Both on the level of my day to day existence and how i relate to people, and when i stop and think about the state of the world in general, really.
I've wondered over the years whether i have aspergers or what else could be wrong with me. I've struggled with depression on and off for lots of my adult life, I know that much. I just don't seem able to get along with anyone these days.
I know people will think i'm heading for another bout of depression when I say these things but I was watching that Evan Davies thing 'Made in Britain' last night and when he was gloating about the fact that we are now manufacturing these awful drones which don't even need to be remotely piloted; they're basically robots which are programmed to be able to pick out which targets to bomb for themselves, I just couldn't imagine how anyone could watch something like that and not feel utterly depressed. Especially when he's simultaneously talking about what a key industry it is for us and how we basically depend on exporting these machines in order to bridge the trade deficit! FFS!
And it's not just that, it's so many things... 
I must be mad cos it doesn't seem to bother anyone else.