Los Angeles is obviously Birmingham (UK). Sheesh.
(multi ethnic, sprawl, spaghetti motorways, nation's 2nd city grudges)
Florida => Great Yarmouth/Hemsby/Walton on Naze/Clacton (rt wing, tatty, sprawl, flat, old people)
San Francisco => Brighton (woo, thinks they are very clever, stupid house prices)
Boston => Newcastle on Tyne (edgy, cold, clever)
Detroit -> Leicester?
Chicago -> Glasgow (multi ethnic, take no crap, bit scary)
Agree Montana/Idaho/Wyoming -> Lake District or Kansas -> LINCS.
Portland OR is weird, Oregonians are very very strange. Can't think of anywhere in UK as quirky. Somewhere in Yorkshire, maybe?
Seattle may match to Cambridge for high tech sectors, prosperity, political island in the region