New Pfizer data - 98.9% effective at preventing death

[doireallyneedaname]

Fabulous!

yes by 'reports on here and elsewhere' I meant anecdotal reports of people getting it or knowing friends/families who got it, which of course will vary greatly in their reliability!! Not official reports of any sort.

But some people have definitely claimed to have had a positive test, over 4-weeks after the vaccine, and more than you might think given those data. Of course all those people might just be on Mumsnet and wanting to spread that news...

But some people have definitely claimed to have had a positive test, over 4-weeks after the vaccine, and more than you might think given those data. Of course all those people might just be on Mumsnet and wanting to spread that news...

Yes there do seem to be an awful lot of people on Mumsnet keen to spread any negative views they can find and debunk any positive factual reports. The trolling and orchestrated misinformation is a massive problem on here at the moment.

Some caveats on the Israeli data:
mobile.twitter.com/ZoeMcLaren/status/1363582050775744515

Are there any statisticians / data people who can explain why you are more likely to die than be seriously ill? I expected that the number of people dying would be smaller than the number of people getting seriously ill (because some seriously ill people will die but some won't). Is it just that there is not a significant difference between those numbers?

Deaths are often registered as dying with rather than of the virus. Often that’s the same thing, but if you imagine a hospital where everyone’s been vaccinated but there’s still lots of virus about, you’ll get some people who catch the virus, don’t get sick from it, but die from what they were already in hospital for.

Imagine a vaccine that prevents all serious illness that everyone has had - you’ll then get nobody seriously ill, but some people dying with (not of) Covid.

Ah thank you @HalfPastThree

I wouldn't have thought there would be that many people dying with but not of after vaccination, with such good numbers for preventing the infection.

I know the poster who mentioned AZ earlier got a bashing but I do understand her point. And let’s face it, we’re all so bloody desperate to be protected, we’re over-analysing everything.

I’m vaccinated. Was originally expecting to have AZ, then was told Pfizer. When I got to the clinic I asked the nurse which one I was being given and was told Pfizer. He then realised he’d run out of doses and grabbed one from the next station. When I was given my card after I’d had the jab it said AZ which wasn’t what he’d told me a couple of minutes earlier - I queried it, and the response was “it’s pot luck - we just give whatever we have but they all do the same thing anyway”.

I am INSANELY grateful to have received the first vaccine. Even if they’d told me it was AZ not Pfizer, I wouldn’t have hesitated. I realise how lucky I am. I also think it’s wonderful that Pfizer seems to offer such incredible protection.

At the same time I am desperately hoping that more research shows AZ might offer similar protection. The difference between 60% and 99% protection seems like a very big gap. When we’re all vaccinated, if my protection is only 60% I still have a one in three chance of getting ill. Compared to 99% protection from Pfizer.....

It’s absolutely not a competition, of course it’s not. But we’re all so desperate to get back to normality without exposing ourselves to risk, when your around CEV people, only 60% protection still seems quite risky.

@ExhaustedFlamingo Where have you got 60% from? If the dosage is over 12 weeks apart, it’s over 80%

"Well I for one am glad i chose the Pfizer now. "

How come you got to choose?

It was in The Lancet I believe, quoted an efficacy of 62%.

I believe, but I’m not absolutely certain, that it might be as high as 70% in some groups. Still a bit of a way off the 99% of Pfizer though. Even if you push the AZ to 80% (which I’ve not seen quoted), that’s still quite significantly below Pfizer. It feels almost like two-tier protection with many of the most vulnerable getting lower levels of protection.

Honestly, I don’t want to sound like an arse. I am truly and absolutely grateful to have had a vaccine of any kind. And it’s such early days for all of this. We’ll discover more about the efficacy of vaccines on different groups as they do more research.

I believe the 90% for AZ was only achieved when they gave a half dose followed by a full dose, which isn’t the regime we’re following. We’ve opted for two full doses which is where the efficacy of 62% was quoted.

There might be different stats floating around elsewhere and I’m completely open to being corrected. I’ve not been following it especially closely as it’s such an evolving subject, there’s something new every week. This article quotes some of the Lancet stats I’d seen mentioned www.nature.com/articles/d41586-020-03504-w

@ExhaustedFlamingo You don’t sound like an arse, you sound like a normal human being. I won’t go into my own feelings on it but everything I’ve read says 76% at 22 days to over 80% after second dose (3 month interval is a must) and no hospitalisation or death at all against our dominant strain.

@ExhaustedFlamingo the 67% is transmission

www.astrazeneca.com/media-centre/press-releases/2021/covid-19-vaccine-astrazeneca-confirms-protection-against-severe-disease-hospitalisation-and-death-in-the-primary-analysis-of-phase-iii-trials.html

@InkyWinky

Thanks for making those of us who had the AstraZeneca, feel as if we had the inferior vaccine!

Lol loads of us haven't had any vaccine yet. I am sure we aren't getting offended that a vaccine is doing well. I am sure if we got to 99.9% reductions in death and hospitulations MN and SAGE would still want us in Lockdown.

@Beemail1

"Well I for one am glad i chose the Pfizer now. "

How come you got to choose?

Some doctors are offering choice. When I phoned up to book mine I was offered an appointment at the surgery for the Oxford. I was a bit cheeky and asked if it was possible to have the Pfizer and she said yes as they were using that at the nearby hospital hub so she booked me in there 2 days later. She did the same for my husband and sister.

@SunshiningBetty Yeah, my GP has this on the FAQ on their website. “Do I have a choice which vaccine I get?” and surprisingly it said yes.

I am sure if we got to 99.9% reductions in death and hospitulations MN and SAGE would still want us in Lockdown.

Don't be daft. No one seriously wants lockdown forever. Well, if anyone does they can become a hermit.

@InkyWinky

Thanks for making those of us who had the AstraZeneca, feel as if we had the inferior vaccine!

Calm down

News this morning, stats showing spectacular impact of just the first dose of vaccine on serious illness with AZ outdoing Pfizer though both good (94%/85% respectively). The initial report is just Scotland so a relatively small number.

Covid vaccines - 'spectacular' impact on serious illness www.bbc.co.uk/news/health-56153600

Here’s some amazing vaccine news - and yes Oxford AstraZeneca is more effective at keeping people out of hospital than Pfizer!
news.sky.com/story/covid-19-vaccine-rollout-linked-to-85-and-94-drop-in-coronavirus-hospital-admissions-in-scotland-study-shows-12225532

Oops cross post!

This is a daft thread. All research not run by Pfizer or in association with Pfizer don't make it much better than AZ. People seem to forget this is a big pharmaceutical company with years of experience in marketing. AZ would probably act the same but their hands are tied because Oxford are very ethical.

If you want better protection from catching the virus Pfizer. If you want less chance of hospitalisation AZ. There in real terms is barely anything in it though.

@doireallyneedaname

Thank you for this. Could you please share the link?

I’d like to send to my antibacterial family who are so taxing misinformation, particularly as a elderly relative died last week from covid, but who only had one Pfizer dose about a week earlier. Family now saying that vaccine doesn’t work, period.

Genuinely amazed that they've allowed the BBC to run with the vaccines' success in Scotland today of all days

It's good news of course, but I'm just thinking of the pressure it'll bring to deliver an upbeat "roadmap"

AZ is excellent at preventing death & serious illness after one dose

Yes, let's not start bashing AZ.

Pfizer has it's own issues too (mainly allergies and new technology) - though it's great that it appears to be so effective

Are there any statisticians / data people who can explain why you are more likely to die than be seriously ill

Yes, I don't understand this either