I don't think anyone can guarantee anyone else will feel the same...I couldn't wait to get away from the area I grew up in, and at 18 was able to move away. I moved to another part of the city, had a whole life there of my own away from my parents...then inexplicably sold up & moved a mile away from where my parents live. I never thought I'd see the day.
The whole time I was there, I was kicking myself for moving, yet loved the house I was in and had spent a lot of money on it, so didn't wish to move. Added to which, all my work was local. In hindsight, I should never have bought a house that was located where it was, but I fell in love with it at first sight.
After about seven years, fate eventually intervened, by sending me some appalling neighbours, which meant I had no qualms about moving. I was torn between moving to a much better part of the same district, or moving back to the area across the city, where I felt I'd carved a life for myself when I was a late teen.
I went for the latter, but the problem was I couldn't afford a house there (I'd had a flat before, and even they had rocketed in price), so went a few miles further out, and from the day I got the keys I hated everything about it, not least because all that I now knew and needed was the other side of the city. Within weeks we decided to move - 12 months later we'd sold and moved to the better part of the area I grew up in. Only due to the costs involved we settled on a maisonette, which has not gone up in price like the houses have.
It's been well over 20 years since I first moved back to this area - I still can't believe I ever did, and I am by no means in love with it (plus I still have all the horrible memories of growing up here) but it's where I feel safe, and above all, I know the area well. The older I get, the more I fear having to move to a place I don't know.
Regrets? Plenty. My only advice to you OP would be to make sure you have your reason "why?" and that you crunch the numbers properly.