Anyone have experience of the new antidepressant 'Agomelatine' ?

[JohFlow]

Hi All,

I am due a medication review and have read about a new drug that has come onto the market. It is classed as an antidepressant but mimics the natural-bourne hormone Melatonin (used as a regulator of sleep, appetite, waking, SAD symptoms, body temp. etc). Manufacturers are claiming that it has fewer side affects than other antidepressants, there is no loss in libido and it can help the body re-synchronise itself.

Sounds great to me.

But does anyone have experience of taking Agomelatine? How have you found it?

'bump'

Hi, I've been on it for 3 years - it is wonderful! No side effects that I've noticed and the longest time without being ill. It also starts working really quickly and prevents relapses. I LOVE IT

What did you try before?

I take it as well as Prozac but before I had mirtazapine which just stopped working (and made me massively fat and sleepy)

I've been on it a year and it turned my life around. I've got bipolar and all other antidepressants destabilised my mood and caused highs. Agomelatine has worked brilliantly with no side effects. Just a word of warning, though. I had a nasty relapse this summer while in the USA. The pdoc mentioned that agomelatine only works if you take it at night. Any other time of the day, it's like a sugar pill. He wondered if the jet lag meant my brain didn't register the agomelatine and that was why I relapsed. He wasn't sure, but it's certainly odd. Anyway, I love agomelatine.

Ps I'm in scotland, where it's not licensed with the NHS (ie it refuses to fund it normally). I was lucky to have a pdoc from England who didn't realise this when he prescribed it and my GP didn't pick up on it. I've subsequently had special funding approved from nHS scotland.

Excuse my typing. I'm on my phone.

Thank you for that Queen and Don't. I'm currently on Trazodone and have been for the last 12 years. I am finding that I am having gradually more relapses on it ; so think my body has built up a resistance. I also am becoming less tolerant of being so thick headed in the morning and forgetful generally.

Do you feel refreshed after a sleep on this. Are you wakeful during the day?

Yes, feel totally "normal" (whatever that is!) Mirtazapine stopped working for me - it was like I'd built up a resistance.Agomelatine is the best thing I've ever been on. Absolutely no side effects.

I took it for a little while, I can't remember why I stopped but it didn't suit me. I remember getting tingly nipples which was odd.
It seems to really work for some & not at all for others. Just a case of trying it. It helps with sleep if you have trouble sleeping.

No sedation at all. One thing is you need liver enzymes checking every few months or so. As post says above, it seems it either works brilliantly or not at all.

Yeah I guess I need to check its suitability for me. Thanks for your posts