Oxford

[wildbarnet]

Vaccine 70% I could cry is this good or bad ?

Better than the flu jab and we don't lock down the country for that.

This is about reducing pressure on the NHS, not about making sure no on ever gets I'll from Covid.

Importantly though, there were no severe cases of covid reported in the 30 who did catch it who had had the vaccine.

I think it's positive news OP

Depends whether you're a glass 70% full or glass 30% empty kind of person! But seriously, it is good, and apparently with a half dose followed by a full dose a few weeks later, it's 92% I think?

I read that the regulators will decide what dosage we get, as the group who got the half dose/full dose, the efficacy was 90%

do not lose hope

Thanks ladies I as with everyone else is just so tired of it all

I think it's good news, there were no severe cases of covid or hospitalisation in the people who received the vaccine and as @Iremembertheelderlykoreanlady said it's a better efficency than the flu jab.

It is good news op

It's not really new news so much as professionals (The Lancet) peer reviewing and confirming what we already know so far. Not the same as official approval so it can be rolled out; not there yet. And there's still more info to come down the line re the 1 and 1/2 doses.

I think the fact that none of the trial patients who received the Oxford vaccine got seriously ill with Covid is excellent news, even if some people got mild illness. And if by tweaking the dose they can improve the numbers getting full protection - well that’s even more hopeful!

Not a medical expert. It's OK as long as the vaccination rate is high. The vaccine is easier to transport, store and we are expected to get more of it. Therefore it may be more practical for vaccinating in residential settings to help to prevent death and serious cases. However, if the vaccination rate amongst adults is also low (less than 90%) I can't see it leading to a substantial decrease in cases for all. For a herd immunity effect (as we see with other vaccinations - measles, mumps, polio, dipheria) you need a high uptake of an effective vaccine. We still get UK outbreaks of measles and mumps as the mmr uptake is not high enough in some areas and that is a more effective vaccine (88% against mumps, higher against measles/rubella I believe).

Good news - 70% is good.

In an exam it would be a good solid result - and that is what we need

I read today that they are trialling a combination of vaccines, so a Pfizer followed by an Oxford/AZ, as they think this might give and even better efficacy by targeting different parts of the immune system.

Interesting theory, but will obviously take so time to come to fruition.

It'll do what we want! Nothing will get rid of it but if we can reduce the numbers and reduce the severity then job done for now.

Importantly though, there were no severe cases of covid reported in the 30 who did catch it who had had the vaccine.

Statistically less than 1 in 30 who get Covid get it severely anyway though tbf.

It's good. Maybe not brilliant, but good and welcome.

Did they trial it on people likely to get sever Covid? Older or obese people?

What was the criteria for the trial, was anyone vulnerable? It's ok saying nobody who contracted Covid was seriously ill, but if that is only a sample of healthy younger people then it may not translate to the same results in the population.

To me the main thing is how likely people are to die if they have been vaccinated and then get infected with covid. It seems the Oxford vaccine may reduce this a lot which is great news.

@notevenat20

To me the main thing is how likely people are to die if they have been vaccinated and then get infected with covid. It seems the Oxford vaccine may reduce this a lot which is great news.

Agree with this 100%

@picklemewalnuts

Did they trial it on people likely to get sever Covid? Older or obese people?

Phase 2 included 240 people over the age of 70 and was peer reviewed in the Lancet in November. It showed a strong immune response. Obviously we only have preliminary results of Phase 3, so I think will have to wait for the exact make up of those participates in Phase 3. But clearly Phase 2 is promising!

@Iremembertheelderlykoreanlady

Better than the flu jab and we don't lock down the country for that.

This is about reducing pressure on the NHS, not about making sure no on ever gets I'll from Covid.

Importantly though, there were no severe cases of covid reported in the 30 who did catch it who had had the vaccine.

I think it's positive news OP

Nothing about covid but your username is bloody fantastic @Iremembertheelderlykoreanlady

Only 46% efficacy when non-standard symptoms (like gastro) and asymptomatic cases are included.

Also only 2 severe cases in the control arm, so can we really be sure it protects from severe disease?

The age profile is surprisingly low overall and there is a preponderance of women (who tend to get less severe covid).

Interested to see what the experts make of it.

It’s good

And peer approved .

Cheaper and easier to store .

Great news

ForBlueSkies do you have a source for that please?

I personally much prefer two things about the Oxford trial.
a) they tested asymptomatic people. As far as I know in the Pfizer and Moderna trials they just assumed everyone asymptomatic didn't have it
b) Their placebo was a meningitis vaccine. This seems a much more convincing placebo to me. A saline placebo may well not fool a lot of people.

@notevenat20
Although the use of the Meningitis vaccine (and it's known side effects) as a control put many of participating in the trial. Other than for people truly at risk of Meningitis that vaccine shouldn't be allowed anywhere near humans (as the prevalence of side effects means the benefits of the vaccine aren't worth the risk of taking it in the vast majority of cases) .