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AIBU?

Share your dilemmas and get honest opinions from other Mumsnetters.

To wonder if there will be any fall out from skinny jabs?

558 replies

TheLemonGuide · 20/04/2026 16:40

Everyone I know is now suddenly very slim. Okay, im exaggerating slightly, but genuinely, most of my friends who were previously overweight are all now slim thanks to skinny jabs. I am delighted for them! It seems unbelievable to think that a jab can cure this obesity crisis, but I am so pleased my friends and a couple of family members are able to live a healthier life thanks to this.

My only slight concern is, is this something that is going to be too good to be true? Do you think there will be any long term repercussions, or are we right to just celebrate this medication as a cure for something that so many have been battling for so long?

OP posts:
InfoSecInTheCity · 20/04/2026 22:28

AllTheChaos · 20/04/2026 22:21

Forgive me for asking a prurient question, that I would be too embarrassed to ask IRL, but does it hurt? I’m terrified of needles because injections and blood draws are always so painful, and often wonder how awful it must be for eg diabetics having to inject themselves every day!

It doesn’t hurt at all. The needle is tiny, the injection is all pre-prepared in a pen, so you just screw a needle tip on, wind the knob on the end of the pen till it won’t wind any more, lightly press the needle it into belly or thigh and push the button. You barely even feel it go in.

Lifeisaneducation · 20/04/2026 22:30

If I was to have any concerns over WLI, it would be that WLI focus almost wholly on a number on the scale, and health is so much more than that!

We live in a society that celebrates being slim and is fat phobic, whilst tempting people to overindulge everywhere they go, by the sheer volume of fast food/coffee shops/bakeries/sweet shops/takeaways.
We can get processed food delivered to our doors every single day, and the supermarkets have multiple aisles of processed snacks and ready meals.
We have been taught from as far back as we can remember that we need to eat at least 3 times a day, and we are bombarded with food at every angle, from cooking programmes on tv to all of these places we can buy food that is rubbish but oh so convenient.
High calorie/processed food gives a dopamine rush, and when people are living lives that are more stressful than ever before, and food is so convenient to buy, it is an easy way to get a dopamine fix.
People are encouraged to incorporate food into almost every celebration, and we now eat for pleasure and to treat ourselves rather than for sustenance, and yet we simultaneously criticise people for being obese.

It seems it is okay to enjoy food and eat what you desire, so long as you aren't fat!
As soon as you are fat, you are supposed to exercise an incredible amount of self control and ignore all of the temptation regarding food that is out there, and stop using food as a reward or a pleasure, yet the people who have been using food as a way of making themselves feel temporarily better, are given no effective alternatives, so they just end up feeling deprived.
Many people I know who are obese use food as a coping mechanism, it makes them feel good, they look forward to 'treating' themselves, they can't afford the money or the time for good therapy and food is a quick fix.
Imo, eating crap gives many people a temporary lift and that's how they cope.
My mother is a prime (possibly extreme) example. She is morbidly obese, has chronically low self esteem, has been in abusive relationships, has almost no friends, is desperately lonely and has turned to food to fill the emotional void inside for decades.
My mother doesn't eat because she is actually hungry, she eats because it makes her feel good, she sees it as a treat, and she feels so shit so much of the time that it is a relief to feel good some of the time.
My child, who fortunately is not overweight, has ADHD, and eats crap to get a dopamine fix, because ADHD feels like shit.
In both of those examples, WLI would only reduce the hunger AFAIK, but it wont give my mother her self esteem, because her self esteem was destroyed years before she was obese, and it wont give my mother or my child the dopamine or comfort they use food to get.
It will simply reduce their appetite.
And while the weight loss may give them a temporary boost mentally, the old issues are still there!
So instead of focusing on the number on the scales, we need to look deeper at why people are using food to feel better in the first place, to the point where it is affecting their health.
Obviously this doesnt apply to every overweight person, but it does apply to many.
A lot of overweight people are not over eating because they are hungry, my mother doesn't know what it feels like to be hungry. They are using food as a crutch, a temporary relief from issues they are dealing with, and while WLI mean you lose interest in food, the original issues are still there, you just don't want to use food to deal with them.
That doesnt mean you are 'cured' of your issues, so how do WLI help long term?

babyproblems · 20/04/2026 22:32

I think one of the fall outs will be people still poisoning themselves with toxic chemicals in food / UPF. It doesn’t really solve the problem of healthy eating, healthy attitude to food and understanding nutrition / cooking. It may help to reach an end goal and some of the understanding but it allows space for another consumer product to exist, alongside the ones which cause obesity in the first place.

