I second the gardening service, a few times a year to help you get and keep on top of the garden, if you can afford it. Say every 3 months get them in, cut grass, cut back trees, weed and plant new flowers and then you just do the maintenance in between. The mice I hate hate hate hate!! Sorry meeces, it is you or me and I can buy traps lol. I'd be sealing every damn hole up with expanding foam to halt their march, buying my weight in traps and reclaiming my space.Plus a few sonar plug in's as they do help somewhat.
The spiders I hear they hate chestnuts and some essential oils, I just kill em here. although they don't bother me as such. Hoover is great for sucking em up and disposing of afterwards.
If you can afford a cleaning service occasionally as a treat to yourself and hubby ( more you) lets face it, as women always do the majority of the housework then by all means spend the money on these things. Get them in to do a deep clean once a month/every 2 months and you just pick up the slack in the meantime. Life is tough enough, there is no need to make it tougher as long as you can afford to do these things.
The house I'd personally set one day aside and get stuck into it, change beds, hoover bedrooms, clean bathrooms and kitchen and living room and then go to one of those garage washer/driers and do the whole batch of laundry in one go.
The other alternative is to pay a local once a week to come in for a half day and give you a hand with the cleaning.
I have gotten to the stage in my life there are things I love to do, and things I will gladly pay to have done for me. No regrets either as I'd rather sit and read or relax in my spare time