Anyone else with mental health problems feel lonely and have no friends?. I long for real friendship but don't seem able to commit to what other people want out of a friendship. Its not that im antisocial, im chatty and have 'acquaintances' but because of my depression and anxiety issues I make my excuses and turn down girlie nights out and general invites from people. This means people don't bother with me again or because they don't know me, get the complete wrong impression of me. All this makes me feel lower and my self esteem gets worse (if thats possible! ) and I get left behind and the loneliness snowballs. I long for a good friend. Is it possible???!!!.