Ukefluke · 20/04/2026 22:34

HoppityBun · 20/04/2026 21:01

Great. But people who are not obese are not being prescribed GLP. There’s a strong link between being overweight and developing psoriatic diseases but there’s also a high discontinuation rate.

There is absolutely no research on using GLP-1 medications for people with psoriatic diseases who are not overweight and not diabetic.

I am not overweight and not diabetic and has psoriatic arthritis when I was not over weight.
In addition all my skin allergies and contact sensitivities have gone. The drugs have stong anti inflammitory properties and there are on going studies into this.

WaterandSandy · 20/04/2026 22:34

Lifeisaneducation · 20/04/2026 22:30

If I was to have any concerns over WLI, it would be that WLI focus almost wholly on a number on the scale, and health is so much more than that!

We live in a society that celebrates being slim and is fat phobic, whilst tempting people to overindulge everywhere they go, by the sheer volume of fast food/coffee shops/bakeries/sweet shops/takeaways.
We can get processed food delivered to our doors every single day, and the supermarkets have multiple aisles of processed snacks and ready meals.
We have been taught from as far back as we can remember that we need to eat at least 3 times a day, and we are bombarded with food at every angle, from cooking programmes on tv to all of these places we can buy food that is rubbish but oh so convenient.
High calorie/processed food gives a dopamine rush, and when people are living lives that are more stressful than ever before, and food is so convenient to buy, it is an easy way to get a dopamine fix.
People are encouraged to incorporate food into almost every celebration, and we now eat for pleasure and to treat ourselves rather than for sustenance, and yet we simultaneously criticise people for being obese.

It seems it is okay to enjoy food and eat what you desire, so long as you aren't fat!
As soon as you are fat, you are supposed to exercise an incredible amount of self control and ignore all of the temptation regarding food that is out there, and stop using food as a reward or a pleasure, yet the people who have been using food as a way of making themselves feel temporarily better, are given no effective alternatives, so they just end up feeling deprived.
Many people I know who are obese use food as a coping mechanism, it makes them feel good, they look forward to 'treating' themselves, they can't afford the money or the time for good therapy and food is a quick fix.
Imo, eating crap gives many people a temporary lift and that's how they cope.
My mother is a prime (possibly extreme) example. She is morbidly obese, has chronically low self esteem, has been in abusive relationships, has almost no friends, is desperately lonely and has turned to food to fill the emotional void inside for decades.
My mother doesn't eat because she is actually hungry, she eats because it makes her feel good, she sees it as a treat, and she feels so shit so much of the time that it is a relief to feel good some of the time.
My child, who fortunately is not overweight, has ADHD, and eats crap to get a dopamine fix, because ADHD feels like shit.
In both of those examples, WLI would only reduce the hunger AFAIK, but it wont give my mother her self esteem, because her self esteem was destroyed years before she was obese, and it wont give my mother or my child the dopamine or comfort they use food to get.
It will simply reduce their appetite.
And while the weight loss may give them a temporary boost mentally, the old issues are still there!
So instead of focusing on the number on the scales, we need to look deeper at why people are using food to feel better in the first place, to the point where it is affecting their health.
Obviously this doesnt apply to every overweight person, but it does apply to many.
A lot of overweight people are not over eating because they are hungry, my mother doesn't know what it feels like to be hungry. They are using food as a crutch, a temporary relief from issues they are dealing with, and while WLI mean you lose interest in food, the original issues are still there, you just don't want to use food to deal with them.
That doesnt mean you are 'cured' of your issues, so how do WLI help long term?

Well said.

Caplin · 20/04/2026 22:36

I think we are only just discovering how many other health issues are positively impacted by GLP-1s, like heart disease, and anecdotally addiction, ADHD etc. science will need to catch up, but meanwhile doctors across the world are experimenting and seeing positive results for lots of things not weight related.

My Dad was obese and died from heart failure (well it was Covid that did for him). He had ulcerated legs, water retention and was well over 30 stone. He was too heavy to operate on. If he fell we needed special hoists to get him off the floor. Anyway, I decided that I didn’t want that after battling obesity for about a decade. It was an awful way to live in those final years.

