Oh that must be so difficult for you as well as for her.
A few things that might help -
The Uni will have a welfare section, and people will be looking out for freshers who are overwhelmed by it all - make sure she knows they are there for her.
Also, there will be chaplains - whether your daughter has any faith or none, they are there to help 'look after' all of the students, and are likely to also be providing quieter places to stop and chat over a coffee, see a friendly face, talk about things that are bothering them.
There will be a chance to see all the societies on offer and maybe sign up for them - if she's not into drinking/clubbing then this is a great source of like-minded people, as she can join up for a sport, or chess, or conservation volunteers, or whatever.
And the people on her course being unfriendly - more likely they are all also nervous and tense and not giving off 'cheerful and friendly' vibes, but that will settle down when they get a chance to know each other.