Roll out the vaccine now?

[NewStart2020MyArse]

Testing is at a Phase III stage. There should be enough data to confirm efficacy and safety. I say fuck the normal red tape. This is a global catastrophe about to happen.

Take a look at how few people - just 543 - had the vaccine in the Phase I/II trials. They reported side effects which were judged to be mild but did leave with fever, chills and fatigue. One of the Phase I women was diagnosed with MS - judged to be unrelated. In Phase I just 10 participants were given a booster shot. Now in Phase III one woman developed inflammation of the spine 14 days after receiving a booster shot.

Although the U.K. have given the go-ahead to press on, the US authorities are more cautious. Based on all this, I would like more testing and more time before being vaccinated.

www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31604-4/fulltext

www.google.co.uk/amp/s/www.dailymail.co.uk/news/article-8744401/amp/Report-claims-Covid-19-jab-trial-paused-transverse-myelitis-left-woman-struggling-walk.html

not because I wanted the vaccine ahead of anybody else
but
I did fill in form to volunteer a few months back (not been approached but I felt that as a reasonable healthy younger (!) older person it might be useful data to see how long immunity last etc I was willing to take the risk)
but for general population they need to check/double check to make sure its safe, it works & how long immunity lasts in the blood

& Oh the dosage whether they will need supplement (like in flu) to activate immunity in older people or whether they will need two doses etc

I tried to volunteer when they were asking for clinically vulnerable volunteers but I don't live near enough to the relevant hospital.

safety I'm not worried about at all but sheesh, govt spending all that public money on a vaccine (getting millions of doses) that may not even give a person immunity for as long as 2 months -- that is a huge problem and bad way to spend money.

I work in clinical trials.

And yet you don't understand the reasoning for clinical trials. I have my doubts you do.

An untested vaccine could be worse than covid.

The 1955 polio vaccine in America went terribly.

And whilst not a vaccine thalidomide didn't go well.

That's why we need to be cautious.

And I volunteered for testing early on but didn't hear anything, before you think I'm anti Vax, I'm against rushing it.

See if you can get Sputnik privately.

I'll take my chances with virus until properly tested vaccine is available.

You realise the damage that could be done with rolling out an ineffective or worse, a dangerous vaccine? The anti-vax movement is dangerous enough already.

You are assuming huge amounts of the vaccine can be manufactured quickly and safely.

This is a pretty good article
www.cnn.com/2020/09/01/health/eua-coronavirus-vaccine-history/index.html

It’s not just the safety/efficacy of the vaccine that needs to be signed off. There’s loads of logistical issues like transport and storage (prob needs to be refrigerated) not to mention the possibility of having to do 2 jabs (how to do follow ups?) plus identifying those in priority groups (how to decide?). This isnt going to happen quickly!

Jesus wept. People really don't understand how testing a vaccine works and the answer is a hard fucking NO. They need to clear it properly and have solid safety data. You wouldn't be able to find a doctor in the fucking land to sign off on that one unless you got say a Russian one....

No.
Hancock said the first people in line would be healthcare workers, care home workers, and over 70s so there's a while until I get the chance anyway. (He might have added teachers to this group or the next group but I can't remember)

You are assuming huge amounts of the vaccine can be manufactured quickly and safely.

That’s not an issue, it’s already been done.

If it gets go ahead, they will be able to move pretty quickly (though not quite as quickly as everyone would like I’m sure).

But this is the bit that can’t be rushed.

Hmm, think I'll hold out for a number years until they have actual data on the long term effects and not just what someone has experienced a couple of months post jab. Everyone is so scared of the long term health implications Covid may cause in some people but don't seem to care a jot that vaccines can cause the same thing.

I don't think we need to rush it through. The trials will conclude fairly soon anyway I would have thought, especially if cases are rising, more chance of people in the trial group contracting the virus.

They are already manufacturing at scale so once the trial is concluded and the vaccine is licensed they can start the roll out. I don't think there is an argument for skipping these final steps as things stand.

@StoorieHoose good luck waiting for the next phase because there isn't one. It goes pre clinical, phase 1, phase 2 and phase 3. This is in phase 3. There is no more phases after that, it will just be released.

Then I'll wait til it's been released properly after due process... Even then I wouldn't rush to get it - I'm sure there is people like NHS workers than would need it more than me

I work in clinical trials.

I don't believe you, but if you do what other things would you skip on for expediency?

There are Nobel prizes and untold riches waiting for the team that cracks this virus, they'll be the next Pasteur! Dont you think they'd be the ones to green light the next stage if it was appropriate?

Oh no, OP, please, after you. 🤔

@TSSDNCOP

I work in clinical trials.

I don't believe you, but if you do what other things would you skip on for expediency?

There are Nobel prizes and untold riches waiting for the team that cracks this virus, they'll be the next Pasteur! Dont you think they'd be the ones to green light the next stage if it was appropriate?

Believe what you like It's the MHRA, FDA, EMC, and other health regulator bodies that can approve a quicker process not the clinical team or pharmaceutical companies.

@WhereIsTheRealMe I meant the part about working in clinical trials. But then I think you knew that and just fancied being a bit difficult.

You can sign up for the trial, one of my friends at a London teaching hospital said over half her colleagues have (and her). Personally I'm not bothering because I've had covid and it was very mild in me

And when the vaccine is rolled out I'm in the lowest priority group (younger, white, female, no underlying health issues)