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Fluoxetine side effects

8 replies

Booklover88 · 04/10/2025 10:12

Hi, sharing looking for positive stories!

I went on fluoxetine about 18 months for PND when DD was about 4 months old. Side effects were awful for the first few days but after a month, I was feeling pretty good and it ended up totally changing my life.m

I only came off it earlier this year to try for another baby but after about 4 months of being off it, I realised I wasn’t coping as well so two weeks ago, I started taking fluoxetine again.

First week was fine- bit nauseous and waking early but nothing major. Brain fog felt like it was lifting and I was feeling pretty good, enjoying life again.

Now on day 15 and the last three days have been terrible. Chronic insomnia (waking at 1am and not going back to sleep), panic attacks, anxiety, tearful and no appetite at all. I know it gets worse before it gets better but it’s caught me off guard as the first week was ok! I really want to persevere with it as it was so amazing for me last time but I thought side effects were supposed to tail off after two weeks not get worse! Any wise words appreciated

OP posts:
SexRealist20 · 04/10/2025 18:36

What is making you unhappy?
is the sex with your bf one sided?
Imagine treating him like he treats you, would you be horrified with yourself?
Did you want a better career?
Are you sick stuck in looking after a baby?
Do you need more breaks?

Most women with depression are just actually oppressed by their partners

Booklover88 · 04/10/2025 19:32

My husband is incredible and could not be more supportive. Nothing is ‘making’ me unhappy- that’s not how mental health works.

OP posts:
PauliesWalnuts · 04/10/2025 19:35

SexRealist20 · 04/10/2025 18:36

What is making you unhappy?
is the sex with your bf one sided?
Imagine treating him like he treats you, would you be horrified with yourself?
Did you want a better career?
Are you sick stuck in looking after a baby?
Do you need more breaks?

Most women with depression are just actually oppressed by their partners

Oppressed by their partners?! What a load of shit. I’ve been single most of my adult life so where’s my depression come from then?!

Oaktreet · 04/10/2025 20:00

SexRealist20 · 04/10/2025 18:36

What is making you unhappy?
is the sex with your bf one sided?
Imagine treating him like he treats you, would you be horrified with yourself?
Did you want a better career?
Are you sick stuck in looking after a baby?
Do you need more breaks?

Most women with depression are just actually oppressed by their partners

I've also experienced depression in the past and have a very supportive partner.

It's good to try and understand if there's anything causing depression but depression is highly complex and the cause can be many different factors and multiple factors at the same time.

When I had depression, I lived healthily, had a good social life, a supportive partner, there was no obvious reason as to why I was depressed, yet I was.

In response to your post OP, I would speak to your GP (because I'm not one!) and just see where you are in a week or two's time because I've heard it can temporarily increase symptoms when you first start taking it and it worked for you before.

If you ever want to come off the medication in future I would refer to a website called "surviving antidepressants". Many people have difficulty coming off antidepressants, with symptoms returning because they tapered off them too fast and experienced withdrawal. Unfortunately GP advice on how to taper off is not accurate and they advise coming off them far to rapidly, which can lead to a return in symptoms.

Booklover88 · 05/10/2025 08:13

Oaktreet · 04/10/2025 20:00

I've also experienced depression in the past and have a very supportive partner.

It's good to try and understand if there's anything causing depression but depression is highly complex and the cause can be many different factors and multiple factors at the same time.

When I had depression, I lived healthily, had a good social life, a supportive partner, there was no obvious reason as to why I was depressed, yet I was.

In response to your post OP, I would speak to your GP (because I'm not one!) and just see where you are in a week or two's time because I've heard it can temporarily increase symptoms when you first start taking it and it worked for you before.

If you ever want to come off the medication in future I would refer to a website called "surviving antidepressants". Many people have difficulty coming off antidepressants, with symptoms returning because they tapered off them too fast and experienced withdrawal. Unfortunately GP advice on how to taper off is not accurate and they advise coming off them far to rapidly, which can lead to a return in symptoms.

Thank you for your kind words. I’m going to give it another week and if the side effects are persisting, I’ll speak to my GP. I did manage a little more sleep last night and the anxiety doesn’t feel quite as crippling today so progress!

OP posts:
MarmadukeM · 05/10/2025 08:27

I’m not on fluoxetine but i recently started Vortioxetine and if it’s any consolation have felt pretty much the same. It was insomnia, night sweats, poor appetite and a jittery feeling. It took about 2 to 3 weeks to settle, the sleep never really improved so I now have mirtazipine 15mg as well for sleep and that worked immediately. Hope it levels out for you soon xxx

Midnightlove · 13/10/2025 21:34

SexRealist20 · 04/10/2025 18:36

What is making you unhappy?
is the sex with your bf one sided?
Imagine treating him like he treats you, would you be horrified with yourself?
Did you want a better career?
Are you sick stuck in looking after a baby?
Do you need more breaks?

Most women with depression are just actually oppressed by their partners

Oh do shut up. You sound like a nut job

Mulledjuice · 13/10/2025 21:35

I suspect that first poster is responding to the wrong thread.

Is it possible you are experiencing perimenopause rather than side effects?

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