People that had vaccine very early on...

[Bubbles2456]

I had my first vaccine in Jan, so am I right in thinking, my immunity to covid will be wearing off now?

@Bubbles2456

I had my first vaccine in Jan, so am I right in thinking, my immunity to covid will be wearing off now?

I had my first in Jan uary, 2nd 8 weeks later, and I know I still have antibodies because my blood gets tested for them very month. (ONS survey).

I was vaccinated end of dec. DP tested positive for covid last week, and although I had mild symptoms at the same time I've had several negative tests, so I'm assuming my immunity is still pretty high.

@Waxonwaxoff0

My mum had vaccine in January as an NHS worker. I had Covid 2 weeks ago and she didn't catch it off me even though she stayed overnight in my house and hugged me (without knowing I was positive at the time). Whether that's just luck, the vaccine or the fact that she already had Covid last year I don't know.

Same here, my son tested positive at the start of the school holidays, both myself and dh had our first vaccine in febuary and second in june, neither of us caught it off him, and i did hug him even when i knew he was positive.

@ActonSquirrel yes it existed! I was in the AZ vaccine trial

The covid vaccine existed in summer 2020?!

The Covid vaccine existed within days of the virus information being released in January. First trials started in March.

Med school rat, interesting theory.
I guess this theory works against kick downs etc then because we need the virus around to calm down and not get worried (reduced contacts) to get nastier..

?? If so how can virus be so clever and knows it's not infecting people?

Worrying stuff about immunity though?
Proper huge trials need to be done (I'm sure they are).
Flu vaccine wanes after about three months.

Re catching covid, before vaccines people commented on living with sick people and not catching it.
It seems so random?
Viral load? Where it was caught? Etc

Super spreader.. Hopefully we will get more definitive break through on it.

I vaguely remember the talk about Tcells last year. Does anyone know of any studies around this area? Can there even be any studies. I seem to recall it mentioned that it was difficult and expensive to investigate.

Lbnc2021 I hope your dad makes a full recovery.

I think antibody tests are useful because they give people a bit more information to use when calculating what risks they are comfortable taking. I'll be getting my groceries delivered and avoiding public places when possible. Now is not a good time to be adding to the strain on the NHS. I feel so sorry for all the hospital workers who are so stressed and exhausted, and having to watch the covid wards fill up again.

This is a useful read. And one that should reassure.

www.theatlantic.com/science/archive/2021/09/waning-immunity-not-crisis-right-now/619965/?utm_source=email&utm_medium=social&utm_campaign

People need to educate themselves more on how immunity works. There’s a lot more to it than antibody levels.

Me and Dh both had first dose in Jan, 2nd in April due to jobs. We're doing virus watch and ons each month and still both have detectable antibodies. We've not had covid and the virus watch results have said we have vaccine antibodies rather than exposure ones

I had my first early Jan. Second early April and caught covid end of July.

Why a weekly PCR?

@naynayisay

I had AstraZeneca (before it came out about the blood clot side effects & shouldn't be used in under 40's & before the efficacy statistics) and then my second in May because it hadn't come out again that you could have different vaccines for your first & second.

I'm assuming I have very little, if no immunity, at this point.

I had AZ at the same time as you. Like PP I’m also in a research study and I still have detectable antibodies due to the vaccine (and I’m a lot older than you).

@Bubbles2456

I had my first vaccine in Jan, so am I right in thinking, my immunity to covid will be wearing off now?

Do you mean you haven't had the second?

@BertieBotts

We don't know that the effectiveness wears off. We just don't know for sure that it lasts longer than X months because it has only been X months since the first people had it.

I think the reports of waning immunity are based on real world studies of who is catching Covid.

Recent Israeli data does show that protection against infection is showing signs of waning - based on who is catching Covid and when they had their vaccine. It’s not about antibody levels, and as already noted, there is more to immunity than antibodies.

Three things to note:-

1). Protection against severe disease and death does NOT show the same signs of waning (yet?)

2. Israel has started a booster campaign in older adults and a month on it is proving effective, i.e. people who have had the booster shot regain previous levels of protection. (12 days after seems to be the time)

3. Waning immunity in people who have had 2 doses does not necessarily mean annual boosters will be required. For example, tetanus requires a series of 5 shots, and hep B is 3. It could be that three shots (or 4, or 5) will then give immunity which does not wane…. or you need a booster every 5 years, or 10 years. It is still early days as far as longevity of immunity is concerned against this virus which has been in the human population less than two years.

Recent Israeli data does show that protection against infection is showing signs of waning

Recent thread on Twitter by SAGE member, why Israeli data are outliers and not the very best data to use for decision-making.

Waning antibodies do not necessarily mean waning immunity - you would expect this after any vaccine. Flu vaccines are repearted every year because flu changes so much, not so much because of waning immunity.

This twitter thread about the differences between male and female immune systems and response to vaccines is interesting and somewhat reassuring. It appears that women in general produce fewer antibodies and their levels drop more quickly when compared to men, but we tend to have a better T-cell response. twitter.com/ahandvanish/status/1387140392794079236

On the other hand the fact that women create fewer antibodies and loose them more quickly leads to "10-30% of "mild" infections accidentally being classified as negative" which explains why so many people on these threads are reporting their entire family being diagnosed with Covid and them being sick but repeatedly getting negative tests. Also, if a long covid diagnosis requires a blood test providing evidence of virus antibodies then a lot of women are going to be dismissed as hypochondriacs and excluded from appropriate treatment.

@Cookerhood

Waning antibodies do not necessarily mean waning immunity - you would expect this after any vaccine. Flu vaccines are repearted every year because flu changes so much, not so much because of waning immunity.

The data used for these studies was not antibodies but an analysis of who was catching the virus I think?

You can do an immunity test to check. I used Bio-Diagnostics Ltd which was a company suggested by mumsnetters as a good one to use if you are testing immunity after vaccines. My hubby and I both had 2nd jabs in june - his immunity has come back strong which is great - two jabs worth of immunity. Mine has come back moderate - one jab worth of immunity despite having had two jabs. I get these tests don't factor in T cell immunity etc but it is worrying considering I am in group 6.

@Bubbles2456

I had my first vaccine in Jan, so am I right in thinking, my immunity to covid will be wearing off now?

Why, in the name of everything holy, when the scientific world are openly saying they dont know, would you think that mumsnet knows the answer to this?

@Stealhsquirrelnutkin Where did you get the tests from? I'm in a similar situation to you with various chronic health conditions and typically rubbish immunity, so I'd really like to find out what my antibody levels are now (4 months after 2nd vaccine), especially with the winter coming up!

monitormyhealth.org.uk/covid19-vaccine-immunity-test/
£37 - the Roche Anti-SARS-CoV-2 S test