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Share your dilemmas and get honest opinions from other Mumsnetters.

To wonder if there will be any fall out from skinny jabs?

659 replies

TheLemonGuide · 20/04/2026 16:40

Everyone I know is now suddenly very slim. Okay, im exaggerating slightly, but genuinely, most of my friends who were previously overweight are all now slim thanks to skinny jabs. I am delighted for them! It seems unbelievable to think that a jab can cure this obesity crisis, but I am so pleased my friends and a couple of family members are able to live a healthier life thanks to this.

My only slight concern is, is this something that is going to be too good to be true? Do you think there will be any long term repercussions, or are we right to just celebrate this medication as a cure for something that so many have been battling for so long?

OP posts:
InfoSecInTheCity · Today 09:01

icecreamflowers · Today 01:48

Be that as it may, gallstones and gallbladder inflammation are known adverse side-effects of WLI, listed by the manufacturers (along with gastroparesis, ileus, pancreatitis, and so on).

You can get pancreatitis through drinking too much alcohol, or through an injury - but the pancreatitis on the warning list of adverse effects of WLI is specific for WLI.

Because gallstones and gallbladder are known effects from weight loss, so anything that causes weight loss will have that potential side effect. If the possibility of gallstones is what stops you from using WLIs then it would also stop you from losing weight and make you cautious of advising others to lose weight via ANY means. So in effect what you would be saying is that people should stay obese in order to avoid an effect of losing weight. Irony being that obesity is also a cause of gallstones and gallbladder inflammation so it’s a rock and a hard place situation.

icecreamflowers · Today 09:14

Pikachu150 · Today 08:54

I was poster 2. You can get it off the internet but still is prescribed by a suitability qualified person and they ask a lot of questions. The person with bulimia is obviously lying about her history.

Well, of course she has lied - that is if she went about it in any legitimate way. And now 7/8ths of her formerly abundant hair has fallen out.

A "suitably qualified person"? You do realise that these drugs are being used worldwide? You can buy them off any old shonky person on the internet.

icecreamflowers · Today 09:29

InfoSecInTheCity · Today 09:01

Because gallstones and gallbladder are known effects from weight loss, so anything that causes weight loss will have that potential side effect. If the possibility of gallstones is what stops you from using WLIs then it would also stop you from losing weight and make you cautious of advising others to lose weight via ANY means. So in effect what you would be saying is that people should stay obese in order to avoid an effect of losing weight. Irony being that obesity is also a cause of gallstones and gallbladder inflammation so it’s a rock and a hard place situation.

I don't need to use WLI. I was merely pointing out that these are listed adverse effects. Lots of people get stretchmarks when they lose weight, but that is not a listed adverse effect. There is a reason the pharmaceutical companies list these particular adverse effects, and not any number of other possible repercussions of losing weight.

DoughnutDreamer · Today 09:33

Pikachu150 · Yesterday 20:52

We have about 20 years of data on the drugs. We also have data on the long term effects of obesity. I think the benefits of these drugs are very likely to outweigh the risks long term.

I think for obese people WLI are amazing and I know a small number of previously obese people whose lives have been improved no end by using WLI. But what about the long term effects on people who aren’t obese and who only have a small amount of weight to lose? Will the benefits outweigh the negatives for them?

Witchonenowbob · Today 09:42

DoughnutDreamer · Today 09:33

I think for obese people WLI are amazing and I know a small number of previously obese people whose lives have been improved no end by using WLI. But what about the long term effects on people who aren’t obese and who only have a small amount of weight to lose? Will the benefits outweigh the negatives for them?

But how can we legislate for any misuse of drugs? People misuse drugs all the time, painkillers especially! We can’t say no painkillers as some abuse it?

pdjafcwtaoa65 · Today 09:53

DoughnutDreamer · Today 09:33

I think for obese people WLI are amazing and I know a small number of previously obese people whose lives have been improved no end by using WLI. But what about the long term effects on people who aren’t obese and who only have a small amount of weight to lose? Will the benefits outweigh the negatives for them?

What’s interesting is that a lot of the risks that come with WLI are lower for people with lower BMI, if you have less to lose you’re less likely to go onto higher doses, and less likely to experience rapid weightloss which is the driving cause behind most of the more severe repercussions of WLI. I suspect that’s why prescribers such as Voy have started prescribing at a BMI of 25 off label.

