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Cancer

Find advice & support if you or someone you know has been diagnosed with cancer

Colon cancer CAPOX

30 replies

littlebilliie · 05/09/2025 19:36

Has anyone had Oxaliplatin and capecitabine?

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SeptemberNCing · 05/09/2025 23:38

Those are the drugs I had, although it was around 17 years ago.

Remaker · 05/09/2025 23:39

Yes that’s the chemo I had in 2023. What would you like to know?

MissFritton65 · 07/09/2025 10:27

My husband is on these drugs for oesophageal cancer.

littlebilliie · 07/09/2025 20:22

Hello, I’m quite worried. I’m worried about neuropathy. I’ve been offered three months on CAPOX or 6 on capecitabine. Both routes are looking incredibly hard

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WeaselsRising · 07/09/2025 20:33

I had Oxyplatin but not the other you mention. I did have neuropathy but it got better once the treatment had finished. That was 14 years ago.

littlebilliie · 07/09/2025 20:56

MissFritton65 · 07/09/2025 10:27

My husband is on these drugs for oesophageal cancer.

Hi is he coping with the treatment

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MissFritton65 · 07/09/2025 21:22

@littlebilliie he's tired but still working. He is sometimes sick but as he's got oesophageal cancer probably not unexpected. He's on 6 sessions of capox with trastuzumab and pembrolizumab.

MissFritton65 · 07/09/2025 21:24

He's on 3 week cycle with no breaks.

comfyshoes2022 · 07/09/2025 21:28

Do icing for neuropathy.

SeptemberNCing · 07/09/2025 21:31

I has neuropathy and it lasted for maybe a year, but I would still have it in cold weather for maybe 5 years or so.

I also then had Raynaud’s for several years after, not sure if it was connected but that eventually stopped too.

I was on really high doses of the drugs though.

littlebilliie · 07/09/2025 21:59

I’ve been reading that cold is the worst and very triggering. How does it work in the cold? Did everyone wear a scarf over their mouth?

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SeptemberNCing · 07/09/2025 22:07

littlebilliie · 07/09/2025 21:59

I’ve been reading that cold is the worst and very triggering. How does it work in the cold? Did everyone wear a scarf over their mouth?

I never had it on my mouth, only my hands and feet.

I would use hand warmers for my hands and wear thick boots with two pairs of socks to keep my feet warm.

littlebilliie · 07/09/2025 22:17

@SeptemberNCing thank you that’s a good thought

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Tootingbec · 07/09/2025 22:20

I’m sorry you are going through this - it must be tough and scary but I am glad you are getting the treatment you need.

My husband had neuropathy while on the 4 month chemo cycle for colon cancer - coincided with winter so not great.

But we just made sure he had tepid water, good socks and gloves and a scarf over his nose and mouth but only when frosty cold. But we are south so winter temps not too harsh so it was ok most of the time.

He is 4 years post treatment and very very occasionally he feels it in his extremities on a cold day - but it’s very mild now, more like when you get sensitive teeth sometimes in the cold.

Remaker · 08/09/2025 00:11

I had CAPOX for 3 months in 2023. I had neuropathy in my hands and feet afterwards. Acupuncture was very helpful, my hands are completely fine now. I do still have it in my feet however it is a bit of numbness in patches, not painful at all and doesn’t impact my mobility. My feet feel the cold so I always wear socks, even in the Australian summer.

During treatment I experienced some pain on the soles of my feet so I’d have to stay off them for a day or two. I told my oncologist and she adjusted the dose for the next infusion. I was very sensitive to cold, breathing in cold air made me wheeze for a couple of days after infusions. I wore gloves and warm socks. This was the Australian winter so no ice or snow and temps around 10-12 degrees on the coldest days.

Capecitabine caused me to lose skin off my feet and a tiny bit off my hands. It was like the best pedicure ever my feet were so soft! It made my skin look amazing as it basically gets rid of all your age spots and anything sun damaged or inflamed. My chronic heartburn vanished. So there is a positive side to it!

When they give you information about side effects they have to tell you all of the possibilities but most people will only get some. I never had mouth ulcers, didn’t really have nausea. I lost weight due to no appetite but I didn’t feel sick. I never had a single virus or illness while on chemo and didn’t get so much as a cold for over two years afterwards.

