@SolitaryMind no I'm referring to men who take female hormones, have all male parts removed, female outer parts created deliberately & facial surgery & laser hair removal done to become more feminine.
A man with a penis removed as per your example is only female if the intention to become and live fully as a woman is there and if he does the rest / or most of the above plus changes his name & changes the sex on his birth certificate.
For example some men with eg Prostate Cancer sometimes need hormone therapy - which can make male breasts more obvious, smoothe the skin, make hair luxuriant etc an effect a bit like HRT, as my grandad found.
But taken in isolation that is just a cancer treatment. It does not at all make a man a female.