Will they create a traditional vaccine as opposed to the mRNA?

[TheOldStar]

Does anyone know if there are plans to develop a traditional vaccine for covid? I think the uptake would be much higher if they did.

Traditional vaccines do seem to be more effective, the mRNA just seems to limit symptoms in many cases.

@Kokeshi123

The sino vaccines are a bit crap, but Valneva and Novavax appear to be good vaccines.

They won't win round the hardened anti vax conspiracy nuts, but will probably convince the kind of people who mostly do get vaccines but were hesitant about this one. And we should bear in mind that "hesitant" people are actually a lot commoner than "100% anti vax" people.

Yes, I genuinely think novavax will sway a lot of those who are hesitant about the current vaccines. It has also shown great results when used as a booster on top of pfizer/moderna, so I am really hopeful on that front too. Fingers crossed that an approval is right around the corner!

Gosh given the long covid stories I'd be more concerned about covid destabilising an auto immune condition than mRNA vaccines.

Thanks all, I’m going to get the novavax.

I’ve had covid and was fairly ill, although a lot of friends who’ve had the vaccine have had really awful side effects so I decided not to have it. My natural immunity will be waning soon so I needed to make a decision.

@PineappleMojito

Message deleted by MNHQ. Here's a link to our Talk guidelines.

@PineappleMojito I astonishingly had this conversation with a GP in the pub yesterday......

When I pointed out the complete absence of any genes and also nuclease (which allows the new genetic information to enter the nucleus) in the MRNA vaccine. He did to be fair shut up and apologise to the people he was talking to.

You get good doctors, bad ones and ones that don't really think outside their own speciality. You cannot practice medicine effectively unless you treat the body as a whole unit.

I'd get another consultant. And have your booster.

@BigGreen

Gosh given the long covid stories I'd be more concerned about covid destabilising an auto immune condition than mRNA vaccines.

Absolutely. I had covid in March 2020 and apart from how scary and awful it was, not including the need to use an inhaler, chest pain and ectopic beats for nine months, the aftereffects have been:

Massive Psoriasis flare all over my body.

Massive Psoriatic Arthritis flare including widespread tendinosis in shoulder, hip, spine, ankle and foot.

Developed antibodies towards my then biologic, meaning I'm now on one that costs the NHS thousands more every month.

Been diagnosed with celiac disease and must avoid dairy, wheat, gluten, barley and all oats for the rest of my life.

Oh, and I went from perfectly normal/healthy blood glucose, cholesterol and triglycerides a month before Covid to diabetic and high risk levels four months later. I'm due to have the tests repeated soon to see if it was common or garden type 2, but they are concerned it might be a sign of an autoimmune attack similar to type 1, so I am being more carefully monitored than the usual prediabetes 'try to lose weight and we'll retest next year'.

And I've found five new things I'm now allergic to that I never was before.

Correlation is not causation, but it seems rather convenient that my autoimmune issues worsened and began having dramatic effects upon other body systems in the months following covid infection.

Not had anything new following vaccination, though. Except well, you know, not catching the latest variants. And nobody needs the sensation of being slowly crushed to death for a fortnight, which is what covid felt like to me.

[quote EmpressCixi]@PineappleMojito
Message deleted by MNHQ. Here's a link to our Talk guidelines.

The Covid vaccine isn’t gene therapy at all. While using mRNA in a vaccine for a virus is new, the use of mRNA to fight off pathogens has been around for twenty years mostly as cancer immunology treatments. It’s a safety tried and tested technology being used in a new way, that is all.[/quote]
As I have posted elsewhere today, mRNA research has been going on in labs around the world for many years. The recently announced new treatment for malaria is an mRNA-based treatment. DD2 has a first-class masters in control of infectious diseases and her Masters research involved mRNA sequencing. It is neither new nor experimental.

All 4 members of family here have autoimmune conditions, all 4 have had 2 jabs + boosters, no discernible impact on any of our pre-existing conditions.

Many in my position who were told mRNA wasn’t the best option for us medically when this rolled out, now being told we have no other option. AZ off the table.

Not quite. We were told that it was best not to take it as, at that time, there was no reason to, AZ existed, and more research was needed to estimate a true RR.

The message has changed because so many people volunteered to take part in trials, data was taken from across the world and now, for many of us, the RR is better known and we are being told to take Pfizer, as I did this morning!

Novavax approved by the European Medicines Authority yesterday as expected.