I’ve been on a 45mg dose of mirtazipine and a 150mg dose of quetiapine for the last three years for depression, which I’ve had since I was a teenager and tried various medications for.
I’ve been feeling okay for a long time now, at least the last six months, but I was sleeping 14hrs at a time and I’ve put on over 3 stone, so I decided to talk to my GP about reducing/coming off them. I’m still under a psychiatrist but it works out that I see him about once every 18 months (he reschedules a lot). The GP couldn’t advise me about the quetiapine, apparently, but said I could break my mirtazipines in half for six weeks and come back and see how I’m getting on. I’ve been doing the same with the quetiapine.
It’s been, honestly, great. I’ve got so much more energy. The difference is incredible. It’s been two weeks since I started cutting down.
The only problem is that my joints have all started aching. My ankles, my elbows and the ones my hands mainly. My hands are puffy, but it could be the warm weather and the fact that I’m overweight.
Does anyone have any experience of something similar happening when they’ve reduced medication? I don’t know whether it’s a complete coincidence or whether it’s a proper thing. How annoying would that be, to finally be feeling better only for all my joints to give up on me? 
Thanks if you read all that