Sertraline causing Damage?

[JoeyLin]

Hi, my 60 year old mum has been on sertraline for over a year (increasing from 50 - now 200mg).
Each increase gives a short lived boost before going backwards.
Also in this time, her depression has become pychotic depression - more pacing around, anxious, phobios to leave house or answer phones. She is now on Olanzapine , 10mg.

Doctor has finally said maybe Sertraline is not for her.

Questions -
Could Sertraline be causing the negative anxious effect on her behaviour (whilst its obvious its doing nothing for her depression)

Dr mentioned a switch to SNRI tablet... has anyone had gone through a similar pattern where Sertraline didn't work, but something else did?

Also worried about the year now causing permanent damage IF Sertraline was making her worse.

Hi JoeyLin. I was on sertraline for a few years but eventually ended up really anxious/some very odd thoughts (people were telling me to kill myself with their eyes)/and very low in mood but at the same time totally wired, not sleeping etc. It was horrendous. The effect wasn’t permanent. I was put on different drugs including a SNRI. It took quite a long time to be “functioning” as a human being though…a few months? As in not cured, or at work, but able to do day to day basics. So yes, it is possible to find improvement on other things.