self-managed for yrs, st john's wort etc and finally turned to ads (citalopram) and I think it's working! Hope i'm not speaking too soon (2 1/2 weeks) but I@m so grateful. My black cloud now merely hovers and then abates, I actually feel postive much of the time, i'm seeing things in perspective... Of course the weather etc helps but the pills have too. Just wanted to share the good as well as the bad times (which i've often inflicted on Mners.. ). Hope this may encourage and help someone else.