fibroid removed before your first IVF. Does that leave any scarring or anything that could cause issues? Did they ever mention any concerns about your lining during your scans before EC? Do you know how thick your lining was on the day of trigger? I read that a lining of 9 or 10 to 14mm correlates with optimal implantation. Just trying to come up with answers for you. Or at least questions for you to ask. I know how painful failure is and desperately want you to find an answer.

Purple, so your turn for the emotional roller coaster is coming around!

Ireallyshouldgeton welcome. I am rather jealous that you had success with your fresh cycle and even have embryos frozen for number two. I am on my 8th IVF attempt now and not a hint of a BFP! Best wishes.

Emma, you sound very healthy generally with your vegan diet so I wouldn't be too hard on yourself for one treat that you love. We have to live life in amongst all this crap. I was being very good but after my day 6 scan, I felt it was game over and ate hungry jacks twice, even adding bourbon to the coke one time! Now the clinic has me continuing on!

OP posts:
Shellster52 · 12/09/2014 07:16

Oops, I wrote don't think the 8 and 7 will catch up. I don't even have 8 and 7mm follicles based on my latest day 9 scan. I was looking at the day 6 scan results. Going a bit loopy with all this!

OP posts:
ireallyshouldgeton · 12/09/2014 07:56

Shell - I really truly hope you have success this time. I do actually know sometime IRL who did finally conceive (twins!) on her 8th cycle so keep hope, as hard as it must be. I admire your determination to keep going. x

ireallyshouldgeton · 12/09/2014 08:10

purple - hope all goes well!

bluemoonday · 12/09/2014 10:29

Shellster so the story continues! What a drama. Given that you got so many follicles last time I can understand why you might want to cut your losses with this cycle. Is there any correlation between #of follicles and egg quality? I have no idea. Just wondering if a lower number of follicles might produce better quality eggs, albeit a lower number of eggs overall?

I'm not sure if if be prepared to take the risk in your shoes given the ££ involved. Yuck.... I hate these horrible IVF situations. I hope Monday's scan will give you enough info so you can make a choice you feel happy with.

Thanks for all your support everyone. I had an appointment with my nurse this morning and she got all teary eyed... she was convinced that out of all her 'ladies' i'd be the one with a bfp this week! Didn't know whether to laugh or (join her and) cry. She recommended we try again. Everything went well... Shellster my lining was 11.9 so apparently good. No scar tissue either.

purple thanks again for the link, that is really interesting. I will discuss it with the consultant when we see him soon. Yes, I really do wish Robert Winston was still offering IVF. He's my hero!

Good luck and hello everyone else. Can someone PLEASE get a BFP soon, we are overdue some good news on this thread.

ireallyshouldgeton · 12/09/2014 10:40

Blue - I understand that there is a correlation between number of follicles / eggs and quality. My clinic on my fresh cycle were v clear on that.

purplemeggie · 12/09/2014 11:21

Shellster - I agree with the ladies above, and it ties in with what my clinic said about egg quality, too: I had five good-sized follicles, and I was really disappointed, and the sonographer said "I'd rather see five good-sized follicles here than 20 small ones any day". If it were me, I'd go for it. Although you've had cycles where you've had more follicles, you've also had a lot of cycles where you have had to abandon the cycle before EC and five is okay. Even allowing for normal fertilisation stats, you should get at least 3 fertilising and that's not to be sniffed at. And even if the EC is the biggest single outlay, if you add together all of your abandoned cycles, doesn't the cost mount up? So hard to know what is best though, and I feel for you having to make difficult decisions.

Had my scratch today. Hurt much more than last time, but they do say it needs to, don't they? Ho hum.

purplemeggie · 12/09/2014 12:58

Blue - a thought occurred to me today that my consultant was talking about screening for clotting issues and immune problems as I have had failure to implant with two good blastocysts - I wondered if you might benefit from the same screening? In fact, my gp had already done lots of tests before referring me, as my mother has a clotting disorder which contributed to her (4 Sad) MCs. The consultant is considering whether he should prescribe heparin for my next cycle and has already recommended aspirin, which I have been taking for the last month.

djasmin · 12/09/2014 16:21

I need help with finding medication.I am starting my IFV with egg donation in about 10 days and I need to stat my medication on day 2 of my period which is probably going to be on sunday or Monday.
However there was a misunderstanding between my clinic abroad and the online pharmacy and now my medication can not be delivered to me until Tuesday.I was crying when I found out as now it's going to mess up the whole treatment so I would like to ask if someone has Progynova tablets 2mg and Folic Acid tablets 5 mg that I can buy from you urgently.
I live in London and will travel anywhere in London to collect them.
Many Thanks

EmmaGH · 12/09/2014 19:18

Purple, when are you to take aspirin until? The whole cycle or just until EC? I'm very curious. I'd like to test drive using aspirin on a non-IVF cycle and see if it works at all.

Shellster, I'm quite sure that there is a correlation between quantity and quality. I know my consultant was delighted that we had eleven but indicated that any more would have compromised the quality of the rest. It's possible he was being particularly enthusiastic in a very odd way to keep my spirits up, but I do tend to think these few follies of yours have had all of the nutrients and all of the goodness your body has to offer. If you still have six biggies by EC day, I think you would be in a good position. I hope you're able to make a decision you're comfortable with -- not an easy ask, though.

Blue, your consultant sounds really lovely! When we have our next appointment, I'm definitely going to ask if I can arrange to have a lining screening as I approach ovulation to make sure it's thick enough. If it's not, that could be the reason we're having so much trouble. I like Purple's suggestion, too, about immunisation screening. If you are allowed it at Guy's, I'm sure I'd be at King's -- they're part of the same borough, aren't they?

DJasmin, I'm really sorry, I can't help. Fingers crossed you get lucky!

ireallyshouldgeton · 12/09/2014 22:06

Emma - I had my fresh cycle at King's! I found the ACU there just fantastic! We're in another part of the UK now so couldn't manage the logistics of doing an FET cycle
at King's unfortunately. I just
don't feel so confident with our new clinic, but I'm not sure why. It all feels different now that we're paying ourselves... But we have a v limited choice in our area so that's that.

I know quite a few people who had
successful treatment at both
King's and Guy's btw.