That's it really. I haven't been on a bike in years, and found myself looking at one today. Tried one in a shop and was on it less than 5 minutes and my hands ache at the base of my thumb in the fleshy bit towards my forefinger. I remember this from my teens when I did last own a bike, and when I borrowed one for a day a couple of years ago.
Am I weird? The only bike that didn't ache was a 'sit up and beg' style, which isn't exactly going to fit in with my husbands idea of using a bike as a form of exercise.