I get severe skin rashes if I use biological washing powder, so I use non-bio.
But I've got white clothes and sheets with stains on them I can't get out (mascara mostly), and dresses that will still smell of cigarettes or wine or whatever if I've been to a party (and not from me smoking - from talking outside to people who are, or from a glass of wine or lager or whatever being spilt on the table). I end up needing to put things through the washing machine multiple times.
I tried biological on some whites with stains last year and the clothes were gleaming, and then they gave me a rash that took months to shift. Anyone else in the same boat that's found a washing powder that's non-bio but actually cleans clothes? I'm currently using Fairy, having been told by my doctor it was best for 'curing' the self inflicted rash.