DoughnutDreamer · Today 10:01

Witchonenowbob · Today 09:42

But how can we legislate for any misuse of drugs? People misuse drugs all the time, painkillers especially! We can’t say no painkillers as some abuse it?

I don’t know how. And I don’t know what the answer to it is. I just know that I know more people misusing them than I know who are using them for genuine reasons.

fiversinmycar · Today 10:07

If a new drug comes out that helps people with cancer or Alzheimer’s or any other illness, you absolutely NEVER hear anyone say ‘Oohh…I wonder what the long term side effects will be’. No, it’s just celebrated as a fabulous advance in science.

Smokers are allowed nicotine patches, people with addiction/alcohol issues are allowed drugs…but us fatties? Nope, we must do it the ‘hard way’. WLIs are simply a tool to help people achieve something they’ve likely spent decades trying to conquer.

Witchonenowbob · Today 10:40

fiversinmycar · Today 10:07

If a new drug comes out that helps people with cancer or Alzheimer’s or any other illness, you absolutely NEVER hear anyone say ‘Oohh…I wonder what the long term side effects will be’. No, it’s just celebrated as a fabulous advance in science.

Smokers are allowed nicotine patches, people with addiction/alcohol issues are allowed drugs…but us fatties? Nope, we must do it the ‘hard way’. WLIs are simply a tool to help people achieve something they’ve likely spent decades trying to conquer.

Absolutely!!

It’s so bizarre!

SwingTheMonkey · Today 11:05

fiversinmycar · Today 10:07

If a new drug comes out that helps people with cancer or Alzheimer’s or any other illness, you absolutely NEVER hear anyone say ‘Oohh…I wonder what the long term side effects will be’. No, it’s just celebrated as a fabulous advance in science.

Smokers are allowed nicotine patches, people with addiction/alcohol issues are allowed drugs…but us fatties? Nope, we must do it the ‘hard way’. WLIs are simply a tool to help people achieve something they’ve likely spent decades trying to conquer.

I think when it comes down to it, it really isn’t genuine concern. Or, as you say, any new to the market drug that has wondrous benefits to the user would see the same ‘concern’ about potential future side effects.
I think many, many people, whether they admit it or not, would like to see some repercussions in the future as a punishment for fat people losing weight in a way they see as cheating. Because apparently weight loss must be hard and unpleasant as a punishment for the moral failure in becoming overweight in the first place…

susiedaisy1912 · Today 11:07

You can’t fix stupidity, if some people want to abuse the use of medication despite all the warnings and education available then there’s not a lot you can do other than let them get on with it and suffer the consequences. You can’t ban everything just because a small minority of people are irresponsible.

icecreamflowers · Today 11:07

If a new drug came on the market for people with cancer or Alzheimers' nobody who didn't have cancer or Alzheimers' would be wanting to use it.

Frequency · Today 11:14

If an Alzheimer's drug came out that was heavily marketed as being the only way you could avoid alzheimers, was being sold for profit with little to no medical oversight, and being used by people who do not need it, I can guarantee people would have something to say about the potential fallout and side effects.

You cannot compare WLI to other prescription medications because no other prescription medications are marketed and sold this way.

susiedaisy1912 · Today 11:14

SwingTheMonkey · Today 11:05

I think when it comes down to it, it really isn’t genuine concern. Or, as you say, any new to the market drug that has wondrous benefits to the user would see the same ‘concern’ about potential future side effects.
I think many, many people, whether they admit it or not, would like to see some repercussions in the future as a punishment for fat people losing weight in a way they see as cheating. Because apparently weight loss must be hard and unpleasant as a punishment for the moral failure in becoming overweight in the first place…

Exactly, you’ve hit the nail on the head. Deep down people are pissed off that overweight people have a tool to help them loose weight without suffering from constant hunger and unhappiness. It’s a deep rooted bias that most of us have without even knowing why that links obesity to greediness and slovenliness and therefore those people don't deserve ‘an easy way out’

Binus · Today 11:15

icecreamflowers · Today 11:07

If a new drug came on the market for people with cancer or Alzheimers' nobody who didn't have cancer or Alzheimers' would be wanting to use it.

Depends entirely on the perceived benefits.

JacquesHarlow · Today 11:26

I find it fascinating how aggressive the defensive arguments are from those who take weight loss medicine.

