Things to think about:
Pension? (or are you expecting other taxpayers to fund this?)
Long-term illness?
Boredom? You say you're burnt out now, but maybe you're just in the wrong job.
Your skills? How adaptable or transferable are they?
Stability of your relationship.
Children? Their security, and/or that of older family members?
Experience of living outside commuterland?
My father never really had to work for a living (trust fund, investments etc). He did, however, in two very useful professions which were also things he enjoyed doing. He still stopped working for money at around the age of 50, but became really directionless, and took up fads and phases to fill in his time and keep his interest alive and his learning to continue.
Having watched this, and also seen my full-time SAHM mother lose her direction, & watch her zest for life diminished when we children all went to university, I have come to think that we all need work of some kind: work that rewards us (not just monetarily) and challenges us.
19th century Russian novels are full of aristocrats wanting something useful to do in the world. I don't really need to work for my living (said trust fund) but I do, because I like the independence , and I'm also been very privileged to have excellent health & education, and I want to make a return to my society, in some sort of way.
Maybe you just need a short sabbatical? Can you arrange with your job to take a few months out? Obviously at the moment the standard "go travelling" isn't possible, but before you sell up & drop out, you really should give it a try out, for a short time.
I think we all need a purpose in life - maybe you just haven't found yours yet?