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Mirtazapine and weight gain

4 replies

StrugglingAsAlways · 14/02/2025 19:17

I was put on Mirtazapine just before Christmas. Citalopram just wasn’t doing its job so I’m reducing that and on 15mg Mirtazapine Dr wants to increase Mirtazapine to 30mg. Problem is I’ve gained 7lbs since I’ve started this drug and the hunger is awful. I’m trying to eat foods which fill you up and healthy foods but nothing helps. I’ve asked the doctor for an appointment to discuss but he can’t phone me for another two weeks. Does the weight gain plateau? I really don’t want to gain any more weight as I’m probably about two stone overweight as it is.

OP posts:
StrugglingAsAlways · 14/02/2025 20:26

Bump, anyone please? Should I just stop taking them or wait and speak to the gp?

OP posts:
Baguettesandcheeseforever · 14/02/2025 20:29

I’ve been on it for 4 years now - 45mg and my weight is just going up and up regardless of how much it b little I eat. I don’t know what to suggest… just showing understanding, I suppose. But, it has helped my anxiety significantly so I’d rather be heavier and more able to function so I just keep reminding myself of this.

Gogreengoblin · 20/04/2025 13:05

Sorry to re-awake this thread, but at least it's not too old:
I take mirtazipine (and quetiapine) myself and I am aware of it's reputation for weight gain, I was told by a medical professional 2 days ago that it changes the way the body metabolises fat and I'm fed up of being the weight I am.... I am no longer gaining luckily, and luckily my appetite plateaued over half a year ago, BUT I am not losing weight after adjusting my diet considerably.
I have asked google but not enough info is available to answer my question of if I reduce the dosage (with the permission of the psychiatrist prescriber), will it be easier to lose weight?
I do need both of those medications, but they increased them with the intention of them helping me sleep, which they don't, but they help me in other areas psychologically which I can't fo into.

Superscientist · 22/04/2025 10:44

Gogreengoblin · 20/04/2025 13:05

Sorry to re-awake this thread, but at least it's not too old:
I take mirtazipine (and quetiapine) myself and I am aware of it's reputation for weight gain, I was told by a medical professional 2 days ago that it changes the way the body metabolises fat and I'm fed up of being the weight I am.... I am no longer gaining luckily, and luckily my appetite plateaued over half a year ago, BUT I am not losing weight after adjusting my diet considerably.
I have asked google but not enough info is available to answer my question of if I reduce the dosage (with the permission of the psychiatrist prescriber), will it be easier to lose weight?
I do need both of those medications, but they increased them with the intention of them helping me sleep, which they don't, but they help me in other areas psychologically which I can't fo into.

I've been on quetiapine for 12 years and occasionally been on mirtazapine for months usually once for 2 years.
They were broadly weight neutral for me and after I had my daughter on both and a very restricted diet I actually lost quite a lot of weight and ended up very underweight.

My understanding is quetiapine has an impact on metabolism but it also can make you crave fatty foods. I know this can definitely be the case for me.

I was on lithium as well as quetiapine and mirtazapine for 2 years and that definitely resulted in weight gain within in 3 months of being on it I went from very underweight to average again although this did also correspond with my diet going back to normal. I then gained more weight and it was hard to get it off again until I stopped the lithium.
With age, especially around 30 and then 35 I've found it harder to reduce my weight when wanting too.

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