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Conception

When's the best time to get pregnant? Use our interactive ovulation calculator to work out when you're most fertile and most likely to conceive.

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Original poster

RESPONSE trial thread

984 replies

Marchgirl · 04/05/2015 19:50

For anyone who had joined or is thinking of joining the RESPONSE medical trial for recurrent miscarriage

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17
Kazz2112 · 01/06/2015 13:17

They've come back clear. Feel.gutted..was hoping for a simple answer

Original poster
Marchgirl · 01/06/2015 13:27

Sorry you're disappointed about the results kaz. It's a horrible feeling to want there to be something wrong even though you don't want there to be something wrong iyswim. Not having an answer is the worst, although even if you had a clotting issue it still could have been difficult. I don't think either result would have been simple.

Really hope the positive prospect of being on the trial helps you to feel ok about it when you've got your head round it. At least it means you can carry on with response. And Just look at all the positives on this thread! You will get your baby. Keep the faith x

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Kazz2112 · 01/06/2015 13:54

I know. It definitely helps being on here. Let's hope that one of my test results this week is a bfp

Indiedog · 01/06/2015 15:52

Girlie, I will ask my friend about who she used for acupuncture. I can't remember if she used it for giving up smoking or her fertility as she had IVF. Just can't place the time she was having it! Bear with me, I will text her later if that's ok. Xx

clairemorgan81 · 01/06/2015 16:44

Hi ladies

here was me thinking you had all gone quiet as I've had no email notifications and I've just checked in and you's have been non stop!!

choccy - lovely little bump eek half way there that's fabulous.
kazz I hate preg testing so early it totally does my head in and I hate the disappointment, good luck its so early though. hope your okay about results. I felt similar when mine were all fine too.

pleased you got your early Smile. March , maybe the not planned approach will work I really hope so for you.

I got my pos opk last night (day 14) Smile

hope everyone is okay...... I use a little plastic shot type glass which belongs to ds teaset!!x

clairemorgan81 · 01/06/2015 16:49

choccy forgot to add you are sooo slim!! very envious!!
I started acupuncture on Fri, hoping it helps as quite pricey x

girliesaints · 01/06/2015 16:58

Thanks Indie, no rush. It's on my list to sort out at some point along with all the jobs we've put off doing whilst we were in limbo x

Claire's, I have high hopes for you this month x

girliesaints · 01/06/2015 16:58

Thanks Indie, no rush. It's on my list to sort out at some point along with all the jobs we've put off doing whilst we were in limbo x

Claire's, I have high hopes for you this month x

clairemorgan81 · 01/06/2015 17:03

how you feeling girlie? I hope your recovering okay?
ha I'm beginning to lose hope with ttc. it just doesn't seem to be going to happen for us anytime soon xx

girliesaints · 01/06/2015 17:32

Feeling ok, though I've got period like pain but less blood loss than I've had previously (sorry if tmi)

I've decided to have this week off as sick and then I'll go back next week so hopefully it will have settled down my then. Mentally I'm fine, which is freaking me a bit as I keep expecting to have a breakdown. Perhaps the three weeks of limbo helped prepared me.

Claire, i reckon when you do get a bfp it's going to be super sticky! The response nurses seem to agree other my theory than I'm super fertile as I seem to fall the first month of trying, which leads me to think it's accepting any old rubbish egg!

Original poster
Marchgirl · 01/06/2015 17:33

I have high hopes for you too claire, and it looks like we'll be almost identical times testing this month. Hoping for two bfps!
How did you like the acupuncture? I go every week but only because it's cheap. Wouldn't be able to afford that often at full price.

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clairemorgan81 · 01/06/2015 17:48

girlie I hope your resting up. I felt like that after my last loss the time in limbo kind of prepared me, doesnt make it easier just more accepting as I knew deep down. its so bloody shit.

March yes were close again this month - did you get Smile on Sat?
acupuncture was good, I felt a bit strange as I can't see how it will help but I'm hoping for some results. weekly sessions at moment hoping to go to every other week soon for cost x

Kazz2112 · 01/06/2015 17:50

Glad you're recovering Girlie. I think taking a week off is a good idea. Just to give your body a rest.

How long have you been ttc for Claire? Have you caught quite quickly before? Here's hoping that this month is a good month for both you and March! And that I can't join you with a bfp.