You've decided all the answers already, and no one can tell you otherwise right?

minipie · Today 11:26

susiedaisy1912 · Today 11:14

Exactly, you’ve hit the nail on the head. Deep down people are pissed off that overweight people have a tool to help them loose weight without suffering from constant hunger and unhappiness. It’s a deep rooted bias that most of us have without even knowing why that links obesity to greediness and slovenliness and therefore those people don't deserve ‘an easy way out’

Edited

Really?

Obesity costs millions every year in NHS costs for obesity related conditions and in disability benefits. Why would anyone want others to stay obese?

I do think there is some envy among people who are slightly overweight (but wouldn’t qualify for the jabs) that people who are very overweight can get this helpful drug when they can’t. Especially as people who started out very overweight can then keep taking it even when they reach a healthy weight.

But that’s not at all the same as thinking obese people shouldn’t have help to lose weight. At the end of the day WLI still require eating less, it’s not a magic pill that lets you eat cake all day and still lose.

Binus · Today 11:36

It's hard to separate what others want for obese people from the pervasive and incorrect belief that diet and exercise are viable alternatives. You'd have to correct for that.

But I do get that a person whose genuine belief, contra to evidence, is that obesity can generally be reversed through traditional methods may be giving what they truly think is good advice.

Multiple posters have done that on this thread. If I had to bet, I don't think they all understood they're actually suggesting something that is more likely than not to mean people continuing to be exposed to the risks of obesity.

SwingTheMonkey · Today 11:37

JacquesHarlow · Today 11:26

I find it fascinating how aggressive the defensive arguments are from those who take weight loss medicine.

You've decided all the answers already, and no one can tell you otherwise right?

I find it laughable that a random internet user thinks they have the medical insight to tell anyone whether or not they should be using a specific medication.

SwingTheMonkey · Today 11:40

Frequency · Today 11:14

If an Alzheimer's drug came out that was heavily marketed as being the only way you could avoid alzheimers, was being sold for profit with little to no medical oversight, and being used by people who do not need it, I can guarantee people would have something to say about the potential fallout and side effects.

You cannot compare WLI to other prescription medications because no other prescription medications are marketed and sold this way.

WLI are most certainly not marketed as the only way someone can lose weight. For a vast number of obese people, this will be the case though.
As for the abuse of this medication- absolutely not a reason for it not to be available. As a number of posters have pointed out, a huge number of drugs are routinely used by those who don’t need them. Why is nobody bleating about that?

Pikachu150 · Today 11:43

Frequency · Today 11:14

If an Alzheimer's drug came out that was heavily marketed as being the only way you could avoid alzheimers, was being sold for profit with little to no medical oversight, and being used by people who do not need it, I can guarantee people would have something to say about the potential fallout and side effects.

You cannot compare WLI to other prescription medications because no other prescription medications are marketed and sold this way.

They are not being marketed or sold in different way. Drug companies have to follow the usual rules. There are no adverts for them in the UK, let alone marketing campaigns stating they are the only way to lose weight.

Pikachu150 · Today 11:44

JacquesHarlow · Today 11:26

I find it fascinating how aggressive the defensive arguments are from those who take weight loss medicine.

You've decided all the answers already, and no one can tell you otherwise right?

Who is being aggressive apart from you?

Witchonenowbob · Today 11:48

JacquesHarlow · Today 11:26

I find it fascinating how aggressive the defensive arguments are from those who take weight loss medicine.

You've decided all the answers already, and no one can tell you otherwise right?

I find it interesting that some random in the internet thinks can tell people who have researched and actually used the drug that they’re wrong.

Pikachu150 · Today 11:50

pdjafcwtaoa65 · Today 09:53

What’s interesting is that a lot of the risks that come with WLI are lower for people with lower BMI, if you have less to lose you’re less likely to go onto higher doses, and less likely to experience rapid weightloss which is the driving cause behind most of the more severe repercussions of WLI. I suspect that’s why prescribers such as Voy have started prescribing at a BMI of 25 off label.

What are they prescribing off label?! Very risky and they could get in a lot of trouble.

SwingTheMonkey · Today 11:51

Witchonenowbob · Today 11:48

I find it interesting that some random in the internet thinks can tell people who have researched and actually used the drug that they’re wrong.

This is it! They think they’re telling us something we don’t already know! We know the risks of gallbladder disease/ pancreatitis etc (that were already risks when we were overweight btw). We know that there’s a possibility that something might crop up in years to come.
But using the knowledge we have now, which is that they are safe to use and very effective, we have taken the calculated risk to use the drug.
Its so tiresome being treated like we’re stupid and haven’t weighed up the potential risks for ourselves.