You are doing the right thing asking for information about the specific treatment that you will be having. People will try to tell you horror stories about ‘chemo’ but the vast majority are not relevant as it’s different drugs. It’s a very daunting time before you start treatment, I found it better once I actually started and knew what I was dealing with. Feel free to ask anything else here or PM me.

littlebilliie · 08/09/2025 07:58

Thank you so much for your responses. I am quite scared of this treatment as the side effects are described so drastically.

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littlebilliie · 08/09/2025 08:00

MissFritton65 · 07/09/2025 21:24

He's on 3 week cycle with no breaks.

This is what I am recommended

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SeptemberNCing · 08/09/2025 08:16

I was also on the 3 week cycles.

Personally, I felt rough the first week, second week is when I started to feel more like me and third week I was strongest. I would book myself a treat for that third week so that I had something to look forward to. I have given that advice to others who said it massively helped them too, so maybe it’s something to think about.

saraclara · 08/09/2025 08:22

My husband had that protocol 16 years ago. Yes, he did have neuropathy, but those drugs spare you a lot of the more well known chemo side effects. So no nausea, vomiting etc. My DH's oncologist described it as one of the 'kinder' chemos. Like a pp, we planned our activities around the times when he was less tired, and were able to live pretty normally throughout the course.

littlebilliie · 08/09/2025 10:34

saraclara · 08/09/2025 08:22

My husband had that protocol 16 years ago. Yes, he did have neuropathy, but those drugs spare you a lot of the more well known chemo side effects. So no nausea, vomiting etc. My DH's oncologist described it as one of the 'kinder' chemos. Like a pp, we planned our activities around the times when he was less tired, and were able to live pretty normally throughout the course.

Thank you that sounds reassuring

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littlebilliie · 08/09/2025 11:37

Remaker · 08/09/2025 00:11

I had CAPOX for 3 months in 2023. I had neuropathy in my hands and feet afterwards. Acupuncture was very helpful, my hands are completely fine now. I do still have it in my feet however it is a bit of numbness in patches, not painful at all and doesn’t impact my mobility. My feet feel the cold so I always wear socks, even in the Australian summer.

During treatment I experienced some pain on the soles of my feet so I’d have to stay off them for a day or two. I told my oncologist and she adjusted the dose for the next infusion. I was very sensitive to cold, breathing in cold air made me wheeze for a couple of days after infusions. I wore gloves and warm socks. This was the Australian winter so no ice or snow and temps around 10-12 degrees on the coldest days.

Capecitabine caused me to lose skin off my feet and a tiny bit off my hands. It was like the best pedicure ever my feet were so soft! It made my skin look amazing as it basically gets rid of all your age spots and anything sun damaged or inflamed. My chronic heartburn vanished. So there is a positive side to it!

When they give you information about side effects they have to tell you all of the possibilities but most people will only get some. I never had mouth ulcers, didn’t really have nausea. I lost weight due to no appetite but I didn’t feel sick. I never had a single virus or illness while on chemo and didn’t get so much as a cold for over two years afterwards.

You are doing the right thing asking for information about the specific treatment that you will be having. People will try to tell you horror stories about ‘chemo’ but the vast majority are not relevant as it’s different drugs. It’s a very daunting time before you start treatment, I found it better once I actually started and knew what I was dealing with. Feel free to ask anything else here or PM me.

Was acupuncture part of your treatment

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Remaker · 08/09/2025 21:19

@littlebilliie I was treated at a specialist cancer hospital in Sydney and they offer complementary therapies to help with symptoms. I started acupuncture towards the end of my treatment and continued with it for about a year after.

littlebilliie · 25/09/2025 22:37

Well this is mean

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Sbmpp · 15/01/2026 02:22

@littlebilliie Iwas on those drugs in 2024. The parentheses were something but they went away. I’m now on taxol and a TT. I have parathesias but am tolerating them well. Just hoping it works for as long as possible. Blessings ♥️.

littlebilliie · 31/01/2026 21:52

Hi all thanks for all
your messages I finished treatment in December nd I’m still feeling neuropathy in my feet and it’s a bit depressing. Any cheerful stories are welcome

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