I know someone with diabetes who had bad side effects and ended up in hospital. She asked if she should stop and the doctor said it would still be better if she stayed on and lost weight! To be honest GPs don’t really understand GLP-1s yet and they were upping her dose too fast rather than moving up when her dose stopped working. But she no longer needs insulin.

SilenceInside · 20/04/2026 22:39

@Lifeisaneducation well if your mum is morbidly obese she will be healthier and likely to live longer whilst she figures out how to improve her self esteem, if she lost weight with WLI. Her self esteem will also be improved by no longer being morbidly obese, as we all know that people are not treated kindly by society for being obese, particularly morbidly so. Possibly the relief of feeling in control and feeling healthier might also give her the headspace to address her issues. And if not, at least she would have lost the weight and not have increasing health issues to add to her problems.

shihtzuu · 20/04/2026 23:10

Loose skin and surgery to remove it

Flumposie3 · 20/04/2026 23:23

I had surgery in November. No privacy on the Ward when surgeons did their rounds so you heard everything. One young lady was in with gallbladder issues. Told the surgeon she was on weight loss jabs, he told her that she had diagnosed herself. That they were averaging 2 people a week with gallbladder issues and the nhs as a whole was seeing this due to weight loss jabs. The poor girl was upset as she said she was trying to improve herself . Buying them online. What I heard him telling her put me off trying them.

WaterandSandy · 20/04/2026 23:32

Flumposie3 · 20/04/2026 23:23

I had surgery in November. No privacy on the Ward when surgeons did their rounds so you heard everything. One young lady was in with gallbladder issues. Told the surgeon she was on weight loss jabs, he told her that she had diagnosed herself. That they were averaging 2 people a week with gallbladder issues and the nhs as a whole was seeing this due to weight loss jabs. The poor girl was upset as she said she was trying to improve herself . Buying them online. What I heard him telling her put me off trying them.

Is it the jabs or the rapid weightloss that they facilitate which cause gallbladder issues though?

Pikachu150 · 20/04/2026 23:41

vitahelp · 20/04/2026 22:20

The question is are they leading a ‘healthier life’ as you say or just a thinner life?

They reduce the risk of diabetes and heart disease in obese people so they do lead to a healthier life.

icecreamflowers · Yesterday 00:21

Allseeingallknowing · 20/04/2026 21:46

I’d like to, but just can’t take the risk of losing my already thin hair.

A friend I only see twice a year as we live in different cities has gone on them. She has a thirty-year history of eating disorder, and was not what anyone would call overweight prior. She is clearly very proud of her extreme weightloss now, and did look cute in her tiny-sized outfit. However, she has gone from having a massive thick mane of curly hair to a few sparse strands.

WaterandSandy · Yesterday 00:22

icecreamflowers · Yesterday 00:21

A friend I only see twice a year as we live in different cities has gone on them. She has a thirty-year history of eating disorder, and was not what anyone would call overweight prior. She is clearly very proud of her extreme weightloss now, and did look cute in her tiny-sized outfit. However, she has gone from having a massive thick mane of curly hair to a few sparse strands.

She obviously didn’t disclose her history of ED then?

icecreamflowers · Yesterday 00:24

WaterandSandy · Yesterday 00:22

She obviously didn’t disclose her history of ED then?

Clearly.

MeridaBrave · Yesterday 06:09

Flumposie3 · 20/04/2026 23:23

I had surgery in November. No privacy on the Ward when surgeons did their rounds so you heard everything. One young lady was in with gallbladder issues. Told the surgeon she was on weight loss jabs, he told her that she had diagnosed herself. That they were averaging 2 people a week with gallbladder issues and the nhs as a whole was seeing this due to weight loss jabs. The poor girl was upset as she said she was trying to improve herself . Buying them online. What I heard him telling her put me off trying them.

I think the gallbladder issues come from rapid weight loss which is clearly easier on the jabs. I’ve seen it on WLI threads people are frustrated with a reasonable and steady and healthy 0.5kg loss a week and want more faster so increase the dose. The issue is the lack of regulations, unlike in the USA when it’s mainly doctor and insurance - here it’s online pharmacies where the patient not a doctor decides on the dose changes. And people chop and change to get the best deals.

10namechangeslater · Yesterday 06:32

AuntChippy · 20/04/2026 19:12

Exactly this. People are defensive because they can see straight through the faux ‘concern’.