Original poster
Marchgirl · 01/06/2015 18:13

I think the hyperfertility theory does fit for you girlie, I hope Coventry brings you some answers x

I just got my smiley this morning claire, but didn't test yesterday so suspect I would have been smiley yesterday pm as I normally get PM smiley before AM one. I also got a tiny silk thread of blood yesterday afternoon so wondering if I might even have ov then (in which case dtd timing was even worse). Anyway, I'll be starting the progesterone next Monday and probably testing from next wed or thurs. What's your testing plan?

kaz, I'm hoping you'll have bfp at least a week before us Grin

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Kazz2112 · 01/06/2015 18:35

I'm hoping by thursday. After that ill start to prepare for AF which I expect between Friday and Sunday.

What do you all know about hcg levels?

I read somewhere natural level is between 0.5ul and 5ul (not sure if that's the correct unit!) And the doubles every 72 hours post conception.

So some people can double to 10 then 20 within 6 days (Choccy??) So can detect very early whilst others (ie. Me I think!) Don't reach a detectable value until AFTER AF is due. (Increases 1,2,4,8,16,32) I reckon I fall into the low category as I did my very first test for first pg the night before AF was due. But didn't get a positive till 4 days late (although I didn't test in between ) and even then it was very faint.

Would this make sense for anyone else?

clairemorgan81 · 01/06/2015 18:52

kazz we started trying last March had 3 losses between May and jan and have been ttc since Feb. I caught quickly last year but this year its taking longer. I dont know if it's because im a lot more stressed now than I was plus being on trial means I'm thinking of it so Much more or maybe it's just one of those things. my biggest fear is it taking ages then m/c again.
I hope you get your bfp this month. have you fallen easily in past?
same as me then March I tested about this time last night and had Smile and it was still there this morning. would you not have a negative opk if you had ov yesterday (hence thread of blood?) I'm not 100% sure if levels decrease straight away after you have ov?

I'm not clued up on hcg levels but makes sense to me kazz x

clairemorgan81 · 01/06/2015 18:54

Oh and March I 'll prob start testing next Mon or tues although after how bad it made me feel last 2 months I may try and hold off a bit?x

Kazz2112 · 01/06/2015 18:59

You sound exactly the same as me Claire. Started trying February last year. 3mcs May, October and January. Waited until April to startTTC. This is our 2nd cycle trying to conceive

Original poster
Marchgirl · 01/06/2015 19:27

I normally get 3 days positive opk with the middle one being ov day claire. Also for that reason it would seem odd for me to have ov'd yesterday as opk was negative on Saturday. But today's cm seems post ov type (but have crampy ovaries - so confused!). Hoping to know more with tomorrow's temp.

I would agree that some people generate hcg quicker than others kaz. I only know this from speaking to (lots of) pg people on here, not from any science! Noticed a lot of people who talk of regularly getting bfp around 8 or 9 dpo, whereas i have never got one before 11.
I think Hcg is driven by progesterone so from the science point of view, it would make sense that some people build up hcg quicker than others if their progesterone levels vary. Having said all that, as I've discovered is true of almost everything related to pregnancy, there seems to be a huge range that still falls under the heading of 'normal', both in relation to hcg and progesterone. Fingers crossed your line will show up soon x

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Original poster
Marchgirl · 01/06/2015 19:29

I think you'd be wise to hold off a bit if it was stressing you out claire. I'm just a poas addict!

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clairemorgan81 · 01/06/2015 19:42

so you get a positive opk after ovulation March? that's interesting as I presumed it would go negative first. I am thinking of starting temping next month. I have no idea what I'm doing really......when do I start/what kind of thermometer and where do you take temp? Sorry about quizzing you x

Original poster
Marchgirl · 01/06/2015 20:37

That's fine! Yes, my LH surge seems to take a while to settle after ov.

I temp vaginally although I used to do orally but i find this thermometer is a bit big to stay under the tongue easily. It's also supposed to be a bit more accurate vaginally. At the moment i use a glass thermometer because i don't want to wake dh with one that beeps (he works shifts), but it's a basal body temperature one. I think it would be much easier to use a digital as mine takes 4 minutes to cook,which i just count in my head, but sometimes i lose count because I'm dropping off!
I found it gave me back a feeling of knowing what was going on with my body, but it can induce a bit if the crazies if you're obsessive at all (like me!)

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clairemorgan81 · 01/06/2015 20:41

thanks for info March. i may attempt next month so may quiz you again nearer time x

Kazz2112 · 01/06/2015 20:49

I just read that and thought... ooohhh... I may try that if unsuccessful this cycle... will just get one from work (I'm A science teacher!) Then I thought of all the grubby hands that have been on them...

Kazz2112 · 02/06/2015 06:13

Another bfn this morning. Got strange cramps this morning. :s If I got a smiley a week past Sunday what day post ov am I approximately on? 9?

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