RESPONSE trial thread

[Marchgirl]

For anyone who had joined or is thinking of joining the RESPONSE medical trial for recurrent miscarriage

Can't beat a first response. I have some on Standby. Hopefully for confirmation in the not too distant future. About to start ovulation testing Wednesday. I'm actually nervous I'm going to do it wrong!

oooppps. Posted twice

Philippa !!!! Massive congrats!!!! After the fuck up with your af, that's massive massive news!!!!!

Claire, how's your friend? :(

Just on train back from London, stayed an extra night as ds not back til this aft anyway and the weather was gorgeous! Was bloody fabulous long weekend!!!!
Cleo from girl band Cleopatra was one of the leads in Thriller (best show we've ever seen!), and we met her afterwards and she even sang I'll be There to Pip!!! Dh filmed it :) It was totally emotional and she was so lovely. Faultless voice on her!
Best weekend for a long time, spent a fortune (literally) but just thought screw it!
Going to be a quick week too. Out tonight for mil birthday, tomorrow having a relaxing day, weds meeting some mumsnet girls in Birmingham that we've all been chatty for for 18+ months (met some of them in London a few weeks back, was fab), Thursday last shopping bits for holiday, Friday hair appt and mw appt, Saturday hols!!
I need to get some flight socks, just remembered!

Thanks choccy! We're currently at the hospital waiting on the medication, had ALL those bloods taken and then when we go back have to do the injecting and waiting! Still feeling pretty surreal...

Glad you enjoyed you're time away, it's always nice to just get away and chill out. How cute she sang to Pip! Xx

Well done Philippa, it's becomes a little more real as your little yellow tub fills up day by day!!!

I am still managing to keep things from my work mates! I hide my heaving well!!
I am 11 weeks today, and I can not believe it still. My last injection will be next Monday, before we leave for Spain!
At least I will have a week of distraction to keep me from worrying about not having injections. That's what I am going to find scary, not relying mentally on an injection keeping this little bean, and that's it will be down to me!!!!! I don't want to fail again!!

Anyho, must crack on, kitchen to tidy, dinner to get ready, blah blah blah,

Hope everyone is ok. Xx

sounds like you had a fab weekend choccy......and such a lovely week ahead for you.
I've not seen my friend just a few txts since Fri, she's completely numb which is understandable. I'm not sure how much contact she 'll want at moment with at that will be going on but I've let her know I'm here whenever/if she wants to talk or some company. I just cannot imagine her pain so I'm not pretending to

had my 3 month bloods done again today, got more shitty pref tests arghh they are horrid!!

Hope everyone is okay?

March any sign of af yet?x

preg

Well I've had my first injection! My oh did really well with the injecting :) the areas a little sore but guessing that's normal! Got our next appt on Thursday when by their logic I'll be 4 weeks. Seems so surreal!!!
X

Well done on the first injection philippa

Still no sign of af claire. I'm normally v regular and stopped progesterone 3 days ago so expected it by now but just spotting. Stupidly ended up testing again this morning, which was totally ridiculous. Obv bfn again and just made me feel shit again. Stupid.
Has yours arrived?

Glad to hear Philippa you've had you're randomisation appointment and had first injection. I soon got used to my daily injection, although I have cracking bruise on tummy at moment- oops!

choccy-well jel about your weekend

I've turned into a eating/ icky woman this weekend. If not eating, feel sick. Wish I could assume it was a good sign but been here before with previous MCs. Weight is starting to pile on rapidly- ggrh!

When is your appointment Girlie? Still finger crossing and positive thinking for you!

How exciting Philippa. Glad to hear you're started on your injections.

I've been back at the hospital today for a uterus scan and more bloods due to some of the trial nloods showing up low levels of possible sticky blood disorder. Did anyone else have to have bloods redone? Got to wait two weeks now to find out the results and if I van participate on the trial or if I will just need Heparin for my next pregnancy.

The scan showed I have a bicornuate (irregular) shaped uterus too so not sure how that may affect the trial!

Oh... picked up my pregnancy tests too. They're clearblue ones :)

well done philippa

March yes af arrived this afternoon (hoping so anyway after my 5 days of browny crap wish that would f off....sorry yours hasn't arrived yet and I know what you mean about getting another bfn I had test done this morning at hospital (before af had arrived) and bfn which of course I knew but I still felt rubbish! hurry up af. its funny isn't it you pray af won't come then pray it will so you can start again.
I hope it shows tomorrow for you.

girlie I hope these are positive signs for you. when's your scan -wed?x

sorry your having the uncertainty of whether you can join trial or not kazz. I had bloods redone but it was for something unrelated to miscarriage. so is that lupus? sticky blood? if it's still low it is treatable so please try not to worry too much.

lucky you getting cb ones!x

I'm not worried about the bloods results. The next time I fall pregnant ill either be on the trial and have the support of that or I'll be being treated for a known condition so either way my chances are increased.

I'm just a little concerned about the uterus abnormality. But the sonographeromone said it's more linked to inability to conceive and seeing as I've successfully conceived three times I should be ok!

I think it was the lupus one. my first one from the recurrent miscarriage clinic hadn't come back when I signed up for the trial and has suggested be apparently come back inconclusive. The trial test showed a low result. Just going to focus on ttc this cycle and by the time i hopefully get a bfp I'll know which route we have to take!

Has no one else been given clear blue pregnancy tests?

Thanks everyone! Kaz I had both the crappy tests and clearblue ones..
I'm refraining from testing anymore - past pregnancies I've tested daily to check on the lines and it just stresses me out. I'm being as positive as I can now - like I keep saying, I just don't think it seems real! It's like we've waited for the day to start injections and now I've had one - it still hasn't clicked in my brain! Xx

Sorry kazza, you've had to have some bloods redone. At least you're in safe hands x

Yep scan wed and should be 8 weeks

Not long now till Wednesday. Hope it brings you some good news and reassurance. Big hugs and hand holding.x

Kazz, I have a funny shape uterus, can not remember the name. Mine tilts back too. But this hasn't affected conceiving, and as I have a DD who's 6, holding a pregnancy either. So hopefully they can explain a little more, and you will feel reassured.

Philippa, on my record sheet, I write the time, and I put a L or R left or right for what side I injected, as I was always forgetting!!!!
I have bruised twice out of the whole lot, both times cos I knicked a capillary. It's nothing, tiny bit of blood, bit sore, then that's it.
I hold my syringe in my hand whilst I take it upstairs, just warms it a little. I found if it's really chilly it stings a bit more!!

Girlie, so pleased your scan is soon. Keeping everything crossed. Xxx

:) that's reassuring. Thank you.x

Girlie what time is your scan tomorrow I've got mine tomorrow at 8am. All my symptoms have gone and I've got really bad back ache which is exactly the same as my first mmc we seen a heart beat but it measured 2 weeks too small.
I've stupidly googled how big it measured and it was just short of 2 weeks out :( so I think mines going the same way as then.
I have everything crossed for you tomorrow xx

Oh Louise stay away from google!! It does nothing but worry and stress you. Fingers are crossed for tmrw, I really hope the results are good news. Go buy some nice comfort food and try to relax, I'm only 3+5 and I'm trying to keep those negative thoughts at bay - it's not easy! Xx

Gpod luck to both of you for tomorrow. Lots Of positive thoughts heading your way

Girls I really need some help :( :(
I can't stop thinking the worst and it's reducing me to tears. I just don't know where my positivity has gone and I've got full on cramp so just expecting the worst :( xx