Thumbwitch; I know someone who had the most awful (lie in dark room, no noise, crying at strangers) migraines and tried everything (from most expensive to most wacky) in desperation. One of her doctors gave her a drug that she could inject into her own thigh. I remember her telling us about this wonder drug (I don't know what the drug was, only that it had to be injected into the thigh) and how fabulous it was. Problem was, she ended up being addicted to this prescription drug and had to then spend a week in the Priory coming off it.
She is back on the migraines. I think it may have been something related to opium, because her son used to tell people his mother was a heroin addict.