To think that if people can take Mounjaro forever for maintenance (which I support FAOD)

[Fragmentedbrain]

Why can't everyone just buy it when they feel the need?

Basically this means that people who lost weight in a different way are denied this long term amazing support tool while those who started off on it can keep using it. But if you purposefully regained a bit of weight to become "eligible" for the injections you could take them and then have Mounjaro available for life.

This seems very unfair to me.

Congrats. Some of us want to live easier lives that are pain free.

I've taken saxenda and I totally agree with you OP. The line to prescribe has to be drawn somewhere, but realistically there is no physical or metabolic difference between me when I started WLI with a bmi of 30, and someone with a bmi of 28-29. The only difference would be a few glasses of water or being constipated for a day.

I think in future (after the patent expires) the drugs may become a regular thing for almost anybody who feels they need it to take, similar to the contraceptive pill or PrEP for HIV prevention.

refusing hrt unless you have a medical reason not to take it is very foolish

Not everyone needs HRT. My DM never took it and never had any problems and no issue with bone density and lived to the age of 85. I expected to as I had low oestrogen symptoms from age 46/47 when I was on the progesterone only pill, and switched back to the combined pill for a short while. I've now stopped all hormonal birth control at nearly 50, my periods appear to have stopped and I feel great with no low oestrogen symptoms, so I won't be leaping onto HRT if I don't need it.

You won't know you needed it until your Dexa scan about a decade too late

“The only difference would be glass of water or being constipated” I’m not sure I agree there - in the last day or so I’ve lost 2lbs and my bmi has only gone down by 0.3

@Fragmentedbrain I’m 57, menopause at age 48, and I don’t take HRT. I did try it for a month, out of curiosity, and I felt better but gained half a stone, so gave up. But I’m a GP and from a generation that was taught how closely linked HRT and breast cancer were. The “million women study” was quite clear, that risk was significantly raised beyond 4-5 years of treatment.

I’m not entirely sure what happened, because I blinked and suddenly the “million women study” is disregarded, and HRT is given out like smarties. I assume the study was found to be inaccurate, or maybe exaggerated, I’m not sure.

Of course I prescribe HRT to my patients within the current NICE guidelines, but for myself I can’t help remembering those risks. I don’t think that makes me foolish.

And you won't know it gave you breast cancer until a decade too late.

Yes, that's what blanket, uninformed medical advice from internet strangers sounds like.

I went from 14 stone to 11 on Mounjaro and started having stomach trouble so came off. I checked my bmi and realised that I was still technically overweight so tried to go back on after a three month break. In that time I realised my mistake as the food noise came back and a few pounds went back on with no sign of stopping.

I was denied access to the meds because my bmi was too low even though it was still considered overweight. I hate to admit it, but I lied to get back on it.

I started again at 2.5mg and am now on 10mg and have only managed to lose another 9lbs. However, the aim is not to be super skinny, the real benefit for me is the huge reduction in food noise. If it has not been an issue in your life then dieting might be a simple calories in/calories out equation but for me and many people who use GLp-1, the reduction in food noise is a game changer. I finally feel free of food.

I wish there was more support for people who have this type of experience because it seems that most people think it's a matter of willpower when clearly it isn't.

There is a lot less risk in Mounjaro than many other things we do every day.

For example?

Driving a car? About 13% of all external deaths in the UK are car accidents. People drive or ride in cars every day.

How about the risk of being obese and failing to make any effort at all, to stop stuffing your mouth until expensive injections were available.

why?

they said that about statins. I don’t think they’re blanket prescribed any more because they turned out to not be the no side effects, all benefit panacea they were first marketed as.

i currently don’t feel the need for HRT. Why would I get it when I have no clinical issues, I’m fit, I’m healthy, I’m late into menopause (50’s and still regular), I lift weights and do impact exercise to maintain bone density.

from my pov there’s no benefit to it currently. I’ve had a look (albeit quick) and I can’t see that it should be prescribed to every single woman or the risks are unacceptably high if you don’t take it.

