I believe it is possible. Still early days for me, but so far so good. DC2 is nearly 6 weeks old.
I had a terrible time with DC1. REally bad PND. Hospitalised in a mother and baby unit for 3 months. I was on heavy duty medication for 2 years afterwards. Told I would be on medication for the rest of my life etc....
Well, it was a hard decision to try for DC2 but am sooo glad we did it. I feel compltely different this time round. Knackered, yes. But instead of dreading hearing my baby cry, and panicking about every little thing, I actually enjoy attending to my baby this time round. I realise that when you have bonded with a baby, all the chores and the mundane-ness of it all is SO much more bearable!
For me, what made the difference was first and foremost, having a better birth experience. I acheived this through hypnobirthing and practising relaxation tecniques daily during pregnancy. This meant I was much more chilled out. I had a much more straightforward birth and was home the next day. This compared with a horrendous first birth experience where I had a 9 day hospital stay.
Being home quickly meant I could sleep and relax in my own home again. Also the fact I didn't have drugs in pregnancy meant my baby was much more alert, ready to feed straight away. I was able to breastfeed, which I believe has really helped the bonding. Also breastfeeding makes you feel more relaxed because of the hormones it releases.
I am being monitored closely by the psychiatrist, and to be honest I DO have tearful days. But this is normal for any mum. I do not have the awful hideous anxiety, insomnia and misery that I had first time round. I just feel tired. But I enjoy spending time with my baby, and I realise how much I missed out on first time round.
I do think you can do a lot to help yourself avoid it second time round, I really hope it goes well for you x