I have been taking St johns wort for about 2 weeks now. I took 300 the first day, and built up over the next couple of days to 900mg. I have been getting quite bad persistent headaches most days now. Does anyone have any experience of this. It is working brilliantly for my mild depression, so it would be a shame to have to stop it now. Do you think the side effects will lessen soon, as it is becoming a bit annoying. Sorry as I write this I am thinking there people who are dealing with much worse than this on this forum, but if anyone has any experience of this I would appreciate the feedback.