For your house size and radiator number I would get a 30KW combi (if you have to have a combi). It's more than sufficient. Don't go for smaller as the hot water throughput won't be enough .
Best makes to go for based on my experience and taking to many heating engineers:
- Vaillant
- Worcester Bosch
After that you can go for glow worm who I think are owned by vaillant and then Baxi, or even Majn which is made by Baxi but is more basic.
The price also depends on the warranty.
I would get one with at least 7 or 10 years warranty. You can get cheaper ones with 2 year warranties.
To keep your warranty valid, the boiler has to be serviced every year, within the right time frame or not too early and not too late. I think it's a 60 day window but check.
We have experience with both types of set-up and I have to say I much prefer a system boiler with unvented cylinder to the combi we have in our other property. I find combis a PITA. The water is always cold when you turn on the tap and often doesn't heat up by the time you have finished washing your hands or washing a few things. Taking a bath is also horrible. If you need to top the water up after 15 mins the hot tap just gives cold water for ages ruining the bath.
We have a system boiler and small unvented cylinder providing hot water and heating for a large 2 bed property and I'm so glad I went for a like for like recently instead of switching to a combi. We have a combi in another place and I don't like it although it makes sense as its not used much.
One more thing I learned. Unvented cylinders like Megaflow are REALLY well insulated. They basically lose something like just 2 degree of heat in 24 hours. So we don't worry about heating excess hot water in our tank, it stays boiling hot overnight and we just use it the next day. I love this set up even though it takes a bit more space.