I have been tapering down my sertraline for 3 months and after a month on 25g every other day took my last dose on mon/tues last week. Been fine then on tuesday I had the most overpowering sadness and anxiety all day - I felt almost like I wanted to give up. I often get a day or 2 of this around a week before my period, so thought it might be that. But the anxiety has persisted - tight throat and chest, almost can't catch my breath, intrusive negative thoughts and overall sense of DOOM. Work has been stressful this week - I've made a few small mistakes - well, not mistakes exactly, but where I havent done things in the way my boss wanted me to (I'm in a senior position in a new job). And I can't stop thinking that maybe they are regretting hiring me, that I'm failing, its all too much etc. I havent felt like this since before sertraline (over 2 years ago). I love my job and my bosses have been nothing but supportive. What's happening to me?!