It isn’t faux concern at all. I have very real concerns about them and with a BMI of 31 I could use them but I won’t. It’s real genuine concern.

susiedaisy1912 · Yesterday 06:52

Rapid weight loss will increase the risk of developing gallstones no matter what method you use. It’s just that for the first time in medical history we have a medication that can cause rapid weight loss so therefore the cases of gallstones have increased. It’s not rocket science.

NeverDropYourMooncup · Yesterday 07:08

AllTheChaos · 20/04/2026 22:21

Forgive me for asking a prurient question, that I would be too embarrassed to ask IRL, but does it hurt? I’m terrified of needles because injections and blood draws are always so painful, and often wonder how awful it must be for eg diabetics having to inject themselves every day!

My injections are biologics, which are a significantly larger volume than WLIs. Ive had several types, two of which were pen injectors and two syringe types - the pen types could sting a bit, but the syringe ones are no real difference to if the cat flexes his claws a little deeper than I'd prefer.

My friend says her WLIs are so thin that she barely feels them at all. Another one who has them for diabetes control struggles with injections due to sight loss so he gets his wife to do it for him - he reckons that 90% of his difficulty is that he doesn't have control, so he's tense and expecting something 'bad' to happen.

One of the things to bear in mind is that there are lots of nerve endings around the inside of an elbow and vaccinations go into muscles taking up space, which isnt the case with WLIs. And you're in control.

I think you would be surprised how much easier it is.

Fizzy89 · Yesterday 07:24

I think my concern with them is the amount of people who seem not to truly understand how it works/how to look after themselves on it.

I have a friend who does tend to be a bit 'bull in a China shop' about things but in general is an intelligent girl and she started them and I asked was she taking the protein and vitamin supplements she needs (cos id read up on it) and she thought that was fine... cue bad side effects.

Some people seem to think it 'stops fat', people are cracking open the jab pens to get extra bits of dose left behind.
Its all badly managed and I agree in a country with the NHS it concerns me if we are going to have to pay to mop up a mass of side effects related to it

LightandAiry · Yesterday 07:25

Sadly someone close to me has severe health issues due to extreme obesity. WLI prescribed by the GP hopefully will be a way out, but I assume they'll need to take them for life. This is a life ruined by obesity causing immobility.... overeating is an addiction and any other risks relating to the meds are worth taking.

I wouldn't take them myself with my BMI of 30, I am trying to reduce glucose levels with diet and exercise....I am put off by the expense mainly and the thought of putting the weight back on when stopping the jabs.

The drugs haven't been around long enough to know the long term effects but they're a good thing for many people.

AgnesMcDoo · Yesterday 07:42

Better physical and mental health
Less diabetes, high blood pressure, heart disease, heart attacks, some cancers.

Yes there is fallout and it’s great and long term this means reduced costs to the NHS and more people paying income tax for longer cause they are fit enough to work and still alive.

susiedaisy1912 · Yesterday 07:56

Fizzy89 · Yesterday 07:24

I think my concern with them is the amount of people who seem not to truly understand how it works/how to look after themselves on it.

I have a friend who does tend to be a bit 'bull in a China shop' about things but in general is an intelligent girl and she started them and I asked was she taking the protein and vitamin supplements she needs (cos id read up on it) and she thought that was fine... cue bad side effects.

Some people seem to think it 'stops fat', people are cracking open the jab pens to get extra bits of dose left behind.
Its all badly managed and I agree in a country with the NHS it concerns me if we are going to have to pay to mop up a mass of side effects related to it

I agree it’s been badly managed by the government and the NHS. They knew these drugs were coming for several years before they hit the market. They knew the extent of the obesity crisis in the uk and yet they still chose to do very little to ensure those who needed it most could get it. Instead spending billions on other things.

Binus · Yesterday 08:06

darksideofthetoon · 20/04/2026 21:45

It doesn’t have to stop it entirely for it to be detrimental long term. A strong appetite is a fundamental thing.

The evidence is right there in history. We only have to go back pre WW2 to see that obesity was incredibly rare. Genes don’t change in a century but the way the world eats now is vastly different. And we see high obesity levels emerging now in countries like China as they adopt Western ways of eating.

The calorie thing is a smoke screen. The way one consumes too many calories is by eating the wrong foods. Very easy to eat 5000 calories of cake. Why? because it spikes insulin and blood sugar leaving one craving more. It’s messing up the hormones.

