I think this is quite rare though, and is mainly just an awkward person's fantasy - that the social, good looking people will end up ugly with crap jobs at age 22. Nah, doesn't work like that. Things like social skills, fashion sense, looks, body size and shape, intelligence and charisma are lifelong characteristics.
I do believe that long-term popularity - or lack thereof - in the developing phase has lifelong consequences.
What I have noticed is that many of the popular girls in my school have failed their dream lives (all sorts, including living abroad, being a model, film star, just generally living that life of glamour). They all have ordinary lives now, the cool smokers have definitely aged more with their habit. Three were pregnant by the time we left sixth form.
The cool boys fared worse, partially because being cool also meant messing around, not getting the grades and generally just not being able to show respect to authority. It hasn't served them well in real life and while some have managed to grow up, some of the most popular boys from my school time can barely hold down a job.
I went to a grammar school, so we were all intelligent, but the top 5% who actively engaged were still bullied relentlessly. And we did also have an outsider group, who were all a bit awkward and shy, often not thin, usually without fashion sense and just not mainstream.
The vast majority of this group have gone on to shine after high school. Most of the fat girls are now thin and sport a youthful look. Most of the plain girls have developed varied, but interesting styles. The top students academically have all gone on to life success (I know, I am one of them). One awkward girl is making her name abroad as a punk singer.
The point is, when you spend your youth being popular, it changes how you see life. We have seen it on here in the pretty women threads that keep popping up - there are genuinely people whose life is easier when they conform to beauty standards. It means that they never have had to work or try too hard to achieve success, and that does, eventually, lead to poorer outcomes.
I believe that the people who struggled in high school kept working hard - they've always had to, to overcome not fitting in. That work ethic sticks, and so does the work towards trying to fit in, hence why so many of us found their style and actively keep fit.
This isn't about US cliches. It's proven by research (just look at how differently golden children and black sheep of narcissist parents develop) and applies in high school social circles, too.