Sounds like OP lives locally to both family and friends, which just isn't the case for many people.
If people are going to have to be away from home overnight, or even for two nights, in order to attend the wedding at all, then it can be just too difficult and expensive to arrange childcare, and just easier not to go.
I doubt many people are "offended" by it. It's just the situation means they can't go. Bride and groom shouldn't be offended either.
We had a family wedding recently, DH cousin. Nephews and nieces invited, not our DC though as cousins children. Hundreds of miles away for us, grandparents at wedding too, so would have been big detour to drop DC at my parents instead, kids would have had to miss school too. So we couldn't go. Disappointed but that's life. If it had been local to us we probably could have managed, but lots of people don't live near family now.
People should recognise that when planning their wedding, though obviously still their choice to have children or not.