Try eating 5000 calories of steak or salmon!

5000 calories is an odd choice. Most people need much less than that daily, so we will not be using it as our example. There are people on here whose maintenance calories are in the low 1000s. It is, of course, extremely doable to eat more than that amount in meat and fish.

Obesity was likely incredibly rare pre WW2 because there were no populations rich enough to feed everyone a calorie surplus for their whole lives until very shortly before. And so many people smoked.

I certainly agree that we eat very differently now to the 1920s, plus fortunately the famine rates and the number of adults who grew up without enough food are both lower today. But none of these things explain why it's bad to alter someone's hunger cues if they're telling them to eat more than they'll burn off.

pdjafcwtaoa65 · Yesterday 08:09

Lifeisaneducation · 20/04/2026 22:30

If I was to have any concerns over WLI, it would be that WLI focus almost wholly on a number on the scale, and health is so much more than that!

We live in a society that celebrates being slim and is fat phobic, whilst tempting people to overindulge everywhere they go, by the sheer volume of fast food/coffee shops/bakeries/sweet shops/takeaways.
We can get processed food delivered to our doors every single day, and the supermarkets have multiple aisles of processed snacks and ready meals.
We have been taught from as far back as we can remember that we need to eat at least 3 times a day, and we are bombarded with food at every angle, from cooking programmes on tv to all of these places we can buy food that is rubbish but oh so convenient.
High calorie/processed food gives a dopamine rush, and when people are living lives that are more stressful than ever before, and food is so convenient to buy, it is an easy way to get a dopamine fix.
People are encouraged to incorporate food into almost every celebration, and we now eat for pleasure and to treat ourselves rather than for sustenance, and yet we simultaneously criticise people for being obese.

It seems it is okay to enjoy food and eat what you desire, so long as you aren't fat!
As soon as you are fat, you are supposed to exercise an incredible amount of self control and ignore all of the temptation regarding food that is out there, and stop using food as a reward or a pleasure, yet the people who have been using food as a way of making themselves feel temporarily better, are given no effective alternatives, so they just end up feeling deprived.
Many people I know who are obese use food as a coping mechanism, it makes them feel good, they look forward to 'treating' themselves, they can't afford the money or the time for good therapy and food is a quick fix.
Imo, eating crap gives many people a temporary lift and that's how they cope.
My mother is a prime (possibly extreme) example. She is morbidly obese, has chronically low self esteem, has been in abusive relationships, has almost no friends, is desperately lonely and has turned to food to fill the emotional void inside for decades.
My mother doesn't eat because she is actually hungry, she eats because it makes her feel good, she sees it as a treat, and she feels so shit so much of the time that it is a relief to feel good some of the time.
My child, who fortunately is not overweight, has ADHD, and eats crap to get a dopamine fix, because ADHD feels like shit.
In both of those examples, WLI would only reduce the hunger AFAIK, but it wont give my mother her self esteem, because her self esteem was destroyed years before she was obese, and it wont give my mother or my child the dopamine or comfort they use food to get.
It will simply reduce their appetite.
And while the weight loss may give them a temporary boost mentally, the old issues are still there!
So instead of focusing on the number on the scales, we need to look deeper at why people are using food to feel better in the first place, to the point where it is affecting their health.
Obviously this doesnt apply to every overweight person, but it does apply to many.
A lot of overweight people are not over eating because they are hungry, my mother doesn't know what it feels like to be hungry. They are using food as a crutch, a temporary relief from issues they are dealing with, and while WLI mean you lose interest in food, the original issues are still there, you just don't want to use food to deal with them.
That doesnt mean you are 'cured' of your issues, so how do WLI help long term?

I completely agree with all of this and the sentiment behind it, but what I will say is that injections really switch off that food noise/reward need centre for a lot of people. This enables them to pause and make better choices, to not be a slave to those feelings or constant marketing and availability of food.

One of the biggest impacts seems to be to stop that dopamine seeking behaviour. This pause can enable people to reflect on their relationship with food and most importantly as you say, health. They can be an incredible tool, but it is all in how they are used.

It’s very personal, and it’s why people get defensive when generic statements are made.

Pikachu150 · Yesterday 08:15

10namechangeslater · Yesterday 06:32

It isn’t faux concern at all. I have very real concerns about them and with a BMI of 31 I could use them but I won’t. It’s real genuine concern.

You should be more concerned about diabetes and cardiovascular disease.