There's a lot of conflation going on here. People talking about drug abuse and tolerance as if they're pharmacologists or have ever taken anything stronger than some whisky
Alcohol dependence - alcoholism - works differently to psychoactive substances. And taking LSD or mushrooms isn't the same as that or something so completely addictive as heroin or strong opioids.
I haven't taken LSD - don't fancy it, wouldn't know where to get it, am not interested - but the POINT of microdosing is doing it in such small amounts and irregularly that any psychological dependence or tolerance doesn't build up. Plus these drugs work differently to something like weed or coke to which tolerance is something more linear
These women aren't harming anyone and in most cases, trying to treat mental illness. Having taken antidepressants, strong painkillers etc, the physical effects of withdrawing from the antidepressants was always the worst thing
And they're not gateway drugs. Something like mushrooms are very different from heroin