😂You can't argue with one breathe that the jabs have too many side effects and are dangerous then, with the next, argue that being obese has too many effects and is dangerous. You can't control yourself from being rude so I'm not sure why you're preaching self-control to others.

I think all the women dying from a trip in their front garden illustrate your folly. Thank God I wasn't middle aged under your generation's"care".

I think my osteoporotic mum would murder the smug GP who denied her hrt if only the physical interaction wasn't so dangerous to her.

"Your Dexa scan" - like it's something people have by default on the NHS. I'm almost 50 now and have been reading about menopause for at least ten years, at least from when I had my first hot flush aged 39 and had what turned out to be endometriosis and bilateral endometrial cysts and rejected the proposal to have a hysterectomy or oophorectomy or drugs to put me into early menopause unless except as a last resort - which was not needed in the end. I first went to a gym and lifted weights aged 18 so it has been over 30 years of weight bearing exercise. I will have a private Dexa scan in a few years and may well take HRT if I need to. At the moment my body is having a break from 25+ years of hormonal contraception and seeing if my periods have stopped properly for 12 months which seems to be key in deciding which type of HRT to have, if any. But if I continue not to have no symptoms and feel good, I'm not going to leap into taking something that may make me feel shit and put weight on, and certainly not only 8 months into knowing whether my periods have definitely stopped.

I agree with you OP. I am a healthy weight but the ‘food noise’ that people talk about mounjaro dulling is very loud for me. I would love to experience life without it.

I agree with you OP. I am a healthy weight but the ‘food noise’ that people talk about mounjaro dulling is very loud for me. I would love to experience life without it.

I can understand that and don't think it is a bad idea. There would probably need to be evidence of the previous obesity though and it is now very expensive so many may decide it isn't worth it.

So I’ve had a think about this and have a feeling this is the logic:

obese person. The risk of obesity vs. Wld is greater, so they are prescribed.

dose, any side effects, and whether the patient tolerates it is established, they remain on it and lose weight.

now this is where the difference between an obese person who is no longer obese through conventional diet and wld matters…

both patients are now only “overweight” so the risk of the wld is higher compared to weight. The person already on wld is tolerating, few side effects, working well, so they continue. The person the same bmi who hasn’t had wld before has to establish whether they tolerate it, whether the side effects are minimal etc. the risks of wld outweigh the need to lose weight at that bmi.

does that make sense?

It's not just the weight loss
It's the food noise.

I had binge eating disorder, all gone now and the relief is immense.
I wasn't even particularly obese but get mj prescribed on the nhs due to diabetes.

I've lost 1.5 stone but will take it for life now.

Do you really think that's the case? Read any of the support threads on this and you'll find hundreds of stories about women who've tried every other method going, over decades. Metabolism is an incredibly complex thing that we are constantly learning about and witless twats who post on SM such pearls of wisdom as "eat less move more" and "get off the sofa" and "lazy" are many years behind in their understanding.

I have lost a lot of weight on it which is fabulous. However the main reason that I want to stay on it that it now that I am slim ( body weight more than halved) is that it has virtually eliminated the symptoms of my auto immune disease.

From hideously swollen disfigured joints, limited mobility with chronic pain...... I now have normal looking joints, off all pain killers and able to move and exercise without pain. Last week I climbed a mountain at high speed. Next day I was fresh as a daisy with no swelling or pain, despite a very ardous day. I couldn't have done that pre MJ.

This miracle, because that's what it feels like, is not related entirely to weight loss. The effect actually happened within a month of the first injection when I had only lost a couple of pounds.

For comparison I was for over a decade on immunosupressants so toxic that I needed my blood screened every month to check that it wasnt damaging my organs. Pain meant that I was on 4 naproxen per day, another nasty drug.
These drugs did not help my condition..

MJ helped me virually over night. I don't take the nasty meds any more and havent had pain med since I started the jabs I am pain free and mobile.

It isn't licenced for this, but research shows that GLps do have a strong positive effect on inflammation. The documented MJ risks are not a patch on the risks of the horrible drugs I was on.

I will move heaven and hell to stay on it.