To wonder if there will be any fall out from skinny jabs?

[TheLemonGuide]

Everyone I know is now suddenly very slim. Okay, im exaggerating slightly, but genuinely, most of my friends who were previously overweight are all now slim thanks to skinny jabs. I am delighted for them! It seems unbelievable to think that a jab can cure this obesity crisis, but I am so pleased my friends and a couple of family members are able to live a healthier life thanks to this.

My only slight concern is, is this something that is going to be too good to be true? Do you think there will be any long term repercussions, or are we right to just celebrate this medication as a cure for something that so many have been battling for so long?

The root cause, in many cases, is poverty. Ironically.

I'm on a WLI currently, and this is also something I've been a bit concerned about. It makes me think of when the COVID jabs were sped through to the world, and there then turned out to be some reactions (blood clotting or something) to the AstraZeneca ones, which then had to stop being offered to certain people, and is now no longer used in the UK. Then there was the drug - thalidomide? that thousands of pregnant women were given (years ago) for morning sickness that caused birth defects and was later taken out of circulation due to how dangerous it was to unborn babies.
I'm sure something on that scale is unlikely, but modern medicine isn't always fail safe.
That being said, the worry is not a huge one, and some of them have been around for quite a long time - wegovy I think has been around much longer and already used in the NHS to treat diabetes, is more tested etc.
Not sure about MJ, but I think with any newer medications there's always going to be a risk of unknown longer term side effects. I guess it's weighing it up for most people, risks versus benefits.

If something sounds too good to be true, it probably isn't true. There is a price to pay for every choice.

I know at least four people on them and suspect a couple more.

Two were overweight, one was slim, the other somewhere in between.

Some have made a real effort to get good nutrition in. Others have eaten shit, just in smaller portions. All get it privately, at least one lied to get it. It's wildly easy to get now, but I'm sure they will crack down on this.

If I were obese I'd take them, absolutely. So many benefits and the drawbacks vs obesity are worth it. But I don't agree with thin people taking them. That seems risky.

GLP-1s have been around for over 20 years, and the ones in use today almost ten. There are risks with any drugs. But these seem here to stay (and I’d love Mounjaro to be approved for type 1 diabetics).

If you understand that it doesn't stop hunger entirely, you can't then make an argument based on a premise that it does.

People become obese because they eat too many calories. Insulin resistance via processed food is one way that it happens, but you'll be looking a while for evidence that it's the way 99.9% of obese people reached a 30 BMI. The fact is that humans evolved for a world where we had to survive periods of very low food/starvation, and thus we were incentivised to eat lots of high calorie food when we could get it. Medicine isn't taking us back to that.

I was only marginally overweight. Took it for 2 months, lost a stone and came off it. Cant imagine that will have lifelong negative effects.

That’s what’s stopped me from taking them. I’m slightly overweight, in that I’m a size 14 and would like to be a 12. But I just don’t think they’ve been used for long enough to show us that they’re safe long term. I just feel it’s going to be one of those situations where in a couple of decades there’s going to be adverse health situations on the back of taking them. But I appreciate I might be just one voice, and people will disagree with me.

It doesn’t have to stop it entirely for it to be detrimental long term. A strong appetite is a fundamental thing.

The evidence is right there in history. We only have to go back pre WW2 to see that obesity was incredibly rare. Genes don’t change in a century but the way the world eats now is vastly different. And we see high obesity levels emerging now in countries like China as they adopt Western ways of eating.

The calorie thing is a smoke screen. The way one consumes too many calories is by eating the wrong foods. Very easy to eat 5000 calories of cake. Why? because it spikes insulin and blood sugar leaving one craving more. It’s messing up the hormones.

Try eating 5000 calories of steak or salmon!

I’d like to, but just can’t take the risk of losing my already thin hair.

Food was expensive pre world Ww2.

My concern is the muscle loss. Up to 40% of weight lost on these jabs can be muscle and bone, not fat. People are getting lighter but frailer. That's a disaster waiting to happen, especially for older users

ALL the people taking WLI seem to either be on MN or know someone on MN. Google says 1.6 million people in the UK take it.
It seems strange that you know so many of them.

I think the answer is that we don't know the long term impact. We can't know yet.

Were you concerned about the obesity related health risks these women also faced or is it just now you are concerned about their health?

Research was done before introducing them and is still ongoing. Am vaguely linked to something that’s hopefully getting ethical approval soon to dig deeper into the wider benefits from the emotional side not just weight loss (eg use of anti depressants, just feeling generally better, being more energetic so can spend time with kids, do activities, move more etc)

It’s possible to retrain your entire mind and body to just move more and not eat any processed shit. Drink water. Even when life gets stressed. Find ways to fit a walk in. If you’re in full time work and too busy to do
that…you get a 30 min break it’s the law so go and walk around outside or in your building if it’s bad weather. Our bodies aren’t built for eating crap and not moving. It’s as simple as that

Of course. It is possible to be concerned about more than one thing though.

I do think that we should be concerned about bone health. I think the risks will become more pronounced in a few years. Of course cardiac issue related to obesity is still concerning, and those issues might not go away when people lose weight.

I think they have been massively rushed onto the market because they've been touted so effectively in a political sphere as the solution to the expensive obesity crisis.
I also think that any expression of concern over the safety or long-term efficacy of these injections is usually met by accusations of jealousy similar.

Unless those people are women, in which case it will be down to ‘hormones’ or ‘depression’ or ‘anxiety’. I guess it’s better than ‘hysteria’…

I also think that being ultra-skinny is going to rapidly go out of fashion now that the general population have access

in what aspect have they been “rushed onto the market” @plsdontlookatmecan you explain what you mean by that?

There are other things that people do to change their bodies that are horribly risky but we don't seem to get continual posts about them..... cheap dental implants and various forms of plastic surgery are the first that come to mind.

The question is are they leading a ‘healthier life’ as you say or just a thinner life?

Forgive me for asking a prurient question, that I would be too embarrassed to ask IRL, but does it hurt? I’m terrified of needles because injections and blood draws are always so painful, and often wonder how awful it must be for eg diabetics having to inject themselves every day!

Surely, most of female nervous issues could be solved by a good seeing-to?

YANBU, I wouldn’t touch them with a barge pole.

As usual, fast forward twenty years and they'll carry a health warning or be found to cause cancer.